Propylgallate injection and its preparing process

[0145] Example 1-4: Preparation of Propylgallate Injection Small Volume Injection

[0146] The small-volume injection of propyl gallate injection contains propyl gallate, glycerin, EDTA-2Na and water for injection, and the ratio of each component is shown in Table 8. Table 8

[0147] Example 1 2 3 4

[0148] Propyl gallate (kg) 18 1 0.6 0.024

[0149] Glycerin (L) 30 10 6 3 EDTA-2Na (kg) 0.02 0.02 0.02 0.02

[0150] Add water for injection to 100L 100L 100L 100L

[0151] The preparation method is as follows:

[0152] Add 80L of water for injection into the batching tank, start the stirring paddle to stir, add glycerin and EDTA-2Na to make it completely dissolve at 75°C, then add propyl gallate, keep stirring to make it completely dissolve; add 0.1kg of activated carbon for needles, Insulate and stir at ℃ for 20 minutes, turn off the mixer, start the infusion pump, decarbonize and filter the medicinal solution through titanium rods, and put it into the dilute dispensing ta...

[0154] Example 5-12: Preparation of Propylgallate Injection Large Volume Injection

[0155] This propyl gallate injection large-volume injection contains propyl gallate, sodium chloride or glucose, and water for injection, and the ratio of each component is shown in Table 9. Table 9

[0156] Example 5 6 7 8 9 10 11 12

[0157]Propyl gallate (g) 24 24 36 36 72 72 180 180

[0158] Sodium chloride (g) 850 0 900 0 900 0 950 0

[0159] Glucose (g) 0 4500 0 5000 0 5000 0 5500

[0160] Add water for injection to 100L, and it can be made into different specifications such as 500, 250, 100, 50ml / bottle.

[0161] The preparation method is as follows:

[0162] Add 80L of water for injection into the batching tank, start the agitator to stir, add sodium chloride or glucose to dissolve completely at 70°C, then add propyl gallate, keep stirring to dissolve completely; add 100g of activated carbon for needles, Keep warm and stir for 25 minutes, turn off the mixer, start the infus...