136 results about "Dysuria" patented technology

The present invention relates to a pharmaceutical composition for treatment and / or prevention for urinary diseases comprising a lysophosphatidic acid (LPA) receptor regulator.As LPA receptor regulators act on urethra and prostate, compounds acting on this receptor are useful in treating urinary diseases (urinary incontinence, dysuria, etc.). For example, an LPA receptor agonist useful for treatment of urinary incontinence, while an LPA receptor antagonist is useful for treatment of dysuria, ischuria, pollakiuria, nocturia, urodynia and benign prostatic hyperplasia.

A crystal for oral solid medicament comprised of indoline compound (KMD-3213) which exerts α1-adrenaline receptor blocking effect, is useful as a therapeutic agent for dysuria and is represented by the formula: (I) wherein in the powder X-ray diffraction pattern, the compound is characterized by main peaks of 5.5°±0.2°, 6.1°±0.2°, 9.8°±0.2°, 11.1°±0.2°, 12.2°±0.2°, 16.4°±0.2°, 19.7°±0.2° and 20.0°±0.2° as 2θ. There is further provided an oral solid medicament for dysuria treatment containing the crystal as an active ingredient.

The invention discloses quinoxaline derivatives or salts thereof having PDE9-inhibiting activity and being useful as treating agent of dysuria and the like, which are represented by the formula (I)in the formula,R1 and R2 each independently stands for hydrogen, halogen, alkyl, alkoxy, acyl, amino and the like,R3 stands for alkyl, aryl, saturated carbocyclic group, saturated heterocyclic group, acyl and the like,R4 stands for hydrogen, hydroxy, alkyl or amino,R5 and R8 each independently stands for hydrogen, halogen, alkyl, alkenyl, alkoxy, cyano or nitro,R6 and R7 each independently stands for hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxy, cyano, amino, carbocyclic group, heterocyclic group, COR9 or SO2R9,R9 stands for hydrogen, hydroxy, alkyl, amino, pyrrolidin-1-yl, piperidin-1-yl, pyperazin-1-yl or the like,X stands for S or O, andA1, A2 and A3 each independently stands for N or C.

The invention discloses a double-balloon catheter stent, which is composed of a positioning balloon and a columnar balloon, wherein the columnar balloon is a double-layer balloon, the inner layer balloon is made of a material with a pressure greater than 0.5MPa, and the outer layer balloon The material is one of soft polyurethane, latex or silica gel, the surface of the columnar balloon is equipped with a stent, and the surface of the stent is coated with a hydrophilic coating material. The invention is used for placing a bracket in a lumen, and is especially suitable for placing a bracket in the urethra in urology as a temporary support for patients with dysuria, replacing a urinary catheter.

Disclosed is a treating agent of overactive bladder syndrome, pollakiuria, urinary incontinence, dysuria in benign prostatic hyperplasia or urolithiasis, which comprises a compound having PDE9-inhibiting activity as the active ingredient.

The conventional anticholinergic drugs for administration through inhalation have been considered to have the possibility of aggravating dysuria associated with prostatic hyperplasia mediated by blood, and it has been demanded that the conventional anticholinergic drugs for administration through inhalation will have to show reduced side effects or adverse reactions. The present invention relates to a compound represented by the general formula (I): (wherein A represents; and R1, R2, R3 and R1 each a hydrogen atom or a substituent; R5 is a substituent; X− is an anion; the symbol: denotes an exo-form or endo-form, or their mixture), its salt or solvation product thereof. They are useful as a prophylactic and / or therapeutic agent with reduced side effects or adverse reactions for the diseases mediated by the muscarinic receptor.

