368 results about "Insulin injection" patented technology

A method for controlling an insulin pump using the Bluetooth protocol. The method comprises allocating IDs to insulin pumps and blood sugar level measuring devices, respectively; checking, in a corresponding insulin pump, whether or not blood sugar level data is inputted from a blood sugar level measuring device having a corresponding ID; cumulating inputted data and judging whether or not abnormality occurs; generating a command to allow the insulin pump to operate as it is, when abnormality did not occur; generating a command to change an insulin injection amount of the insulin pump when abnormality occurred, and then, returning to the third step; and determining a system to be out of order when data is not inputted in the checking step, and generating an alarm so that a qualified person can visit a corresponding patient to have a trouble to be directly addressed.

A disposable double pointed injection needle has a needle hub to which a thin needle cannula is permanently fastened and which needle hub can be mounted on to a syringe comprising a dose setting and injection mechanism and a cartridge containing a liquid medicine to be injected subcutaneously into a human body. The needle hub is provided with a safety shield guided on the outside surface of the needle hub. The safety shield is urged in a direction away from the needle hub by a spring located between the needle hub and the safety shield. The safety shield has a number of protrusions guided in guiding tracks on the outside surface of the needle hub. The guiding tracks are designed such that the safety shield during injection is moved towards the needle hub, and after injection is moved away from the needle hub by the spring and locked in an irreversible position where the safety shield covers the needle cannula and prevents accidental needle stick injuries.

A system and method for providing optimal insulin injections to a subject, using a controller, a continuous glucose monitor, and an insulin delivery unit is disclosed. The controller possesses a discrete-time, linear model predictive control law, means for sending information to the insulin delivery unit, and means for receiving information from the CGM. The control law implemented is derived from a discrete-time model of glucose insulin dynamics and an aggressiveness parameter. The result is that using only glucose measurements obtained from sensor readings and, prior values of external insulin infusion and meal and exercise announcement the optimal insulin injection necessary to safely regulate blood glucose can be calculated.

A portable insulin injection pen and blood glucose monitoring device is integrated into a single unit for testing and treating diabetes symptoms. The device has a housing of a size suitable for transport in a user's clothing pocket or handbag. Within the housing is a blood glucose monitoring system for receiving a sample of the user's blood and detecting its glucose level, an insulin injection mechanism for administering an insulin injection, and a microprocessor that calculates an insulin dosage appropriate to the detected blood glucose level and sets the insulin injection mechanism to administer the calculated insulin dosage. A communication device automatically informs a remote emergency service provider, such as 911 or an emergency service to which the user has subscribed, if the microprocessor determines that the detected blood glucose level presents a potential danger to the user. The microprocessor also calculates treatment regimens specific to a particular user based on the detected blood glucose level and displays the treatment regimens on an LCD display. In a particularly advantageous embodiment, a GPS receiver within the housing detects the location of the device, and the communication device, which can be a cellular telephone separate from the housing connected wirelessly to the unit via a Bluetooth connection or cellular telephone circuitry within the housing itself, transmits information regarding the location to the remote emergency service.

An electronic insulin delivery device receives glucose data from a glucose monitor and sets a bolus dose amount. The device may take the form of an insulin pen with automatic priming and accurate dosing provided by a motor in connection with an encoder. The device may communicate with and be controlled by a smart phone device. The smart phone device provides a user interface to receive user data including patient weight, insulin to carbohydrate ratio and exercise factor, and to send instructions to the device, including dose amount. The dose amount is determined taking into account glucose level and trend, and other factors. The delivery device may be in continuous communication with the glucose monitor and smart phone to provide for near real-time adjustments in glucose treatment. Glucose data, insulin injection data, and other relevant data may be stored and accessible to interested parties.

