745 results about "Glucic acid" patented technology

The present invention relates to a polysaccharide having functional groups, wherein said groups are aldehyde groups formed at positions C2 and / or C3 as well as at position C6 of the anhydroglucose units of the polysaccharide chain. Preferably the polysaccharide is a cellulosic fibrous material whose primary and secondary hydroxyl groups of the cellulose are oxidized into aldehyde groups at least in part by means of TEMPO oxidation and periodate oxidation.The invention also concerns a paper or nonwoven comprising the above polysaccharide. According to the invention a relative wet strength of more than 10% can be achieved.

The present invention generally relates to processes for the chemocatalytic conversion of a glucose source to an adipic acid product. The present invention includes processes for the conversion of glucose to an adipic acid product via glucaric acid or derivatives thereof. The present invention also includes processes comprising catalytic oxidation of glucose to glucaric acid or derivative thereof and processes comprising the catalytic hydrodeoxygenation of glucaric acid or derivatives thereof to an adipic acid product. The present invention also includes products produced from adipic acid product and processes for the production thereof from such adipic acid product.

The invention relates to a composite probiotics feed additive containing lactic acid bacteria. The composite probiotics feed additive is prepared by spraying, freezing, drying and compounding 40-60% of lactobacillus acidophilus, 15-20% of lactobacillus amylophilus, 5-10% of lactobacillus salivarius, 5-10% of streptococcus thermophilus, 5-10% of bacteroides thetaiotaomicron and 5-10% of glucose. All strains are separated from pig intestines chime. With the consideration of each part of an intestinal canal of animal, the lactic acid bacteria which produce lactic acid of the front section of the intestinal canal are combined with the bacteroides thetaiotaomicron which dissolve cellulose and polysaccharide of the rear section of the intestinal canal, the proportion among the bacteria is similar to the composition of corresponding bacteria in the intestinal canal of a healthy animal, so that the respective advantages can be developed well, the health of the animal is improved further, the feed digestibility is improved, and the production performance of the animal is improved.

The invention discloses a micro capsule of lactic acid bacteria and its preparation, wherein the micro capsule includes a core material of lactic acid bacterium particles, the bolus making auxiliary material being one or more selected from cane sugar, maltose dextrin, crystalline cellulose, maize starch, glucose or protein sugar, and the wall material comprises sodium acetylide and CaCl2, carrageenan, soybean separated albumen powder, and water-insoluble plant oil.

Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a fatty component containing at least one free hydroxyl group, such as a C12-C21 fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C21 fatty amide, and combinations thereof; and optionally an emollient ester such as diesters of bibasic acids and triesters of citric acid. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.

This invention provides novel enzyme compositions using newly identified and isolated C. lucknowense enzymes, including CBH Ib CBH IIb, EG II, EG VI, β-glucosidase, and xylanase II in conjunction with previously identified enzymes CBH Ia, CBH IIa (previously described as Endo 43), and EG V. These enzyme compositions demonstrate an extremely high ability to convert lignocellulosic biomass (e.g., Avicel, cotton, Douglas fir wood pretreated by organosolv) to glucose. CBH Ia and IIb, which both have a cellulose-binding module (CBM) displayed a pronounced synergism with three major endoglucanases (EG II, EG V, EG VI) from the same fungus in hydrolysis of cotton as well as a strong synergy with each other. The enzyme compositions are effective in hydrolysis of the lignocellulosic biomass.

The present invention has objects to provide an extract powder of indigo plant, which has a relatively low hygroscopicity, satisfactory fluidability, and improved storage stability; a process thereof; and a composition incorporated with the extract powder. The objects are solved by a process for producing an extract powder of indigo plant, which comprises incorporating a partial starch hydrolyzate with a dextrose equivalent of 10.2 or lower into one part by weight, on a dry solid basis, of an indigo plant extract contained in a liquid extract of indigo plant in an amount of not lower than 0.25 part by weight but not higher than 5 parts by weight, on a dry solid basis, and drying the resulting mixture; an extract powder of indigo plant prepared thereby; and a composition incorporated with the extract powder.

The invention discloses novel N-acetylneuraminic acid-producing escherichia coli engineering bacteria as well as a construction method and application thereof. The engineering bacterial is constructed by introducing an encoded 6-glucosamine phosphate acetylase gene, an N-acetyl glucosamine-2-isomerase gene and an N-acetylneuraminic acid synthetase gene into escherichia coli to express, carrying out strengthened expression on 6-glucosamine phosphate deaminase gene contained in the escherichia coli per se and knocking off genes, for decomposing and utilizing enzyme in metabolic pathways, of the N-acetylneuraminic acid in the engineering bacteria. The engineering bacteria disclosed by the invention can be used for fermentation culture to synthesize the N-acetylneuraminic acid by using glucose or glycerinum as a substrate.

