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Laser micro control device and method for transportation and orientation of movable corpuscle and cell

A technology of directional movement and particles, applied in the field of lasers, can solve problems such as biological cell damage

Inactive Publication Date: 2008-06-25
ZHEJIANG UNIV
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Problems solved by technology

[0005] The purpose of the present invention is to solve the defect that the traditional method of using electrodes to transport and orientately move cells is easy to cause damage to biological cells, make full use of the characteristics of the laser beam, and provide a laser for transporting and orientably moving particles and cells Microcontrol device and method

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  • Laser micro control device and method for transportation and orientation of movable corpuscle and cell

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Embodiment Construction

[0028] As shown in Figure 2, the laser micro-control device for transporting and directional moving particles and cells includes a laser 2, a beam conversion system 3, a focusing system 4, a two-dimensional moving object platform 6, and a microscopic observation system 7. A microscopic observation system 7 is provided under the moving object loading platform 6. The light source system is a laser 2, a beam conversion system 3, and a focusing system 4 placed in sequence. The laser 2, the beam conversion system 3, and the focusing system 4 are placed on the same optical axis. The light source system and the two-dimensional moving object loading platform 6 are placed in the same plane.

[0029] The light source system is a laser 2, a beam conversion system 3, and a focusing system 4 placed in sequence, and the laser 2, the beam conversion system 3, and the focusing system 4 are placed on the same optical axis. There are multiple light source systems. The laser beam mode emitted b...

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Abstract

The present invention relates to a laser micro-control device and method for the transportation and directional movement of particles and cells. In the device, a light source system and a two-dimensional moving loading platform are arranged in the same plane. The light source system is a laser, a light beam converting system and a focusing system which are orderly placed. The laser, the light beam converting system and the focusing system are arranged on the same optical axis. The present invention utilizes the characteristic that laser beam has gradient force and radiation force to restrict particles and cells needing transportation and directional movement in a light beam focusing area, and can carry out the transportation of particles and cells through a single laser beam as well as the directional movement of particles and cells through two intersecting laser beams, so as to realize the method of controlling particles and cells. The present invention can utilize laser micro-control technology to realize the direct transportation and directional movement of particles and cells, and can be applied to micro-fluidic chemistry or biological analysis systems.

Description

technical field [0001] The invention relates to the field of laser technology, in particular to a laser micro-control device and method for transporting and directional moving particles and cells. Background technique [0002] Since Ashkin used the gradient force and radiation force of the laser to trap and control glass particles in 1970, more and more people have paid attention to it, especially in 1986, he invented the laser optical tweezers technology. Since then, the laser optical tweezers technology has been developed rapidly. It has become an effective means of trapping and manipulating particles and cells. A wide range of particles can be manipulated at the same time, including neutral atoms and molecules, as well as micro-medium spheres and living cells, etc. [0003] As we all know, light has energy and momentum, so when photons interact with particles, the momentum and energy of the photons will exchange with the particles, resulting in the sharpening and scatter...

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Application Information

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IPC IPC(8): G02B27/00G21K1/00G01N15/00G01N37/00
Inventor 陆璇辉赵承良陈和
Owner ZHEJIANG UNIV
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