A portable insulin injection pen and blood glucose monitoring device is integrated into a single unit for testing and treating diabetes symptoms. The device has a housing of a size suitable for transport in a user's clothing pocket or handbag. Within the housing is a blood glucose monitoring system for receiving a sample of the user's blood and detecting its glucose level, an insulin injection mechanism for administering an insulin injection, and a microprocessor that calculates an insulin dosage appropriate to the detected blood glucose level and sets the insulin injection mechanism to administer the calculated insulin dosage. A communication device automatically informs a remote emergency service provider, such as 911 or an emergency service to which the user has subscribed, if the microprocessor determines that the detected blood glucose level presents a potential danger to the user. The microprocessor also calculates treatment regimens specific to a particular user based on the detected blood glucose level and displays the treatment regimens on an LCD display. In a particularly advantageous embodiment, a GPS receiver within the housing detects the location of the device, and the communication device, which can be a cellular telephone separate from the housing connected wirelessly to the unit via a Bluetooth connection or cellular telephone circuitry within the housing itself, transmits information regarding the location to the remote emergency service.

The non-invasion blood sugar instrument for closed-loop insulin injection has built-in radio communication module, electrochemical electrode to extract hypoderis tissue fluid for non-invasion blood sugar detection, and insulin pump coupled through RF communication for insulin injection. The blood sugar instrument extracts hypoderis tissue fluid through the skin continuously and non-invasively with its constant sampling circuit combined with the electrochemical biosensor to, detects the glucose concentration in the tissue fluid and the blood sugar concentration by means of electrochemical process, transmits the blood sugar information and the time information through the RF communication module to the insulin pump for insulin injection and the closed-loop control of blood sugar level. The present invention can alleviate the pain of diabetics and raise his life quality greatly.

The invention relates to a disposable insulin injection pen with adjustable dosage and convenient use and carrying, which comprises a pen cap, a needle head, an injection pipe internally provided with a piston and filled with drugs in advance, an injection sleeve, a positioning block, a screw, a nut pipe, a fixing pipe, a coil pipe, a clutch pipe, a scale positioning device and a button, wherein 0-60 scales which can be observed by a window of the fixing pipe are marked on the coil pipe, a clutch is formed by a face tooth of the clutch pipe and a tooth socket of the coil pipe so as to ensure the dosage is repeatedly adjusted to the accurate position before use, the clutch is switched on by pressing the button, the coil pipe drives the clutch pipe and the nut pipe to rotate by the interaction of a spiral bar of the fixing pipe and a spiral groove of the coil pipe, and thereby ensuring that the screw is pushed forwards to extrude the drugs in the injection pipe out. The screw can not be pushed backwards after use, which avoids repeated use. The invention integrates insulin with the injection pen, and can be discarded after use because a patient can not replace the injection pipe.

The invention discloses a disposable adjustable injection device for insulin injection. The device comprises a protection cover, a disposable syringe needle, an injection refill sleeve, a main deviceshell, an injection refill and an adjusting assembly, a second boss is arranged at one end of the main device shell, and the injection refill sleeve is installed on the outer portion of the second boss; a threaded groove is formed in one end of the injection refill sleeve, an outer thread of the second boss is in mutual threaded connection with the threaded groove, and a first boss is arranged atthe other end of the injection refill sleeve; the outer portion of the first boss is in threaded connection with the disposable syringe needle, a steel needle is inserted in the disposable syringe needle, and the injection refill is installed in the injection refill sleeve; the protection cover sleeves the outer portion of the injection refill sleeve, the adjusting assembly is arranged at the other end of the main device body shell, a fixed sleeve is installed in the main device body shell, and one end of the fixed sleeve protrudes outward to form a flange part. The device has the advantages that the operation is simple, the waste is avoided, and the safety performance is good.

The invention provides an insulin injection service system which is more convenient to use, more reliable and capable of conducting illness state tracking and treatment management according to the actual conditions of patients and the expert knowledge of doctors. The insulin injection service system comprises diabetes diagnosing and treating equipment, a cloud server side and a client side, wherein the cloud server side is connected with the diabetes diagnosing and treating equipment and the client side through a communication network, and the diabetes diagnosing and treating equipment is in data connection with the client side. By means of the insulin injection service system, the expert knowledge of the doctors and the detail data of all the patients can be combined, and individualized treating schemes can be made. In addition, in the treating process of the patients, data can be recorded and tracked, the subsequent treating schemes can be conveniently adjusted in time, and more scientific treating plans can be made for the patients. The insulin injection service system can automatically drive an injection device to conduct injection or automatically prompt the patients to be injected, the work of the doctors is greatly reduced, and it can be ensured that the patients are injected with insulin on time every day.