The present invention herein provides a chitosan-containing polysaccharide and a method for the preparation thereof as well as a medicine and a food containing the polysaccharide.The chitosan-containing polysaccharide is prepared by a method comprising the steps of heat-treating a fungus in a concentrated aqueous caustic alkali solution; subjecting the resulting solution to a solid-liquid separation treatment; dissolving the resulting solid contents in an aqueous organic acid solution; adding, to the resulting solution, an alcohol or a caustic alkali to thus form precipitates; washing the resulting precipitates; and then drying them. This chitosan-containing polysaccharide is a compound in which homopolymers of glucosamine are linked with glucan through covalent bonds; it has a molar ratio of glucosamine and glucose constituting the polysaccharide ranging from 1:5 to 5:1; it has a molecular weight of about 150,000; and it does not contain any β(1→3) bonds, but comprises β(1→4) bonds and β(1→6) bonds. The polysaccharide is free of any protein and reducing polysaccharide. The chitosan-containing polysaccharide is effective for the treatment or prevention of any diseases originated from living habits or customs such as hypertension and diabetes.

Disclosed are methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis, the methods comprising administration of substituted indolealkanoic acids to patients in need of such treatment. Also disclosed are such compounds useful in the treatment of angiogenesis, hyperglycemia, hyperlipidemia and chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds. Further, disclosed are combinations of an angiotensin converting enzyme inhibitor and a substituted indole acetic acid.

The invention discloses a method for increasing enzymolysis efficiency of rice straws through choline and amino acid ionic liquid pretreatment, which comprises the following steps: firstly, performing pretreatment on the rice straws at certain temperature for a certain period of time by taking choline and amino acid ionic liquid as a solvent; then filtering and separating to obtain residues; drying the residues to obtain the pretreated rice straws. The residues of the rice straws are used as substrates, and enzymolysis is performed on the substrates by utilizing cellulase and xylanase to finally obtain sugar liquor taking glucose and xylose as main components. The method for increasing the enzymolysis efficiency of the rice straws through the choline and amino acid ionic liquid pretreatment not only is capable of effectively increasing the enzymolysis efficiency of the rice straws and increasing the yield of reducing sugar (the glucose and the xylose) which can be fermented, but also is capable of overcoming the defects that a traditional ionic liquid pretreatment process environment is not friendly and the like.

Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a fatty component containing at least one free hydroxyl group, such as a C12-C21 fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C21 fatty amide, and combinations thereof; and optionally an emollient ester such as diesters of bibasic acids and triesters of citric acid. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.

Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a hydrophobic polymer soluble in the lower alcohol; an emollient ester such as diesters of bibasic acids and triesters of citric acid; and an optional fatty component containing at least one free hydroxyl group, such as a C12-C21 fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C21 fatty amide, and combinations thereof. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.

The invention discloses a novel dihydrogen bond deep-eutectic solvent and a method for pretreating rice straws through combination of the solvent and sodium carbonate; straw hydrolysate after enzymolysis can be used for clostridium fermentation to synthesize bio-butanol. The deep-eutectic solvent provided by the invention is the novel dihydrogen bond deep-eutectic solvent which is synthesized by stirring choline chloride, formic acid and acetic acid at a molar ratio of 1:1:1 at the temperature of 30 DEG C; the solvent can be used for reducing the contents of lignin and hemicellulose in a lignocellulose raw material, so that the accessibility of cellulose in the lignocellulose raw material. The solvent and the sodium carbonate are combined to pretreat the rice straws, and enzyme hydrolysisis performed on the pretreated rice straws with cellulose, so as to obtain the hydrolysate containing 4.28g / L of total reducing sugar; the yield of glucose is 80%; in addition, the hydrolysate has noobvious inhibiting effect on the growth of microorganisms such as clostridium and the like, and the yield of butanol is 13.73g.L<-1>. The dihydrogen bond deep-eutectic solvent is an environment-friendly solvent which is simple in synthesis and convenient to use and has good application and development prospects in pretreatment of the lignocellulose raw material.

The invention discloses a bacterial cellulose compound cuprous oxide antimicrobial dressing and a preparation method thereof. The bacterial cellulose compound cuprous oxide antimicrobial dressing lies in that cuprous oxide particles are adhered into a three-dimensional porous network structure of a bacterial cellulose hydrogel film, the cuprous oxide particles are of octahedral crystal forms, and the antimicrobial dressing is obtained by soaking a bacterial cellulose hydrogel film containing a glucose solution into a NaOH water solution and copper ion water solution mixed solution and heating and pressurizing for reaction. The bacterial cellulose compound cuprous oxide antimicrobial dressing is simple and convenient in preparation process and low in cost, has not only excellent bacteria resistance but also the advantages of high water content, good air permeability, excellent degradation property, no cytotoxicity and the like, and can well meet the demand of wet-process treatment for various wounds.

