Application of gingerol and cerous oxalate composition to preparation of toxicity-decreasing and efficacy-increasing drugs for cancer chemotherapy
A composition and technology of gingerol, which is applied in the direction of drug combination, digestive system, anti-tumor drugs, etc., can solve the problems of patients with severe vomiting, strong toxic and side effects, and high price, and achieve good anti-emetic and tumor-inhibiting effects
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[0019] The first step: preparation of gingerol
[0020] Cut the ginger into thin slices, dry it naturally, grind it into powder with a high-speed universal pulverizer, pass through a 30-mesh sieve, put the sifted fine powder into a 5000mL large grinding bottle, soak it with 6 times the amount of acetone at room temperature for 72 hours; ℃, ultrasonic extraction at 40KHz ultrasonic frequency for 15min; centrifugation to obtain the supernatant, and the residue was discarded; the supernatant was filtered under reduced pressure, and the filtrate was placed in a rotary evaporator for vacuum concentration to obtain a ginger extraction mixture, and then the mixture was Gingerol was obtained by repeated concentration, drying and purification.
[0021] Step 2: preparation of preparation
[0022] (1) Preparation of pharmaceutical composition capsule preparation of the present invention
[0023] Weigh 80 mg of gingerol and 20 mg of cerium oxalate prepared in the above steps, and simult...
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