An injectable formulation containing a rapid acting insulin and a long acting insulin has been developed. The pH of the rapid acting insulin is adjusted so that the long acting insulin, remains soluble when they are mixed together. Preferably, the formulation is administered before breakfast, provides adequate bolus insulin levels to cover the meal and basal insulin for up to 24 hours, and does not produce hypoglycemia after the meal. Lunch and dinner can be covered by two bolus injections of a fast, rapid, or very rapid acting insulin. Alternatively, by adjusting the ratio of rapid to long acting insulin, the long acting insulin may be shortened to a 12 hour formulation, and re-administered to the patient at dinner time, providing a safe and effective basal insulin level until morning. As a result, a patient using intensive insulin therapy should only inject three times a day.

The invention relates to an intelligent insulin pump system comprising an open-ring type insulin pump which is provided with an electric control unit, the electric control unit of the insulin pump is bidirectionally connected with an upper computer through a wireless module or a USB interface, insulin injecting management software is arranged in the upper computer which receives equipment information, setting information and insulin injection historical information from the insulin pump, and an insulin secretion curve model is generated by the insulin injecting management software and then is inputted to the electric control unit of the insulin pump to control the operation of the insulin pump. Because the insulin secretion curve model is automatically generated or manually established in the insulin injecting management software on the upper computer and is transmitted to the insulin pump by utilizing modules comprising Zigbee and the like in a wireless form or utilizing the USB interface in a wired form, the intelligent insulin pump system dispenses with the trouble of setting a large number of insulin outputting parameters in only several keys and LCD (Liquid Crystal Display) layering menus, thereby being convenient for the operation of users.

The invention discloses a novel insulin pump, which comprises a blood sugar detection system, a control system and an insulin injection system, wherein the blood sugar detection system comprises a blood sugar sensor and a wireless transmitting module which is connected with the blood sugar sensor; the blood sugar detection system can be used for continuously detecting the blood sugar content of a diabetic patient, and can be used for transmitting the blood sugar content to the control system in a wireless way; the control system comprises a wireless receiving module for receiving blood sugar data transmitted by using the blood sugar detection system, and a microcontroller system; the wireless receiving module is used for transmitting the received blood sugar data to the microcontroller module; and the dosage of insulin required be injected is obtained by calculating with a micro-controller and correcting with a model. In the novel insulin pump, a closed-loop insulin injection way is adopted innovatively, the working principle of secretion of insulin from the pancreas of a normal human body is simulated, and the blood sugar data of the patient is measured by using the blood sugar detection system. According to the novel insulin pump, the injection dosage of insulin can be adjusted in real time according to the blood sugar content of the patient, so that the aim of accurately injecting insulin is fulfilled.

The invention relates to an insulin injection pen which comprises a pen cap, a needle, an injection pipe, an injection sleeve pipe, a locating fixture block, a screw, a nut pipe, a fixing pipe, a rotating pipe and a button, wherein a piston is arranged in the injection pipe, and insulin is filled in the injection pipe in advance. Partial threads on two sides of the screw are respectively cut off along the axial direction so that two sections which are parallel to each other are formed. A pressing head is arranged at the front end of the screw, and the screw is coupled with inner threads of the nut pipe. The injection pen further comprises a rotating handle and a rotary spring. The rotating handle is arranged at the outer end, namely, the side opposite to the pen cap, of the injection pen, the outer end of the rotating pipe is arranged in the rotating handle and is fixed on the rotating handle, the other end of the rotating pipe is connected with the nut pipe in a clamping mode, the locating fixture block is sleeved outside the rotating pipe and is connected with the rotating pipe in the clamping mode; the nut pipe is arranged between the pressing head and the locating fixture block; and the rotary spring is sleeved on the rotating pipe, one end of the rotary spring is fixed on the inner side of the rotating handle, and the other end of the rotary spring is fixed on the locating fixture block. According to the insulin injection pen, repeated usage can be achieved through repeated adjustment of the locating fixture block, the rotary spring and a clutch spring.