The invention discloses an antioxidant health food beneficial to male prostatitis. The health food is prepared from the following raw materials in parts by weight: 0.1-1 part of lycopene, 1-5 parts of rape flower pollen, 0.1-1 part of a turmeric extract and 0.005-0.01 part of a natural vitamin E. The antioxidant health food beneficial to male prostatitis is capable of directly or indirectly improving symptoms such as frequent micturition, enuresis nocturna, urgent urination, urinary incontinence, dysuria, incomplete urination and residual urine increase; natural extracts are selected according to the theoretical research of modern pharmacology and drug efficacy and actual efficacy research of various raw materials; and the antioxidant health food is safe, non-toxic and obvious in antioxidant effect.

The invention provides double-layer osmotic pump tablets of tamsulosin ehydrochloride and a process for preparation. The medicament contains tamsulosin ehydrochloride and acceptable medical polymeric excipient, and is characterized in that the invention has excellent zero-level controlled releasing, pH level of environment, movements of the stomach and intestine, and food, has little effect on releasing action and food, and has no effect on the internal pharmacokinetics parameter. According to the percentage by weight, the preparation contains tamsulosin ehydrochloride 0-2%, excipient in pastille layer with the function of controlled-releasing 30-70% excipient in boosting layer with the function of controlled releasing 30-70%, and the rest percentage of other excipient. The of process for preparation the double layer permeable pump controlled-release tablets of tamsulosin ehydrochloride comprises (1) the preparation of pastille layer, (2) the preparation of boosting layer, (3) the compressing of the two layers, (4) the coating of the double layer tablets, (5) the perforating of the coated tablets, (6) the packing of moisture proof cost. The invention is clinically used for the treatment of paruria symptom like frequent micturition, diuresis at night, dysuria caused by prostatic hyperplasia.

The invention relates to a kind of medical wine that possesses functions of excreting dampness, eliminating arthralgia syndrome, apocenosis and invigorating the spleed and strengthening the middle-warmer energy. It mainly takes coix seed as raw material, and the effect for treating dropsy, asthma, lung abscess, nephritis, nephropyeltis, beriberi, dysuria, arthritis with muscle contracture, diarrhea of deficiency type, acute pharyngitis and flat wart is distinctive. The product can be used as normal health- care beverage, which is non side effect, and possesses good economic and social benefit.

The invention discloses a Chines medicine composition preparation capable of curing renal calculus. The Chines medicine composition preparation capable of curing the renal calculus is mainly composed of fringed pink, spora lygodii, poria cocos, rhizoma alismatis, grifola, longhairy antenoron herb, plantain seeds, radix cyathulae, myrrh and qizzard pepsin. The Chines medicine composition preparation capable of curing the renal calculus has effects of diuresis inducing and strangurtia treating, has good treatment effects of pain, dark urine, dysuresia caused by the renal calculus and capable of effectively and fast curing the renal calculus. The Chines medicine composition preparation capable of curing the renal calculus is ideal and safe medicine capable of curing the renal calculus.

The invention discloses kidney-warming, yang-strengthening and health-preserving medicinal liquor and a preparation method thereof. The preparation method comprises the following steps: (1) preparing the liquor: decocting seal kidney, cistanche, Zhihaima, ginseng, etc in water for 30min and isolating 5000ml of liquor and the dregs for later use; (2) mixing: cooling husked sorghum thoroughly (cooling), pouring the dregs and liquor obtained in the step (1) together with Huaiqu into a fermentor, stirring the mixture with a willow stick uniformly and sealing the fermentor; and (3) fermenting: placing the mixture obtained in the step (2) and the fermentor into a cellar, taking out the mixture and the fermentor out of the cellar and unsealing the fermentor after 100 days, filtering the mixture to remove the dregs and adding crystal sugar, standing for seven days and subpackaging the warehousing the liquor after all the crystal sugar is dissolved. The medicinal liquor has rich color, sweet taste and strong aroma and has good treatment and prevention effects on impotence and premature ejaculation, nocturnal emission and spermatorrhea, dysuria, soreness and acratia, kidney deficiency and coldness, limb asthenia, prostatic hyperplasia and other morbid symptoms.

