A kind of injection preparation containing argatroban

[0020] Example 1: Argatroban water injection

[0021] prescription:

[0022] components Dosage Argatroban 100g Absolute ethanol 400g D-sorbitol 300g Water for Injection q.s.1000ml Co-made 1000ml

[0023] Preparation:

[0024] Take 400g of absolute ethanol, add D-sorbitol and stir to dissolve, add argatroban, stir and dissolve, add 0.1% activated carbon for needles according to the prepared amount, heat the liquid to about 60°C, stir for 20min, filter and decarbonize, Add water for injection to the total amount, and detect intermediates. After passing the test of the intermediate, fine filter with a 0.22 μm microporous membrane, fill in vials, 2.5 ml per vial, stopper, and cap. Moist heat sterilization, you can.

[0025] Example 2: Argatroban water injection

[0026] prescription:

[0027] components Dosage Argatroban 50g Absolute ethanol 400g D-sorbitol 300g Water for Injection q.s.1000ml Co-made 1000ml

[0028] Preparation:

[0029] Take 400g of absolute ethanol, add D-sorbitol and stir to dissolve, add argatroban, stir and dissolve, add 0.1% activated carbon for needles according to the prepared amount, heat the liquid to about 60°C, stir for 20min, filter and decarbonize, Add water for injection to the total amount, and detect intermediates. After passing the test of the intermediate, fine filter with a 0.22 μm microporous membrane, fill in vials, 2.5 ml per vial, stopper, and cap. Moist heat sterilization, you can.

[0030] Example 3: Argatroban water injection

[0031] prescription:

[0032] components Dosage Argatroban 200g Absolute ethanol 400g D-sorbitol 300g Water for Injection q.s.1000ml Co-made 1000ml

[0033] Preparation:

[0034] Take 400g of absolute ethanol, add D-sorbitol and stir to dissolve, add argatroban, stir and dissolve, add 0.1% activated carbon for needles according to the prepared amount, heat the liquid to about 60°C, stir for 20min, filter and decarbonize, Add water for injection to the total amount, and detect intermediates. After passing the test of the intermediate, fine filter with a 0.22 μm microporous membrane, fill in vials, 2.5 ml per vial, stopper, and cap. Moist heat sterilization, you can.