The invention relates to a blood glucose detection method based on a glucose meter. The method comprises the following steps: 1) the glucose meter is provided, a control terminal comprises automatic insulin injection equipment, electrocardiogram detection equipment, blood glucose detection equipment and an AVR32 chip, wherein the electrocardiogram detection equipment and the blood glucose detection equipment are used for extracting electrocardiogram data and blood glucose data of a detected person respectively; the AVR32 chip is connected with the automatic insulin injection equipment, the electrocardiogram detection equipment and the blood glucose detection equipment respectively, determines whether to send electrocardiogram parameter alarm signals or not on the basis of the electrocardiogram data and determines a control strategy of the automatic insulin injection equipment on the basis of the blood glucose data; 2), the glucose meter is used. With adoption of the method, an automatic insulin injection mode is adopted to replace the original manual insulin injection mode while whether the electrocardiogram data of the detected person are abnormal or not can be detected automatically, and the medical effect on the detected person is improved.

An apparatus and method for automatically supplying insulin based on exercise amount are provided. The apparatus includes a blood sugar measurer for measuring a blood sugar level of a patient; a controller for, comparing the measured blood sugar level with a predetermined blood sugar level, if the measured blood sugar level is greater than or equal to the predetermined blood sugar level, determining whether a current time is within a blood sugar change time zone, if the measured blood sugar level is equal to or higher than the predetermined blood sugar level, and if the current time does is not within the blood sugar change time zone, acquiring exercise amount information about the patient and determining a dose of insulin to be injected inject into the patient based on the acquired exercise amount information, if the current time does not fall within the blood sugar change time zone; and an insulin injector for injecting the determined dose of insulin into the patient.

The invention discloses a disposable array miniature injection needle head which comprises a lower needle base and an upper needle base, wherein the lower needle base is a columnar cylinder of which one end is provided with an opening and the other end is provided with a top cover and which is connected with an injecta reservoir; the upper needle base is arranged above the top cover of the lower needle base, and a cavity is formed between the upper needle base and the top cover; a through hole for communicating the columnar cylinder and the cavity is formed on the top cover, and an injecta extracting needle is arranged in the through hole; one end of the injecta extracting needle is communicated with the cavity, the other end of the injecta extracting needle is positioned in the columnar cylinder, and injecta is extracted from the reservoir to the cavity; at least two needle tubes are arranged on the upper needle base; and one end of each needle tube is a needle tip for puncturing andinjecting the injecta, and the other end of each needle tube is arranged on the upper needle base and is communicated with the cavity. The needle head can be used for the conventional insulin injection pen directly, and medicines such as the insulin and the like can be injected beneath the skin of multiple parts of human bodies vertically, quickly, painlessly, safety and conveniently without leakage under the condition that skin is not pinched by using a plurality of thin and short needle tubes, so the hidden danger of injecting the medicines into muscles is avoided, and the using compliance of patients is improved.

The invention relates to an insulin syringe needle with a needle tip protection function. The insulin syringe needle comprises a needle body, a needle seat, a main shell and an outer jacket, and is characterized in that a trigger pipe, a front casing pipe and a spring are arranged in the main shell, the trigger pipe is used for protecting an injection section of the needle body before the application, and the front casing pipe is used for protecting the injection section of the needle body after the application. Before the application, the trigger pipe stretches out of the main shell and stays at a needle body protection stage, and the front casing pipe is arranged in the main shell; after the application, the trigger pipe is arranged in the main shell, the front casing pipe stretches out of the main shell and stays at a needle body protection state. The unlocking of the trigger pipe and the front casing pipe is correlated to the state whether the syringe needle is prepared for injection or not, and the unlocking of the trigger pipe and the front casing pipe is triggered by utilizing a tail cover and the needle seat when in installation, and safety and convenience in use can be improved.

The invention relates to a disposable safe insulin injection needle head matched with an insulin pen to be used. The disposable safe insulin injection needle head comprises a needle body, a needle seat, a main casing and an outer sheath, wherein the outer sheath is arranged outside the main casing in a sleeving way. The disposable safe insulin injection needle head is characterized in that a locking structure achieving a matching effect through a clamp block and a clamp opening is arranged between the outer sheath and the main casing, a seat disc is arranged on the needle disc, the outer edge of the seat disc has the sliding positioning connecting relationship with the inner edge of the main casing, and during the injection needle head installation, the axial thrust of the insulin pen is used, so that the seat disc moves to a second positioning position from the first positioning position, the outer edge of the seat disc jacks up the clamp block arranged on the outer sheath, the clamp block is unbuckled from the clamp opening, the outer sheath is unlocked with the main casing, and in the state, the outer sheath is allowed to be picked away. The disposable safe insulin injection needle head has the advantages that whether the outer sheath is allowed to be picked away or not and whether the insulin pen and the injection needle head are prepared for the injection state or not are associated, the use safety and the use convenience of the injection needle head are greatly improved.

