Method for synthesizing nonspherical polymer microparticles

[0036] Synthesis of meniscus-shaped polymer particles using figure 1 chips shown, see the actual figure 2 , use a syringe pump to continuously perfuse mineral oil into reservoir A1, continuously perfuse 33% PEGDA aqueous solution (containing 4% tween20 and 1.5 mg / ml photoinitiator) into reservoir B2, and continuously perfuse Fc40 into reservoir C3 (containing 2% EA); oil-in-water droplets (mineral oil / 33% PEGDA aqueous solution) continuously formed at position i, and flowed along the channel through position ii, forming a mononuclear double emulsion at position ii (mineral oil / 33% PEGDA aqueous solution / Fc40); when the formed double emulsion flows through the ultraviolet lamp irradiation area, the 33% PEGDA aqueous solution undergoes a polymerization reaction to form a gel (see image 3 and Figure 4 ); due to the quenching effect of oxygen on free radicals, the polymerization reaction of PEGDA at the Fc40 interface was inhibited, forming an unpolymerized thin layer, resu...

[0038] The synthesis of polymer microparticles with many-legged morphology adopts the method described in Example 1 to adjust the flow velocity of the internal phase, the middle phase and the external phase to form triple-nuclear, quadri-nuclear and penta-nuclear double emulsions respectively (see Figure 8 (a)-(c)), under UV light, polymer microparticles with uniform distribution of tripods, tetrapods and pentapods were formed (see Figure 8 (d)-(j)).

[0040] Synthesis of magnetic polymer microparticles and investigation of their magnetic response, PEGDA, magnetic nanoparticle aqueous solution (9.2% Fe 3 o 4 ) and pure water according to the ratio of 4:2:4 (volume ratio) to make a solution of 10 ml, add Tween20 (4%) and photoinitiator (final concentration is 1.5 mg / ml), the mixed solution is used as the intermediate phase, the internal Phase and external phase are mineral oil and Fc40 (containing 2% EA) respectively, according to the method described in embodiment 1, form non-spherical magnetic polymer microparticles (see Figure 9 (a)). The elemental analysis spectrum shows that the polymer microparticles contain Fe (see Figure 9 (b)), and the magnetic microparticles have a magnetic response and can be attracted by a magnet (see Figure 9 (c)). The synthesized magnetic polymer microparticles are dispersed on the interface of water and Fc40, and then a parallel external magnetic field is applied, and the magnetic polyme...