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Electrode, electrochemical sensor and device and method of operation thereof

An electrochemical and sensor technology, applied in the field of collecting biomedical data and/or information, can solve the problem of complex pill design

Active Publication Date: 2011-12-14
SCOTTECH MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0008] Providing sensors that include a reagent space with a removable cover complicates the design of swallowable pills

Method used

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  • Electrode, electrochemical sensor and device and method of operation thereof
  • Electrode, electrochemical sensor and device and method of operation thereof
  • Electrode, electrochemical sensor and device and method of operation thereof

Examples

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preparation example Construction

[0181] Preparation of working electrode

[0182] The invention also provides a preparation method of the working electrode.

[0183] Accordingly, in one aspect there is provided a method of making a working electrode comprising the step of mixing a matrix comprising carbon or graphite with a first reagent, a second reagent, or both. The matrix comprising carbon or graphite is preferably a carbon or graphite paste, or a carbon or graphite ink.

[0184] Preferably, the first reagent, the second reagent, or both reagents are independently milled prior to mixing with the carbon or graphite-containing matrix.

[0185] Preferably, the first reagent, the second reagent, or both are independently ground and mixed by vortex prior to mixing with the carbon or graphite-containing matrix. The resulting mixture can be homogenized in a mortar and then stirred. This process can be repeated until the desired uniformity of the paste is obtained.

[0186] In some embodiments of the inventio...

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Abstract

A method for amperometric detection of proteins, especially haemoglobin in faeces, using an electrochemical sensor. The electrochemical sensor includes: a working electrode having an electrically conductive matrix holding a first reagent and / or a second reagent, the second reagent being an oxidising agent, or a precursor thereof, for the first reagent; a counter electrode and optionally a reference electrode; wherein a reaction between the first reagent and the oxidising agent is catalysed by the protein to provide a detectable signal at the working electrode. The electrically conductive matrix is an electrically conductive carbon- or graphite-containing matrix or an electrically conductive porous matrix.

Description

[0001] related application [0002] This application claims priority from GB 08208175.5, filed 13 November 2008, the entire contents of which are incorporated herein by reference. technical field [0003] The present invention generally relates to processes, uses and methods utilizing electrodes, sensing devices and sensing devices, and sensing systems. The present invention is particularly, but not exclusively, related to collecting biomedical data and / or information. Background technique [0004] Some gastrointestinal (GI) disorders are difficult to detect, and current detection systems that incorporate camera sensors into swallowable pills are often not accurate enough to detect problems at an early stage. Gastrointestinal bleeding is a common symptom of diseases such as Crohn's disease, ulcerative colitis, ulcers and cancer. Bleeding in the gastrointestinal tract goes unnoticed unless it reaches a point where other symptoms (such as anemia) appear or if there is blood ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/72G01N33/487G01N27/30
CPCG01N27/3271G01N33/725G01N27/4161G01N27/308G01N33/726
Inventor 文森特·伯努瓦
Owner SCOTTECH MEDICAL CO LTD
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