A wearable liquid supplying device for insulin injection is fixed on a user's body through a ring belt and includes a carrier body, a flow-guiding-and-actuating unit, a sensor, an air bag, a miniature air pump and a driving chip. The sensor measures sweat on human skin to detect a level of the blood glucose. The driving chip receives the glucose monitoring data and accordingly controls the actuation of the flow-guiding-and-actuating unit and the open / closed states of the switching valves. The miniature air pump is enabled to inhale gas into the air bag, so that the air bag is inflated and the ring belt contacts the human skin tightly. The flow-guiding-and-actuating unit is enabled to generate a pressure difference so that the insulin liquid is transported to a liquid guiding outlet through a liquid guiding channel and flows into the microneedle patch for being injected into the subcutaneous tissue.

The insulin pump of the present invention relates to a portable electronic controlling insulin injection device, which can inject the insulin to the human body under a certain time and certain quantity. The present invention is helpful for keeping stable blood sugar for the diabetes patients. The present invention can be widely used in the 1 type diabetic patients, 2 type diabetic patients and the diabetic patients with pregnancy. The structure comprises the insulin pump body, the transparent medicine store cabin, the medicine store device, the medicine injection piston, the medicine injection pushing rod, the battery cabin, the battery, the digital display, the motor, the reducer, the motor seat and a joint of the medicine transportation. A medicine store cabin is arranged in one side of the insulin pump body. A transparent observation window is arranged outside the medicine store cabin. The medicine store tool is inserted in the medicine store cabin. A motor cabin is arranged in the back part of the medicine store cabin. The motor is arranged in the motor cabin. The reducer is connected with the motor directly. The output shaft of the reducer is provided with the thread. The hollow medicine injecting rod is provided with an inner thread. The one end of the injection rod is provided with the outer thread. The medicine injection rod sleeve is arranged outside the motor and the reducer.

A wearable liquid supplying device for human insulin injection is fixed on a body of human through a ring belt and includes a substrate, a flow-guiding-and-actuating unit, a sensor and a driving chip. The substrate has a liquid storage chamber. The flow-guiding-and-actuating unit has a liquid guiding channel in communication with a liquid storage outlet of the liquid storage chamber and a liquid guiding outlet. The sensor measures a blood glucose level and generates measured data correspondingly. The driving chip receives the measured data from the sensor and controls the actuation of the flow-guiding-and-actuating unit and the open / closed states of the switching valves. The flow-guiding-and-actuating unit is enabled to generate a pressure difference so that the insulin liquid is transported to the liquid guiding outlet through the liquid guiding channel and flows into the microneedle patch for allowing the microneedles to inject the insulin liquid into the subcutaneous tissue.

A disposable double pointed injection needle has a needle hub to which a thin needle cannula is permanently fastened and which needle hub can be mounted on to a syringe comprising a dose setting and injection mechanism and a cartridge containing a liquid medicine to be injected subcutaneously into a human body. The needle hub is provided with a safety shield guided on the outside surface of the needle hub. The safety shield is urged in a direction away from the needle hub by a spring located between the needle hub and the safety shield. The safety shield has a number of protrusions guided in guiding tracks on the outside surface of the needle hub. The guiding tracks are designed such that the safety shield during injection is moved towards the needle hub, and after injection is moved away from the needle hub by the spring and locked in an irreversible position where the safety shield covers the needle cannula and prevents accidental needle stick injuries.

