221 results about "Malathion" patented technology

Decontamination formulations for neutralization of toxic industrial chemicals, and methods of making and using same. The formulations are effective for neutralizing malathion, hydrogen cyanide, sodium cyanide, butyl isocyanate, carbon disulfide, phosgene gas, capsaicin in commercial pepper spray, chlorine gas, anhydrous ammonia gas; and may be effective at neutralizing hydrogen sulfide, sulfur dioxide, formaldehyde, ethylene oxide, methyl bromide, boron trichloride, fluorine, tetraethyl pyrophosphate, phosphorous trichloride, arsine, and tungsten hexafluoride.

The invention discloses a pesticide composition containing dinotefuran. Applied as a water dispersible granule, a suspending agent or a wettable powder, the composition comprises 1%-80% of an active component, 1%-20% of a composite auxiliary agent and the balance of a filling material. Applied as an emulsion in water or a micron emulsion, the composition comprises 1%-40% of the active component, 1%-20% of the composite auxiliary agent, 1%-40% of a solvent, and the balance of water. The active component comprises dinotefuran and an other pesticides in a mass ratio of 1:(0.2-50), wherein the other pesticides is malathion, DDVP, phoxim or fipronil. The pesticide of the present invention has a good insecticidal effect, a long insect control time, a wide insecticidal scope, low costs, does not cause resistance in insects, and is safe for crops and environment-friendly.

The invention relates to a multifunctional seedling special fertilizer and a preparation method thereof, and belongs to the technology field of fertilizer. The multifunctional seedling special fertilizer comprises the following components: A components comprising plant ashes, rooting powders and malathion, B components comprising nitrogenous fertilizer, phosphate fertilizer and potash fertilizer, and C components comprising acidity regulator. The fertilizer is prepared by the following method: the material in the B components is crushed, appropriate acidity regulator is added in the plant ashes, the rooting powders and the malathion are added after the pH value of the plant ashes is adjusted to 6 to 8 to form the A components; the A components and the B components are evenly mixed, and pelleting adhesive is added for pelleting and drying. The multifunctional seedling special fertilizer has obvious improving effect to soil, increases the content of organic matters in the soil, and effectively keeps soil from packing together; the organic matters in the soil can be increased by 15 percent to 30 percent after using the fertilizer for 3 to 4 years. The soil microbiota is improved obviously.

The invention relates to a method for detecting ten types of organophosphorus pesticides by using magnetic separation-gas chromatography. The method is used for quickly detecting ten types of organophosphorus pesticides (dipterex, methamidophos, acephate, omethoate, moncrotophos, dimethoate, phosphamidon, parathion-methyl, malathion and chlorpyrifos) based on combination of solid-phase extraction, magnetic separation and the gas chromatography. The method comprises the following steps: preparing a magnetic solid-phase extraction agent, establishing a combination system of the magnetic separation and the gas chromatography, and detecting the organophosphorus pesticides in objects to be detected. A method capable of quickly separating and detecting ten types of organophosphorus pesticides at high sensitivity simultaneously is established by taking prepared magnetic chitosan microspheres with high absorption performance on the ten types of organophosphorus pesticides such as dipterex and the like as adsorption functional materials and using combination of the solid-phase extraction, magnetic separation and the gas chromatography. The method is simple in experimental operation, high in detection sensitivity, low in cost and applicable to detection of residues of ten types of organophosphorus pesticides such as trace dipterex and the like in all products.

The invention discloses a special fertilizer for seedling culture. The invention is characterized in that the fertilizer is composed of the following components in parts by weight: 10-20 parts of ammonium sulfate, 8-15 parts of monoammonium phosphate, 15-20 parts of calcium superphosphate, 10-18 parts of potassium sulfate, 4-9 parts of sulfur, 2-4 parts of ferrous sulfate, 0.02-0.04 part of malathion, 10-15 parts of livestock / poultry manure, 10-12 parts of rape seed cake, 0.8-1.5 parts of ferment, 15-25 parts of plant ash, 0.8-1.5 parts of ferment, 10-12 parts of Chinese herbal medicine residue, 15-25 parts of vinasse, 20-30 parts of weed, 5-10 parts of cottonseed meal, 15-20 parts of rice bran and 20-25 parts of medical stone. The special fertilizer for seedling culture can enhance the stocking percent, reduce the disease and pest damage and improve the soil. The special fertilizer for seedlings ensures the timely and sufficient supply of nutrients, and shortens the seedling recovery time. The plant ash and other raw materials in the special fertilizer enhance the inhibiting action on soil insects and harmful bacteria in soil, and reduce the disease and pest damage, thereby enhancing the soil organic matter content and effectively controlling soil hardening.

