A kind of pharmaceutical composition and preparation method and application

The invention relates a medicinal composition as well as a preparation method and applications of the medicinal composition. The medicinal composition is prepared from the following medicinal materials: herba agrimoniae, radix salviae miltiorrhizae, peach kernels, lignum dalbergiae odoriferae, radix ophiopogonis, rhizoma coptidis, radix scrophulariae, cortex moutan and leeches. Herba agrimoniae and radix salviae miltiorrhizae are taken as monarch drugs, peach kernels, lignum dalbergiae odoriferae and cortex moutan are taken as ministerial drugs, radix ophiopogonis, radix scrophulariae and leeches are taken as assistant drugs, the monarch drugs, the ministerial drugs and the assistant drugs perform the corresponding roles and are also matched with each other, and thus the medicinal composition has the efficacies of clearing Ying heat and eliminating toxins, promoting blood circulation to remove meridian obstruction, and strengthening the body resistance, especially has the functions of improving the cardiac function and the myocardial pathological form, promoting the angiogenesis, inhibiting the myocardium cell apoptosis, inhibiting the inflammatory reaction, protecting the endothelial cells, and the like, and has very good curative effects in treating or preventing coronary heart disease.