The invention relates to the field of medical appliances, and discloses an intelligent automatic insulin injection pen. The injection pen comprises a pen cap (1), a piston (2) arranged in the pen cap (1) and a control system, wherein the piston (2) is connected with a drive rod (3); the control system comprises a singlechip (5) and a servo motor (4); the singlechip (5) is used for controlling operation of the servo motor (4); the servo motor (4) is connected with the piston (2) by virtue of the drive rod (3), and is used for controlling movement of the piston (2). The intelligent automatic insulin injection pen has the advantages of accurately controlling the insulin injection dosage, reminding users of taking medicines, reminding users the rest dosage of insulin, controlling the insulin storage temperature and prompting users to carry the insulin injection pen for outdoors.

Equivalent insulin pump retrospective virtual basal rates for daily injections are constructed from planned insulin injections according to a virtual basal rate profile developed for a patient, and a database of historical insulin injections, i.e. basal injections actually administered by the patient, providing a unified framework for analysis, design, optimization, and adaptation of MDI (multiple daily injections) and CSII (continuous subcutaneous insulin infusion (i.e. insulin pump)) treatment parameters for patients with diabetes.

A sheet for guiding location of insulin injection has a sheet shape. The sheet has a first face and a second face opposite to the first face. A reference mark is formed at a first portion of the sheet to correspond to user's navel. A plurality of injection holes is formed at a second portion of the sheet opposite to the first portion to inject insulin, so that the insulin is injected at a left portion with respect to the reference mark by using the first face and the insulin is injected at a right portion with respect to the reference mark. A manual of the sheet is indicated on the first face and / or the second face. A day of a week is indicated corresponding to and adjacent to each of the injection holes. Thus, patient's convenience may be enhanced.

The invention discloses an insulin pump with a dynamic closed-loop control in the field of medical equipment. The insulin pump comprises an administration mechanism, a driving mechanism, a detection mechanism and a dynamic control module, wherein the administration mechanism is connected with the insulin pump and transmits insulin injection amount information; the driving mechanism is connected with an injection unit of the insulin pump, and transmits and controls the injection amount information; the detection mechanism is connected with a glucometer and transmits human body blood glucose information; and the dynamic control module is connected with the driving mechanism of the insulin pump and transmits insulin-blood glucose level control information. The insulin pump with the dynamic closed-loop control can effectively reduce the unstabilizing factors due to a complex blood glucose system and has the relatively nice robustness after simulation testing. The insulin pump can control the blood glucose level of the diabetics and the injection amount of the insulin in time through model prediction and iterative control, so that the blood glucose level of the diabetics tends to be stable; and therefore, the effect of the insulin pump to control the injection automatically is achieved.

The invention provides a disposable safe insulin injection needle head, which comprises a needle body, a needle seat, a main casing, an outer sheath and a triggering tube and is characterized in that the needle seat is formed by fixedly connecting a seat disc and a seat rod, the outer edge of the seat disc and the inner edge of the main casing have the sliding positioning connection relationship, i.e., during the injection needle head installation, the axial thrust of the head part of the insulin pin is used, so that the seat disc moves to a second positioning position from a first positioning position, the back part of the triggering tube is arranged on the seat rod in a sleeving way, the front end of the triggering tube is jacked and leaned on the inner end surface of the front part of the outer sheath, a third positioning structure is arranged between the triggering tube and the seat rod, and when the triggering tube is positioned in a third positioning position relative to the seat rod, the seat disc is positioned in the first positioning relative to the main casing; when the seat disc moves to the second positioning position from the first positioning position in the main casing, the triggering tube and the seat rod relieve the third positioning and form slide connection. The disposable safe insulin injection needle head has the advantages that whether the triggering tube is unlocked or not after being positioned or whether the injection needle head is prepared for the injection state or not are associated, and the use safety and the use convenience are improved.

The invention discloses an automatic insulin injection system which comprises an insulin storage sac, an insulin pump, an injection needle, a controller, a blood glucose concentration sensor, an alarm, a display A and a display B, wherein the insulin storage sac is connected with the insulin pump; the injection needle is connected with the insulin pump; and the controller is connected with the blood glucose concentration sensor, the alarm, the display A and the display B respectively. The automatic insulin injection system disclosed by the invention can detect the change of the blood glucose concentration of the diabetic anytime; and once the blood glucose concentration in the body of the diabetic changes, the controller can immediately calculate the insulin concentration lacking in the body and perform injection for the human body, and can quickly recover the blood glucose concentration of the diabetic to normal so as to reduce the complications caused high blood glucose concentration.