125results about How to "Increase permeation" patented technology

A filtration system and a method of cleaning a particle and / or colloidal fouled filtration membrane are provided. The filtration system includes at least one filtration membrane disposed in a casing, and at least one ultrasonic transducer in direct contact with a fluid to be filtered. Ultrasonic energy is emitted by the ultrasonic transducer in the direction of the filtration membrane. Dislodged particles cleaned by the ultrasonic energy from the filtration membrane are carried away in a cross-flow stream and wasted or recycled back to the beginning of the treatment process. The ultrasonic transducer can be fixed or movable. The filtration system can use different filtration membrane configurations such as, but not limited to, tubular, flat sheet, hollow fiber and spiral wound membranes.

A recording method is provided which enables formation of an image with high image density and low graininess. The recording is conducted by using a recording method using a first aqueous ink for higher-density recording and a second aqueous ink for lower-density recording, characterized in that the first aqueous ink comprises at least water, a water-insoluble coloring material, and plurality of water-soluble organic solvents, the plurality of water-soluble organic solvents including a good medium or good mediums for the water-insoluble coloring material and a poor medium or poor mediums for the water-insoluble coloring material, the ratio B / A in the second aqueous ink being less than the ratio B / A the first aqueous ink, where A denotes the total content (mass %) of good medium based on the total mass of the aqueous ink and B denotes the total content (mass %) of poor medium based on the total mass of the aqueous ink; and the second aqueous ink has the same hue as the first aqueous ink.

A formulation, method and system for the topical, transdermal or transmucosal administration of a therapeutically effective active agent. Particularly, the invention provides a formulation, system and method for enhancing the permeation or penetration of active agents across the dermal or mucosal surfaces of a mammalian subject. The formulation includes a plant extract of the genus Curcuma of the family Zingiberaceae, a germacrone, or a natural or synthetic constituent thereof, which has been found to increase penetration of the active agent across the dermal or mucosal surface. If desired, a secondary permeation enhancer of a polyalcohol, a monoalkyl ether of diethylene glycol, a tetraglycol, or a mixture thereof can be used for certain active agents for optimal permeation enhancement.

A method of vehicle modulated administration of an anticonvulsive agent to the nasal mucous membranes of humans and animals is disclosed. The vehicle system is an aqueous pharmaceutical carrier comprising an aliphatic alcohol, a glycol and a biological surfactant such as a bile salt or a lecithin. The pharmaceutical composition provides a means to control and promote the rate and extent of transmucosal permeation and absorption of the medicaments via a single and multiple administration. Nasal administration of the pharmaceutical preparation produces a high plasma concentration of the anticonvulsant nearly as fast as intravenous administration. Such compositions are particularly suitable for a prompt and timely medication of patients in the acute and / or emergency treatment of status epilepticus and other fever-induced seizures.

The present disclosure relates to an electronic therapy device including automatic controlled application of energies along with feedback control using sensors for improved synergistic effects and further the device is configured to be used for longer periods of time for improved and optimal therapeutic results without causing any adverse effects, the device can be used for pain management, healing, fitness, cosmetic and topical delivery related applications and a method for performing electronic therapy using the said portable electronic device.

The present invention relates to releasable fusogenic lipids and nanoparticle compositions containing the same for the delivery of oligonucleotides and methods of modulating gene expression using the same. In particular, this invention relates to releasable fusogenic lipids containing an imine linker and a zwitterionic moiety.

The present disclosure relates to an electronic therapy device including automatic controlled application of energies along with feedback control using sensors for improved synergistic effects and further the device is configured to be used for longer periods of time for improved and optimal therapeutic results without causing any adverse effects, the device can be used for pain management, healing, fitness, cosmetic and topical delivery related applications and a method for performing electronic therapy using the said portable electronic device.

The present invention generally relates to composite laminates and uses thereof in articles in need of protection from mechanical damage and water or oxygen based degradation.

A transdermal or topical composition including anticholinergic agents, such as oxybutynin, a urea-containing compound and a carrier system. A method is disclosed for treating a subject for urinary incontinence while reducing the incidences of peak concentrations of drug and undesirable side effects.

A vehicle for topical application which contains a liquid eutectic mixture of hydrophobic compounds to improve solubility of pharmaceutically active component and enhance topical and transdermal delivery.