The invention relates to an application of ergot sterone in preparation of diuresis medicine. Polyporus umbellatus crude drug is mainly used for clearing damp and promoting diuresis and treating dysuria, edema, diarrhea, strangury with turbid urine and morbid leucorrhea. The inventor utilizes diuresis as pharmacological index and screens target area and active ingredients identical with the function of the polyporus umbellatus on the basis of chemical ingredient research on the polyporus umbellatus. Normal saline loaded water retention animal model is adopted for diuresis screening on sterides compound therein, and the ergot sterone is found to have better diuresis effect and is determined as the target area of diuresis of the polyporus umbellatus.

The invention relates to the field of health foods and particularly relates to a preparation method of a tea bag for alleviating hangover, helping digestion and protecting liver. The preparation method comprises the following steps of: packaging a rhizoma imperatae extractive and a fructus schisandrae extractive by lotus leaves to obtain a mixture, adding fringed pink, lemon slices and jasmine flowers into the mixture, and bagging. According to the preparation method of the tea bag for alleviating the hangover, helping the digestion and protecting the liver, invalid impurities of the rhizoma imperatae extractive and the fructus schisandrae extractive are removed, the use quantities of the rhizoma imperatae extractive and the fructus schisandrae extractive are reduced, and active substances are easily dissolved and absorbed, and the taste is relatively good. The extractives are packaged by the lotus leaves, the deliquescence of the extractives can be reduced, and the extractives can be prevented from being contacted with other medical materials and packaging materials after the deliquescence. The lotus leaves have good digestion helping and fat reducing functions, and the smell of the lotus leaves is fragrant. The fringed pink has the effects of reducing fever and causing dieresis and assisting rhizoma imperatae to be excreted from a water channel. The lemon slices and the jasmine flower assist the fructus schisandrae to smooth the liver, regulate vital energy and enhance the fragrance. The functions of hangover alleviating, digestion helping, liver protection and kidney tonifying are entirely considered, and the tea bag is very suitable for being drunk after the meal. The tea bag has a good healthcare effect after being drunk in normal times and can be used for assisting treatment on diseases such as alcoholic liver, fatty liver, hepatitis, hyperlipaemia, fat, dysuria, and edema.

The present invention relates to a compound having a highly selective Rho-kinase inhibiting activity and being useful as a therapeutic agent for a disease such as hypertension, pulmonary hypertension, cerebral vasospasm, cardiac angina, cardiac failure, arteriosclerosis, glaucoma, dysuria, asthma, or erectile dysfunction, and a drug containing the compound.Provided is a homopiperazine derivative represented by General Formula (1), an acid addition salt thereof, or a solvate of the derivative or the salt:(wherein R1 represents an amino acid residue; R2 represents a hydrogen atom or an alkyl group; R3 represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, an alkoxy group, a halogen atom, a nitrile group, or a hydroxyl group; and R4 represents a hydrogen atom, a halogen atom, or a hydroxyl group).

A preventive and / or therapeutic agent for dysuria, which comprises as an effective ingredient a cyclohexenone long-chain alcoholic derivative represented by the following formula (1): [wherein, R1, R2 and R3 each independently represents a hydrogen atom or a methyl group and X represents a linear or branched C10-28 alkylene or alkenylene group]. This compound alleviates dysuria due to hypofunction of the urinary bladder so that they are useful as a preventive and / or therapeutic agent for dysuria

The invention discloses a health care beverage for preventing and resisting cancers, which is characterized by comprising the following substances in parts by weight: 35-50 parts of fig, 18-42 parts of bamboo fungus, 10-22 parts of asparagus, 0.5-5 parts of selaginella doederleinii hieron, 8-18 parts of honey, 5-8 parts of xylitol, 0.5-4 parts of citric acid and 0.2-0.5 part of essence. The product provided by the invention can prevent the protein synthesis of cancer cells in the human body, prevent the cancer cells from diffusing, enable the cell growth to reach normalization, has the efficacies of preventing cancers, resisting cancers and viruses and enhancing the immunocompetence after being frequently drunk, has a certain curative effects on symptoms of heart disease, hypertension, tachycardia, apocamnosis, hydroncus, cystitis, dysuresia, and the like at the same time and has a broad market prospect.