The invention discloses a preparation method and application of an electrochemical malathion biosensor based on a bi-metal in-situ composite two-dimensional nanomaterial and belongs to the technical field of novel nano functional materials and biosensors. A novel flaky magnetic nano light-sensitive material FeMn-N@TiO2 is prepared for the first time; through good bio-compatibility, large specific area and ferromagnetism of the material, a malathion antibody is loaded, then horse radish peroxidase is fixed through the interlinking effect of glutaraldehyde, in the detection process, due to the fact that horse radish peroxidase can catalyze hydrogen peroxide, electrochemical signals are generated, through the influences of specific quantitative combination of the antibody and an antigen on electron transmission capacity, the current intensity is correspondingly reduced, and finally the electrochemical biosensor which is low in cost, high in sensitivity, good in specificity, rapid in detection and easy to prepare and detects malathion is prepared.

The invention discloses a method for growing rice by using an enzyme. The method is characterized in that the method comprises a seedbed management process; the seedbed management process comprises the steps of bed soil preparation, soil disinfection and seedbed fertilization; the bed soil preparation step is realized by blending dry field soil or paddy field soil with an enzyme fertilizer; the soil disinfection step is realized by spraying an environmentally-friendly enzyme solution on soil based on the conventional soil disinfection; and the seedbed fertilization step is realized by additional application of the enzyme fertilizer based on the conventional seedbed fertilization. The invention also discloses an enzyme rice. The chalky grain percentage is lower than 8.5, the amylose contentpercentage is lower than 17.25, the lead content is less than 0.02 mg / kg, the inorganic arsenic content is less than 0.01 mg / kg, the cadmium content is less than 0.01 mg / kg, and the content of malathion, fenitrothion and pretilachlor is 0; and the method solves the problems of soil damages and environment and rice pollution caused by high dosages of chemical fertilizers and pesticides, in existing conventional rice growing methods.

The invention relates to engineering organophosphorus hydrolase, nucleic acid, a mutant and an application of the engineering organophosphorus hydrolase and the mutant and belongs to the technical field of bioengineering. The engineering organophosphorus hydrolase is an organophosphorus hydrolase mutant constituted by new amino acid sequences formed after amino acid substitution of one or more of amino acid residues on the 55th site, the 57th site, the 83th site, the 114th site, the 137th site, the 188th site or the 262th site of an amino acid sequence shown as SEQ ID No.1, and the activity of the engineering organophosphorus hydrolase is improved. Compared with the prior art, the organophosphorus hydrolase mutant has the advantages that the malathion catalytic activity is improved by 36.7 times, the mutant keeps excellent thermal stability of a female parent, and the half-life period at 50 DEG C reaches 65 h. The organophosphorus hydrolase mutant can efficiently degrade common organophosphorus pesticides such as malathion and the like, has excellent thermal stability and has very good application prospect in the field of degradation of the organophosphorus pesticides.

The invention relates to the technical field of pesticide residue analysis and determination, in particular to an electrochemiluminescence sensor constructed based on hollow copper-cobalt-MOF and usedfor simultaneously detecting two pesticides and a method for measuring acetamiprid and malathion by using the electrochemiluminescence sensor. The method comprises the steps of preparing the electrochemiluminescence sensor, operating the sensor to simultaneously measure acetamiprid and malathion and the like. According to the sensor for simultaneously detecting the two pesticides, hollow copper-cobalt-MOF enhanced luminol and g-C3N4 compounded by gold nanoparticles are used as an electrochemical luminescence substance, so that the two pesticides including acetamiprid and malathion are simultaneously detected. The electrochemiluminescence sensor for simultaneously detecting the two pesticides based on the hollow copper-cobalt-MOF is simple in material synthesis, small in interference of the two luminescent substances, high in sensitivity and good in selectivity.

The invention provides a malathion molecularly imprinted polymer and a synthetic method of a malathion restricted access media-molecularly imprinted polymer. The malathion molecularly imprinted polymer is synthesized by using a molecular imprinting technique and a bulk polymerization method. A prepared molecularly imprinted solid phase extraction column has a recovery rate of 97.8% for malathion. The extraction effect is obviously better than that of commercialized solid phase extraction columns. By using the restricted access media-molecular imprinted technology, the precipitation polymerization and suspension polymerization are optimized to synthesize malathion molecularly imprinted microspheres and restricted access media-molecularly imprinted microspheres. The resulting microspheres are made into a solid phase extraction column. Compared with the commercialized solid phase extraction columns, the solid phase extraction column has the advantages of high recovery rate, low standard deviation, and good reproducibility.

The invention relates to a gas chromatographic method for detecting the residue amount of nine kinds of organophosphorus pesticide in rice. Qualitative and quantitative detection on the pesticide residues of dichlorphos, acephate, omethoate, dimethoate, phorate, malathion, fenitrothion, isocarbophos and triazophos is achieved. The gas chromatographic method is characterized in that acetonitrile is used as extractant, extracting solutions are concentrated through a gas blowing concentrator, and after volume metering is carried out through acetone, trace analysis is directly carried out on a gas chromatograph. The gas chromatographic method has the advantages that the separating effect of a chromatographic column on a target object is good, the detection result is high in accuracy, reproducibility is good, and method sensitivity meets the technical requirement of multi-pesticide-residue detection; compared with the method of GB / T5009.145-2003 national standards (the detection of multiple kinds of residues of organophosphorus and carbamates pesticide in plant food), the gas chromatographic method is simpler, simplifies the pre-processing processes of samples, shortens detection time, and saves cost.

