Pulse-promoting slow-release capsule and preparing method

[0037] Prescription: Ginseng 100g, Ophiopogon japonicus 200g, Schisandra chinensis 100g, microcrystalline cellulose 100g, hollow capsule 65% ethanol solution

[0038] Preparation method:

[0039] The process route is as follows

[0040]

[0041] The ginseng, Ophiopogon japonicus and Schisandra chinensis are washed, crushed, soaked in 65% ethanol solution for 24 hours, and then subjected to wet treatment, and the obtained extract is spray-dried at 5-7ml / min to obtain a drug dry powder. The microcrystalline cellulose and the dry drug powder were put into a coating pan with a rotational speed of 15r / min, and 500g of dry pellets were obtained at 40°C and 10r / min. Pack into capsules to get 1000 capsules.

[0042] After testing, it contains ginsenoside Rg 1 , Re total content accounts for 0.25%, ophiopogon saponin B, D total content accounts for 0.25%, schisandra alcohol A content accounts for 0.30%.

[0044] Prescription: Ginseng 100g, Ophiopogon japonicus 200g, Schisandra chinensis 100g, hypromellose 120g, hollow capsule, 65% ethanol solution

[0045] Preparation method:

[0046] The process route is as follows

[0047]

[0048] Wash the ginseng, Ophiopogon japonicus and Schisandra chinensis, crush them, soak them in 65% ethanol solution for 24 hours, and then carry out wet treatment to obtain the extract. Put the hypromellose into the coating pan, spray the extract at a rate of 5-7ml / min at 40°C, and obtain 500g of skeleton pellets after drying. Pack into capsules to get 1000 capsules.

[0049] After testing, it contains ginsenoside Rg 1 , Re total content accounts for 0.25%, ophiopogon saponin B, D total content accounts for 0.35%, schisandra alcohol A content accounts for 0.30%.

[0051] Adopt embodiment 1 or 2 to prepare the technique of matrix pellet, different slow-release materials such as methyl cellulose (MC), hypromellose (HPMC), povidone (PVP), ethyl cellulose, cellulose acetate 1. Polymethacrylate 80-100g, prepare 500g of skeleton-type pellets, and then pack into capsules to obtain 1000 capsules. Its detection result is basically identical with embodiment 1,2.