The invention provides a compound for the treatment or prophylaxis of pathology involving SNS, specifically diseases such as neuropathic pain, nociceptive pain, dysuria, multiple sclerosis and the like. The compound is represented by formula (1) or a pharmaceutically acceptable salt thereof wherein R1 is a hydrogen atom or the like, L is a single bond, —O— or the like, R2 is a phenyl group or the like, X is a carbon atom or a nitrogen atom, and R3, R4, R5a, R5b, R6 and R7 are each independently a substituted or unsubstituted alkyl group or the like:

The invention provides external medicine for treating toothache. The medicine is characterized by consists of the following raw material medicine in weight: 25g of alum and 120g of fresh snakeweed. A preparation method of the medicine comprises the following steps that: the alum is crushed and is screened by a sieve being 80 meshes, the snakeweed is cleanly washed, the alum and the snakeweed are uniformly mixed and are mashed into juices to be dripped into the auditory meatus. The medicine has the efficacies and beneficial effects that the alum is cold in property and is acerb in taste, a strong convergence effect is realized, and the efficacies of eliminating toxin, killing intestinal worms, removing dampness, relieving itching, stopping bleeding, stopping diarrhoica, clearing away the heat and dissolving the phlegm are realized. The alum also has antibacterium effect, anti-trichomonas-vaginalis effect and the like. The snakeweed has the effects of clearing away the heat, realizing diuresis, cooling the blood and eliminating the toxin. The medicine mainly treats heat accumulation of the bladder, dysuria, leucorrhea, summer damp diarrhea, nosebleed, hematuria, liver heat and hot eyes, swelling and pain in throat and swollen welling-abscess toxin and has the anti-inflammatory effect. The external medicine has the advantages that the preparation is simple, the side effect is small, and the external medicine is applicable to various kinds of toothache.

The invention discloses a medicament for curing dysuria, a preparation method and a quality control method thereof. The medicament is prepared by mainly using the following raw materials in part by weight: 240 to 360 parts of semen psoraleae, 360 to 560 parts of leonurus, 240 to 360 parts of spora lygodii and 180 to 300 parts of tulip bulb. In the quality control method, a plurality of medicinal materials in the product are controlled by an HPLD method and a TLC method. The medicament, the preparation method and the quality control method thereof have the advantage that: a clinical experiment shows that the effective rate of an experimental group is 98.85 percent and the effective rate of a control group is 96.92 percent. Due to dried powder directly used as medicament, the best concentration proportion and a specific drying condition, the process can be controlled better compared with the process of using clear paste as medicament.

The invention belongs to the technical field of medicine, and particularly relates to a medicament for treating prostatic hyperplasia. Major active ingredients are polysaccharides extracted from Vaccaria segetalis (Neck.) Garcke serving as caryophyllaceae plants. The polysaccharides are from seeds of the Vaccaria segetalis (Neck.) Garcke. A method for preparing the polysaccharides of the Vaccariasegetalis (Neck.) Garcke and the medicinal composition of the polysaccharides of the Vaccaria segetalis (Neck.) Garcke is simple and effective, and the polysaccharides of the Vaccaria segetalis (Neck.) Garcke and the medicinal composition of the polysaccharides of the Vaccaria segetalis (Neck.) Garcke can be prepared into various common oral formulations of solid, liquid and the like. The medicament is mainly used for treating the prostatic hyperplasia and frequent micturition, urgent urination, odynuria and dysuresia which are caused by the prostatic hyperplasia. Compared with the conventional medicament, the medicament for treating the prostatic hyperplasia is obvious and quick in curative effect, low in relapse rate and stable and controllable in quality, and does not have any toxic orside effect.