The invention relates to a method for extracting xylose from viscoce chemical fiber squeezed alkali liquor. According to the technical scheme, the method comprises the following steps: pre-filtering to obtain pre-concentrated liquor; filtering the pre-concentrated liquor through a nanofiltration membrane to obtain concentrated liquor; adding hydrochloric acid to the concentrated liquor to obtain hydrolysate; adding hydrolysate to NaOH until being neutral; decolorizing; regulating the concentration of NaCl; cooling at constant speed until reaching room temperature; enabling glucose in hydrolysate to cocrystallize with NaCl to remove glucose; treating filtrate through ion exchange columns to obtain purified liquor; crystallizing and purifying the purified liquor for the second time to obtain coarse xylose; refining the coarse xylose to obtain final xylose. With the adoption of the method, the resource is saved, the economic benefit is brought to enterprises, and the environment is protected.

A composition and method for enhancing brain development in a pediatric subject, the method including administering to the pediatric subject a nutritional composition having up to about 7 g / 100 kcal of a fat or lipid source, wherein the fat or lipid source includes at least about 0.5 mg / 100 kcal of milk or non-milk polar lipids; up to about 5 g / 100 kcal of a protein source; at least about 15 mg / 100 kcal of lactoferrin from a non-human source; about 0.015 g / 100 kcal to about 0.15 g / 100 kcal of a prebiotic composition including polydextrose and / or galactooligosaccharide; and at least about 5 mg / 100 kcal of a source of long chain polyunsaturated fatty acids.

The invention provides a gene engineer strain of Aspergillus niger with high L-malic acid yield and a construction method thereof. The method utilizes gene knockout technique to disrupt the Aspergillus niger oxaloacetic acid hydrolase gene (oahA) so as to obtain the malic acid-producing strain S2. After 7 days of shake flask fermentation, 100 g / L glucose is converted into 120.4 + / - 2. 8 g / L of L-malic acid, the conversion of malic acid and malic acid to glucose is 1.62 mol / mol, which is 81% of the highest conversion in theory. A good strain for the industrialized production of malic acid is provided.

The present invention provides an industry method for producing arachidonic acid grease by using mortierella alpine. The method is characterized by comprising the following steps: activating an original strain; carrying out seed culture; carrying out seed enlarge culture; and carrying out fermentation culture, wherein the fermentation culture comprises an initial fermentation stage, the seed enlarge culture liquid is inoculated in a fermentation tank to carry out stirring culture, glucose and edible oil are supplemented according to the situation, the initial fermentation stage is completed when bacterial concentration of the fermentation broth achieves 40% (by ??volume) and the dried mycelium total oil achieves 40 wt%, a post-fermentation stage starts, the fermentation broth is cooled to a temperature of 23-27 DEG C, sterile ammonia water is concurrently added to adjust the pH value to 8-9, standing fermentation is performed while the glucose content is controlled, the post-fermentation stage is completed when the arachidonic acid content is higher than 45 wt%, and the obtained fermentation broth is subjected to a fermentation treatment to obtain the grease containing the arachidonic acid. The industry method has the following characteristics that: a fermentation formula is simplified, specific yield of the arachidonic acid can be 10 gARA / L fermentation broth through the specific process control, a process is simple and easy to control, and industrial production is achieved.

The invention discloses an astragaloside IV injection preparation (small injection, powder injection, glucose fluid infusion and sodium chloride fluid infusion), and the process for its preparation, wherein the auxiliary solvent and solvent assisting deflocculating agent are screened, which has proved that propylene glycol, ethanol, glycerin, polyethylene glycol, benzyl benzoate and acetic acid dimethylamide has solubilization function for astragaloside IV.

Disclosed are compositions, including low-calorie beverages or liquids, comprising isoleucine, leucine, valine, cysteine, and methionine, in specified amounts, weight ratios, or both. The compositions are especially useful in treating individuals afflicted with impaired glucose tolerance or diabetes.

The present invention is a compound represented by the following formula (1) or (2): where one of R1 and R2 is hydrogen and the other one is hydrogen or glucose residue. The compound is effective for reforming obese constitution, suppressing or preventing obesity. It is also effective for skin whitening.

The invention provides a method for preparing mixed immobilized glucose oxidase (GOD) / catalase (CAT) microspheres and belongs to the technical field of immobilized enzyme. The method comprises the following steps: on the basis of using chitosan-arginine anionic microspheres as carrier, adding a mixed solution of GOD and CAT and glutaraldehyde, performing crosslinking reaction, filtering, washing,and performing freeze drying to prepare mixed immobilized GOD / CAT microspheres. The method has the characteristics of mild reaction conditions, higher recovery rate of enzyme activity, long half-lifeof immobilized enzyme, simplicity in operation, low cost, cleanness, safety, and the like. The product prepared by the method can be widely used in the industries of medicines, food, water treatment,cement and the like. The product can also be used as a glucose-removing reagent, an anti-oxidation reagent, a bactericide, a glucose quantitative analysis reagent and the like.