A porous membrane of vinylidene fluoride resin excellent in hydrophilicity and having a good balance among strength, elongation and water permeation rate, which is thus useful as a microfiltration membrane or a separator of battery. The porous membrane is formed from a copolymer of 100 mols of a vinylidene fluoride monomer and 0.01-10.0 mols of a hydrophilic monomer having at least one species of hydrophilic group selected from epoxy group, hydroxy group, carboxy group, ester group, amide group and acid anhydride group.

A multilayer structure with improved permeation for atmospheric diffusion of aromatic products wherein the structure comprises: a permeable membrane wherein said permeable membrane comprises at least two polymeric layers wherein the polymer of each layer is independently selected from the group consisting of polyethylene, very low density polyethylene, low density polyethylene, ethylene methylacrylate copolymer; a release layer wherein said release layer comprises a nylon polymer or a ethylene vinyl alcohol copolymer wherein the release layer is adhered to most inner polymeric layer of the permeable member which comprises the permeable membrane and wherein the adhesion between release layer and the adjacent layer of the polymeric permeable membrane is a relatively weak bond compared to the bond between the layers of the polymeric permeable membrane; and an impermeable membrane wherein said impermeable membrane comprises one or more layers wherein the materials which comprise the individual layers of the impermeable membrane are independently selected from metal or foil and wherein said impermeable portion is laminated to said release layer.

A transdermal or topical composition including anticholinergic agents, such as oxybutynin, a urea-containing compound and a carrier system. A method is disclosed for treating a subject for urinary incontinence while reducing the incidences of peak concentrations of drug and undesirable side effects.

A novel method of vehicle modulated administration of an anticonvulsive agent to the mucous membranes of humans and animals is disclosed. The vehicle system is an aqueous pharmaceutical carrier comprising an aliphatic alcohol (10–80%) or a glycol (10–80%), and their combinations with a biological surfactant such as a bile salt or a lecithin. The pharmaceutical composition provides a means to control and promote the rate and extent of transmucosal permeation and absorption of the medicaments via a single and multiple administration. Nasal administration of the pharmaceutical preparation produces a high plasma concentration of the anticonvulsant nearly as fast as intravenous administration. Such compositions are particularly suitable for a prompt and timely medication of patients in the acute and / or emergency treatment of status epilepticus and other fever-induced seizures.

The present invention is based on the surprising antiseptic nature of chlorhexidine when combined with essential oils. It has been found that chlorhexidine, combined with an essential oil, is surprisingly effective at penetrating the skin surface and providing an antiseptic effect within the skin. It has also been found that a combination of chlorhexidine and eucalyptus oil is surprisingly effective as an antimicrobial against Staphylococcus epidermidis.

This invention relates to a new cellulose triacetate hollow fiber alloy film, in addition to a preparing method. It mixes the cellulose triacetate and acid, alkali resistance high molecular material to modify, which can decrease the sensitivity of the cellulose triacetate to acid and alkali, and increase the bioavailability and permeable quantity of the film. The film is manufactured with 45-85% cellulose triacetate, 5-25% disperse component, 10-30% pore former. The invention can be widely used in water softening and sea water desalting.

Aerogel compositions that include polyamic amides, methods for preparing the aerogel compositions, and articles of manufacture that include or manufactured from the aerogel compositions are described.

An external preparation containing the following components (A), (B), (C), and (D):(A) a non-steroidal analgesic / anti-inflammatory agent,(B) a terpene and / or an essential oil containing a terpene,(C) a higher alcohol, and(D) a polyoxyalkylene alkyl ether and / or a polyoxyalkylene alkenyl ether. The external preparation of the present invention has improved skin permeation, and can thus be effective at a low concentration, and also has excellent appearance.

The invention relates to the field of cosmetics and provides a co-conveying nano composition of phenylethyl resorcinol. The co-conveying nano composition comprises phenylethyl resorcinol, other skin whitening active components, a nano medicine carrier as well as solvent complex lipid and water, wherein the phenylethyl resorcinol accounts for 0.1-10% of the total mass of the co-conveying nano composition; the other skin whitening active components comprise at least one of an antioxidant, a cutin peeling type active substance, a melanosome transferring inhibition active substance, an anti-glycation active substance and an anti-allergic agent; the nano medicine carrier comprises raw materials of an emulsifier, a Anti-allergic agent and polyhydric alcohols. Due to compounding of different skinwhitening components and carrying of the nano medicine carrier, a remarkable synergetic effect can be achieved, irritation of high-concentration phenylethyl resorcinol can be remarkably reduced, andthe co-conveying nano composition is good in stability, excellent in skin whitening effect, good in water solubility, good in skin permeability and widely applicable to cosmetics.