The invention discloses a quality detection method for Chinese patent medicine dysuria remedying granules for treating chronic prostatitis. The quality detection method comprises the steps that the thin layer chromatography is adopted for recognizing cinnamon, Chinese violets, radix scrophulariae, golden cypress, radix sophorae flavescentis, rhizoma dioscoreae hypoglaucae and radix cyathulae in the preparation, and meanwhile HPLC is adopted for determining the content of berberine hydrochloride of the golden cypress in the preparation and the content of amygdalin in peach kernels. The quality detection method is stable, reliable, high in specificity, good in reproducibility, capable of comprehensively and effectively controlling the quality of the dysuria remedying granules, and capable of stabilizing the product quality, ensuring the clinical medication safety and effectiveness and better meeting the requirement for medical treatment and market.

The invention relates to a thermoplastic forming method of an implantable flexible magnetic control bladder pump. The thermoplastic forming method comprises the following steps of preparing a ferromagnetic complex from organic silica gel, polydimethylsiloxane resin and magnetic particles; preparing a hot-melt-state flexible non-magnetic substrate from organic silica gel, polydimethylsiloxane resin and a brightener; and carrying out injection molding, curing and forming on the hot-melt-state flexible non-magnetic matrix and the ferromagnetic complex, so that the implantable flexible magnetic control bladder pump is manufactured. The implantable flexible magnetic control bladder pump prepared through the thermoplastic forming method can effectively and permanently solve dysuria diseases such as nerve type bladder dysfunction and the like, and after the flexible magnetic control bladder pump is implanted through an operation, the normal urination function can be realized through high torque of magnetic field force applied by an external magnetic field under the condition of not connecting any additional pipeline.

The invention discloses a traditional Chinese medicine for treating lung heat congestion type dysuria. The traditional Chinese medicine is characterized by being prepared from the following medicinal materials in parts by weight: 10 parts of cortex lycii radicis, 12 parts of blumea, 10 parts of walton's lepisorus, 12 parts of pumice, 8 parts of Chinese lobelia, 12 parts of bretschneider pear pericarp, 12 parts of adenophora tetraphylla, 20 parts of rhizoma phragmitis, 10 parts of triglochin martimum, 20 parts of gypsum rubrum, 15 parts of dodonaea viscosa leaf, 25 parts of Japanese raspberry root, 20 parts of splendid achnatherum, 20 parts of palmate maidenhair, 10 parts of cayratia japonica, 20 parts of primula hypoleuca, 20 parts of wild rice root, 10 parts of omei mountain bamboo juvenile leaf and 6 parts of licorice. According to the traditional Chinese medicine disclosed by the invention, the medicinal materials are organically combined and mutually cooperate to ensure the functions of dispersing blood stasis, removing stasis and inducing diuresis; the traditional Chinese medicine can be used for effectively treating blood stasis interior obstruction uroschesis; over the past years, as shown in application of patients, the effective rate reaches 98.3%; the traditional Chinese medicine takes effect quickly and can generally take effect on the second day after being used, the patients can be healed within 6-10 days according to the conditions of the patients, the cure rate is high, and no relapse has been found in follow-up visit after cure of 2 months.

The invention relates to a thermoplastic forming mold of an implantable flexible magnetic control bladder pump. The bladder pump comprises a mold core, a front mold box, a rear mold box, a front mold box insertion block group and a rear mold box insertion block, wherein the mold core is composed of a mold core main body and a mold core handle; the shape of the mold core main body is matched with the shape of a filled bladder; the shape of the mold core handle is matched with the shape of a urethra connected with the bladder; the top of the front mold box is provided with a plurality of insertion grooves matched with the front mold box insertion block group; a front mold containing cavity is formed in the front mold box; an insertion hole matched with the rear mold box insertion block is formed in the top of the rear mold box; a rear mold containing cavity is formed in the rear mold box; and the mold core handle is arranged in the rear mold containing cavity. The implantable flexible magnetic control bladder pump prepared by the thermoplastic forming mold can effectively and permanently solve dysuria diseases such as nerve type bladder dysfunction; and after the flexible magnetic control bladder pump is implanted through an operation, the normal urination function can be realized through high torque of magnetic force applied by an external magnetic field under the condition that no additional pipeline is connected.

