The present invention relates to a 
gelatin / 
biological activity glass compounded 
sponge dressing and a preparation method thereof, belonging to the 
biomaterial field. The dressing is characterized in that a solution of a content of between 1 and 30 percent is prepared with 
gelatin as the 
raw material; the 
biological activity glass 
powder with a weight percentage of between 2 and 20 percent, prepared by the fusion method or the 
sol-
gel method, is put into the solution; and then a 
mixed solution is obtained by magnetic stirring. The 
mixed solution is poured into a mould, the 
liquid layer is up to between 1 and 8 mm, the 
mixed solution is kept stand for 0.5 to 3 h, and then the prefreezing temperature is controlled between 20 DEG C below zero and 80 DEG C below zero; the lyophilization is controlled to be carried out at a temperature of 40 DEG C below zero and a pressure of between 5 and 10 KPa. The section of the present invention is of a double layer 
composite structure with a thickness of between 0.5 and 5 mm, wherein, the upper layer is a loose 
porous layer, and the lower layer is a dense 
powder layer, the thickness of the 
powder layer being up to between 0.1 and 2.0 mm. The double layer 
sponge dressing is flexible, which can be used as a 
parenchyma wound restoring material. Particularly, the double 
sponge dressing is suitable for any one of 
parenchyma ulcers of 
cervix erosions, 
oral ulcers, bedsores, sinuses, fat liquescency wounds, venereal 
disease ulcers, 
hemorrhoids, diabetes ulcers, etc. and the long-term erosions thereof.