Disclosed is a ceramic filter formed on a porous substrate and having good permeability and good selectivity. The ceramic filter comprises a monolith-type alumina porous substrate (2) having an average pore size of 1 to 30 [mu]m, a first surface dense layer (3) having an average pore size of 0.1 to 3 [mu]m and provided on the substrate (2), a second surface dense layer (4) having an average pore size of 0.01 to 0.5 [mu]m and provided on the first surface dense layer (3), a third surface dense layer (5) formed with a titania sol, having an average pore size of 0.3 to 20 nm and provided on the second surface dense layer (4), and a carbon membrane layer (6) which is a molecular sieve carbon membrane and provided on the third surface dense layer (5).

The invention relates to the field of cosmetics, in particular to a multi-effect hydroxyl pinacolone retinoate nano composition which comprises hydroxyl pinacolone retinoate, nicotinamide, glycyrrhizic acid, an emulsifying agent, a co-emulsifying agent and polyhydric alcohol. The hydroxyl pinacolone retinoate accounts for 0.1-10% of of the total mass of the nano composition; the nicotinamide accounts for 0.1-10% of the total mass of the nano composition; and the glycyrrhizic acid accounts for 0.1-10% of the total mass of the nano composition. According to the nano composition disclosed by the invention, the hydroxyl pinacolone retinoate, the nicotinamide and the glycyrrhizic acid are wrapped in the nano composition, so that the stability of functional components is effectively improved. The three functional components of the nano composition are reasonably matched and synergistically interacted, penetrate through a skin barrier and enter deep skin tissues, the bioavailability is improved, the anti-aging, acne-removing and whitening effects are improved, and the nano composition is mild and non-irritant to skin and can be widely applied to cosmetics.

Aerogel compositions that include polyamic amides, methods for preparing the aerogel compositions, and articles of manufacture that include or manufactured from the aerogel compositions are described.

A method is provided for increasing the permeability of skin or mucosal tissue to topically or transdermally administered pharmacologically or cosmeceutically active agents. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the active agent through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. Topically applied formulations and drug delivery devices employing hydroxide-releasing agents as permeation enhancers are provided as well.

Disclosed are methods, compositions, reagents, systems, and kits to prepare nitroxide-functionalized brush-arm star polymer organic radical contrast agent (BASP-ORCA) as well as compositions and uses thereof. Various embodiments show that BASP-ORCA display unprecedented per-nitroxide and per-molecule transverse relaxivities for organic radical contrast agents, exceptional stability, high water solubility, low in vitro and in vivo toxicity, and long blood compartment half-life. These materials have the potential to be adopted for tumor imaging using clinical high-field 1H MRI techniques.

A process for producing a resin-coated pigment capable of providing an ink and a paint being superior in dispersion stability of a pigment and having rapid drying property, high gloss and density without containing those such as an organic solvent and a salt that cause the lowering of performance of pigment dispersion, characterized in that a pigment is dispersed in an aqueous solution in which an anionic group-containing resin is dissolved in the presence of a basic compound and then, the anionic group-containing resin is precipitated on the surface of the pigment by removing the basic compound in the aqueous solution, using an ion exchange means.

An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and sponges. The composition includes macrosize or submicron particles of silver, platinum with silver and their salts with parabens, oxide, salicylate, acetate, citrate, benzoate and phosphate along with copper and zinc salts of the same.

There are disclosed a method for separating a liquid mixture in which a permeation performance enhances, and a composition of the liquid mixture containing a hydrocarbon liquid and an alcohol liquid at supply and a composition after membrane permeation are changed by a separating operation, and a device for separating a liquid mixture. The liquid mixture containing the hydrocarbon liquid and the alcohol liquid is used as a supply mixture liquid, and at least part of the supply mixture liquid is, in a liquid state, brought into contact with a membrane supply side of a separation membrane, and discharged in a vapor state through a membrane permeation side of the separation membrane, whereby a composition of a mixture vapor which is balanced with the supply mixture liquid becomes different from a composition of a vapor on the membrane permeation side.

The present invention addresses the problem of providing a (porous support)-(zeolite membrane) assembly which can achieve both practically sufficient throughput and separation performance in a separation / concentration procedure with a zeolite membrane. The present invention relates to a (porous support)-(zeolite membrane) assembly comprising a porous support and a zeolite membrane formed on the porous support, wherein portions of the zeolite membrane are projected into the porous support and the average of the distances from the surface of the porous support to the inside parts of the zeolite membrane-projecting portions in the porous support is 5.0 [mu]m or less.