The invention provides an oral solution for curing dysuria, which takes silodosin as main active ingredient or silodosin prodrug or pharmaceutically acceptable salt. The oral solution, which is made of water, ethanol or the mixture of the two, overcomes the defects of difficult taking, slow dissolving out and low biological utilization rate in tablet, capsule and other solid preparations. With stable fluid quality, the oral solution has excellent compliance and biologic utilization rate and can be best taken by elder patients.

The invention discloses a medicine composition which is mainly prepared from desmodium styracifolium, asiatic centella, oldenlandia diffusa, milk veteh, pyrrosia lingua, lygodium japonicum and giant knotweed. The medicine composition has the efficacy of clearing away heat and toxic materials as well as removing dampness and treating stranguria, and is used for stranguria, difficulty and pain in micturition and urinary tract infection which are caused by damp heat accumulation; and the adaptation diseases include frequent urination, urgent urination, dysuria, dark yellow urine and urinary tract infection. The medicine composition can be prepared into various oral liquid.

The invention discloses soybean milk containing snake gourd fruit leaves. The soybean milk is characterized by comprising the following raw materials in parts by weight: 65-75 parts of soybeans, 10-12 parts of green beans, 6-10 parts of peanuts, 10-14 parts of glutinous rice, 6-10 parts of oat, 2-4 parts of pumpkin flowers, 1-2 parts of rehmannia glutinosa (gaertn.) libosch, 1-2 parts of Indian buead, 1-2 parts of isomaltulose, 1-2 parts of snake gourd fruit leaves, 0.6-0.8 part of fresh milk essence, 0.3-0.5 part of soybean oil, 0.2-0.3 part of distilled monoglyceride and a proper amount of water. The soybean milk has the advantages that the soybean milk is converted from a single soybean milk edible to an edible with health care functionality at the same time; the added Indian bread has the functions of excreting dampness, inducing diuresis, strengthening the spleen and stomach and calming hearts and the nerves and can be used for treating such symptoms as dysuria, swelling due to edema, choking cough due to phlegm and retained fluid, vomiting, pernicious vomiting, diarrhea, spermatorrhea, stranguria with turbid discharge, palpitation and forgetfulness; the added rehmannia glutinosa (gaertn.) libosch has the functions of treating diabetes and lumbar pain due to kidney asthenia and the like; and the soybean milk absolutely has the characteristics of engineering functional ingredients, nutrition functional ingredients and prepared food base materials.

The invention provides a method for preparing a traditional Chinese medicine for curing deficiency in heart and spleen depressive psychosis, and the method belongs to the medical appliance technical field. The depressive psychosis adopts the antidepressant medications for patients with pixilation disease and the imipramine therapy and causes the symptoms such as dry mouth, constipation, sweatiness, fremitus, blurred vision and dysuria. The technical proposal of the invention is as follows: the raw medicines of radix codonopsitis, broiled milk veteh, heterophylly falsestarwort root, atractylis ovata, bidens tripartita, malt extract, Chinese date, tuckahoe, angelica, radix paeoniae alba, lungyen pulp, spina date seed, semen biotae shelled, semen biotae shelled, polygala, cortex albiziae, caulis polygoni multiflori, wheat, ulmaceae, cinnamon and liquorice are placed into 1200 milliliters of water to be steeped for 30 minutes and are decocted by slow fire, the decocted liquid medicine is filtered by gauze to eliminate dregs, and 560 milliliters of liquid medicine which is the traditional Chinese medicine for curing deficiency in heart and spleen depressive psychosis is made. The traditional Chinese medicine has the advantages of simple preparation, fewer side effect and low toxicity. After the medicine is taken orally, the medicine can be absorbed in a digestive canal; therefore, the curative effect is stable and is not easy to rebound.