The invention discloses a method for performing 
genome amplification by using 
embryo blastula-stage cells, performing 
chromosome detection on the preimplantational 
embryo by combining a high-flux sequencing technique and screening out the 
chromosome normal 
embryo. The method can comprehensively and completely analyze the 
genetic variation information of the embryo 
genome, thereby instructing the preimplantational embryo selection, reducing the 
hereditary diseases and enhancing the success rate of 
test tube babies. The method comprises the following steps: 
blastula-stage trophocyte separation; 
genome amplification; 
DNA (deoxyribonucleic acid) segmentation; and 
Proton library establishment, mounting sequencing and 
sequencing data analysis. By using the 
blastula-stage embryo to perform trophocyte separation detection, the method avoids the injuries of cleavage-stage 
cell separation to the embryo, obtains higher 
cell quantity than the cleavage stage, and enhances the success rate and amplification effect of 
genome amplification. After the blastula-stage embryos are subjected to the natural 
elimination process, the high-quality blastula-stage embryo is selected for detection, thereby saving the cost.