The invention relates to an X65 hot-rolled coil for use in an acidic environment and a manufacturing method thereof. The X65 hot-rolled coil comprises the following components by weight percent: 0.02-0.06 weight percent of carbon, 0.15-0.25 weight percent of 
silicon, 0.80-1.20 weight percent of 
manganese, 0.02-0.05 weight percent of 
niobium, 0.020-0.040 weight percent of 
vanadium, 0.010-0.020 weight percent of 
titanium, less than or equal to 0.30 weight percent of 
copper, less than or equal to 0.30 weight percent of 
nickel, 0.10-0.30 weight percent of Cr, less than or equal to 0.015 weight percent of 
phosphorus, less than or equal to 0.0015 weight percent of 
sulfur, 0.0020-0.0050 weight percent of 
calcium, more than or equal to 2.0 weight percent of Ca / S, less than or equal to 0.0005 weight percent of 
boron and less than or equal to 0.006 weight percent of 
nitrogen. Other components are ferrum and trace impurities. The 
steelmaking process 
route and key control points are hot 
metal pretreatment, converter 
steelmaking, LF furnace refining, RH furnace refining, slab 
casting, billet finishing and storage. The refining procedures outside the furnaces comprise Ca treatment to modify inclusions. The key points of the rolling process are as follows: the 
heating temperature is 1150-1200 DEG C, the rough rolling outlet temperature is 920-1020 DEG C, the final rolling temperature is 780-860 DEG C, and the rolling temperature is 560-620 DEG C. The invention adopts low-price 
alloy (Cr and V) to substitute expensive 
alloy (Mo and Nb) so as to produce steel hot-rolled coils for X65 pipelines with more stable performance and lower 
alloy cost. Moreover, the hot-rolled coils for X65 pipelines have anti-HIC performance, high strength and high 
toughness.