The invention provides a micro-fluidic paper chip for simultaneously detecting glucose, uric acid, triglycerides and cholesterols, and its manufacturing method. The paper chip is a novel personalized diagnosis device, can rapidly, cheaply and simply detect multiple components without instrument equipment or professional people, can be operated by a patients or their families, and can momentarily and rapidly detect the concentrations of the glucose, the uric acid, the triglycerides and the cholesterols in blood.

The invention discloses a preparing method of natural peel acid with flowing add muscle alcohol to absolve amylaceum repressible craft in ferment course and a new bacterial strain, which comprises the following steps: culturing fungus with generating natural abscisic acid in the first grade liquid culture medium; seeding the cultured first grade on the second liquid culture medium to culture; flowed-adding supplement material into the third grade liquid culture medium and muscle alcohol at the same time; proceeding yeast; collecting abscisic acid from the ferment culturing liquid.

A water-soluble florfenicol with high solubility (10000 PPM) and low cost is prepared from florfenicol powder and glucose powder through proportional mixing and stirring.

The invention discloses a method for producing glucaric acid by constructing recombinant saccharomyces cerevisiae and fermenting and belongs to the technical field of bioengineering. The method comprises the following steps: knocking out an OPI gene of saccharomyces cerevisiae BY4741; introducing myo inositol-1-phosphate synthase and inositol monophosphatase from the saccharomyces cerevisiae, inositol from arabidopsis thaliana and uronic acid dehydrogenase from pseudomonas syringae into the saccharomyces cerevisiae through constitutive plasmid pY26-GPD-TEF, and realizing approach construction of the saccharomyces cerevisiae from glucose to the glucaric acid. According to the method disclosed by the invention, by use of a constructed metabolic pathway, non-selectivity, high energy consumption property and high cost performance of a chemical oxidation method are avoided; the low-priced glucose is directly transformed into D-glucaric acid with high added value by fermentation culture of engineering bacteria; the method has the advantages of mild reaction conditions, high transformation rate and fewer byproducts; production cost can be greatly reduced.

Substance productivity is improved by introducing a metabolic pathway for synthesis of acetyl-CoA or acetic acid from glucose-6-phosphate into yeast. Acetic acid productivity, acetyl-CoA productivity, and productivity of a substance made from acetyl-CoA-derived are improved by attenuating genes involved in the glycolytic system of yeast and introducing a phosphoketolase gene into the yeast.

The invention relates to a dual-hydrophilic thermo-sensitive polymer / lactic acid polymer composite nanofiber felt and a preparation method thereof. The nanofiber felt comprises the following components: dual-hydrophilic thermo-sensitive polymer and lactic acid polymer with the mass ratio of 10:1. The preparation method comprises the following steps: (1) carrying out free radical polymerization reaction on glucaric acid divinyl ester and N-isopropyl acrylamide to obtain the dual-hydrophilic thermo-sensitive polymer; (2) dissolving the high polymer in a solvent, stirring for 1-4 hours, and carrying out ultrasonic degassing to obtain a spinning solution A; (3) dissolving the lactic acid polymer in the solvent, stirring for 1-8 hours, carrying out ultrasonic degassing to obtain a spinning solution B; and (4) mixing the spinning solution A with the spinning solution B, and carrying out electrostatic spinning to obtain the dual-hydrophilic thermo-sensitive polymer / lactic acid polymer composite nanofiber felt. According to the invention, the method is continuously feasible, the operation is simple and easy, industrialization is easy to realize, and the obtained nanofiber felt can be used for carrying medicines and control the release of the medicine; and the nanofiber felt can also be implanted into a release system and can be used in the fields of tissue engineering scaffold and the like.

The invention provides a method for production of ethanol by continuous fermentation of immobilized yeast cells, and the method comprises the following steps: (1) a fiber material is attached to a support frame, and is filled into a bioreactor; (2) yeast cells are immobilized in the fiber material in the bioreactor; (3) a fermentation medium is added into the bioreactor to begin ethanol fermentation; (4) when glucose in the fermentation medium is consumed, a fermentation liquid flows out of the bioreactor, the ethanol is collected, the fermentation medium is added, and then the step (4) is repeated. The method uses the fiber material for immobilization of the yeast cells for continuous fermentation to produce the ethanol, the fiber material as an immobilization material is stably in property, non-toxic, and good in adsorption and mass transfer effects, can be repeatedly used, is easy to achieve continuous production of the ethanol, and in a continuous fermentation process can greatly improve the ethanol yield.