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A three-dimensional stretching culture system for nerve axons

A technology of pulling and axons, applied in the field of medical nerve cultivation, to achieve the effects of good biocompatibility, convenient experimental control, and not easy to deform

Active Publication Date: 2022-05-03
HUBEI UNIV OF TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This device is used for stretching and culturing nerve axons, but the device adopts the wall-attaching method to cultivate nerve cells, resulting in cells generally in a two-dimensional state, but the nerve bundles in the organism are three-dimensional cylinders, and only three-dimensional nerve bundles , can be more directly applied to patients

Method used

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  • A three-dimensional stretching culture system for nerve axons
  • A three-dimensional stretching culture system for nerve axons
  • A three-dimensional stretching culture system for nerve axons

Examples

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Embodiment Construction

[0033] refer to Figure 1-Figure 6 , the nerve axon three-dimensional stretching and cultivating system of the present invention comprises a pulling and cultivating device and a control system connected with the stretching and cultivating device, the stretching and cultivating device comprises a horizontally arranged cultivating platform 1, and a A fixed base 10 and a movable base 16 on the cultivation platform 1, the movable base 16 is provided with a cell culture tank 2, and the cell culture tank 2 is connected with a pulling mechanism and a rotating mechanism;

[0034] The control system of the present invention includes a controller 15 connected with the pulling mechanism and the rotating mechanism, and an upper computer 14, and the upper computer 14 is connected with the controller 15; wherein, the upper computer 14 can control the pulling parameters through programming, including The controller 15 is used to receive the control instructions from the host computer 14 for ...

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Abstract

The invention belongs to the technical field of medical nerve cultivation, and in particular relates to a three-dimensional stretching and cultivation system for nerve axons, which includes a stretching and cultivation device and a control system connected with the stretching and cultivation device. The stretching and cultivation device includes a horizontally arranged A cultivation platform, a fixed base and a movable base arranged on the cultivation platform, a cell culture tank is arranged on the movable base, and the cell culture tank is connected with a pulling mechanism and a rotating mechanism; the control system includes a control system connected with the pulling mechanism and the rotating mechanism. device, and host computer, the host computer is connected with the controller; the invention can flexibly control the length, direction and speed of axon growth; it can be compared with the axon cells cultured in a two-dimensional environment, so as to cultivate axon cells for patients Higher quality nerve tissue with appropriate length and regular growth can be used for repairing nerve loss and has broad application prospects.

Description

technical field [0001] The invention relates to the technical field of medical nerve cultivation, in particular to a three-dimensional pulling cultivation system for nerve axons. Background technique [0002] According to the results of the second national sample survey of disabled people, there are 82.96 million disabled people in my country, accounting for 5% of the total population, of which 24.12 million are physically disabled, accounting for 29.07% of the total number of disabled people, and about 6 million amputee patients are physically disabled. and millions of paraplegics due to spinal cord injuries. In addition, due to accidents, natural disasters, malignant diseases and other reasons, a large number of patients with neurological injuries will be added every year. [0003] After nerve injury, the two ends of the disconnected nerve need to be pruned, and filled with nerve tissue or other biological materials as bridging materials to induce the two ends of the nerve...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M3/00C12M1/36
CPCC12M23/20C12M23/38C12M23/48C12M23/58C12M35/04C12M41/00
Inventor 唐茜唐榕李肖蒯波
Owner HUBEI UNIV OF TECH
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