The invention relates to a special fertilizer for nursery stock cultivation. The special fertilizer comprises the following components in parts by weight: 20-30 parts of ammonium sulfate, 8-15 parts of monoammonium phosphate, 15-25 parts of potassium sulfate, 4-10 parts of sulphur, 2-4 parts of ferrous sulfate, 0.02-0.04 part of malathion, 25-35 parts of livestock and poultry manure, 10-12 parts of rapeseed cakes, 0.8-1.5 parts of leavening agent, 20-30 parts of plant ash and 1-5 parts of ABT rooting powder. The efficient biological organic compound fertilizer is prepared by taking the common livestock and poultry manure as the main organic raw material according to the high-temperature composting principle; and the special fertilizer has the characteristics of simple production method, low cost, long fertilizer efficiency, no pollution, high efficiency, comprehensive nutrient elements, balanced nutrients and the like, contains a great number of nutrient elements for nursery stock growth and trace elements for nursery stock growth, is particularly suitable for nursery stock growth, has relatively high social and economic benefits and provides an important technical support for the healthy development of nursery stock industry and the deep development of afforestation work.

The invention discloses a gas chromatography method for detecting the residual quantity of eight organophosphorus pesticides contained in soil (loamy soil, clay and sandy soil) with different textures, and the gas chromatography method realizes the qualitative and quantitive detection of the pesticide residues of acephate, omethoate, dimethoate, phorate, malathion, fenitrothion, isocarbophos and hostathion. The gas chromatography method is characterized in that a dichloromethane-acetone (V:V=1:1) mixed solvent is used as an extracting agent; and an extracting solution is concentrated, metered in volume and filtered and then directly subjected to trace analysis on a gas chromatograph. The gas chromatography method disclosed by the invention has the advantages of good separation effect of chromatographic columns on target objects, high detection result accuracy and good repeatability and meets the detection requirements of residual pesticides on sensitivity; compared with the GB / T14552-2003 (gas chromatography method for detecting the organophosphorus pesticides contained in water and soil) national standard method, the gas chromatography method disclosed by the invention is simpler and more convenient, simplifies the preprocessing steps of a soil sample, shortens the detection time and saves the cost.

The invention discloses a liquid chromatography-tandem mass spectrometry method for measuring 18 semi-volatile organic pollutants in water. According to the method, a clean water sample such as surface water, drinking water, and the like is simply filtered by a 0.22 [mu]m micro-porous filter membrane, and then a liquid chromatography-mass spectrometry instrument is used to separate and detect the following 18 compounds in water: aniline, benzidine, acrylamide, picric acid, carbaryl, deltamethrin, microcystic toxin-LR, dibutyl phthalate, bis(2-ethylhexyl) phthalate, dichlorvos, trichlorphon, parathion, methyl parathion, malathion, dimethoate, demeton, atrazine, and carbofuran. The provided method can detect many target substances. The detection range of the method is 0.001 to 0.49 [mu]g / L, the relative standard deviation is 0.7 to 15.4%; and the analysis method has the advantages of high sensitivity, quick analysis speed, little pollution, and simple and efficient pretreatment, is especially suitable for standard analysis of drinking water source monitoring, and solves the problems of bad conformability, large labor strength, and low analysis efficiency of the conventional standard method.

The invention relates to the application of carboxylesterase D-1CarE3, gene D-1CarE3 and carboxylesterase D-1CarE3 in the degradation of pesticides malathion and carbaryl. The amino acid sequence of carboxylesterase D-1CarE3 is as shown in SEQ ID NO.1, the amino acid sequence of the encoding gene D-1CarE3 of the carboxylesterase is as shown in SEQ ID NO.2, and the carboxylesterase comprises recombinant vector of carboxylesterase D-1CarE3 and the recombination strain of the carboxylesterase D-1CarE3. The invention further provides the application of the carboxylesterase D-1CarE3 in the degradation of pesticides malathion and carbaryl. The carboxylesterase has the advantages that the cultivation period is short, the pure protein is easy to obtain, and the malathion can be degraded at high efficiency, and compared with the reported carboxylesterase from insects, the carboxylesterase is higher in efficiency for depredating the pesticide malathion and carbaryl. The invention has an important significance in the aspect of the treatment of pesticide pollution.

The invention relates to a pesticide combination, comprising a compound which consists of the neonicotine pesticide thiamethoxam and at least one pesticide selected from organophosphorus pesticides of pyridaphethione, malathion and phoxim; the compound can be processed into aqueous emulsion, water dispersible granule and suspension emulsion. The field experiment of the pesticide compound of the invention for treating different objects proves that the killing efficiency is high and the preventing and controlling scope is very wide, therefore, the invention can effectively prevent and control main pests such as rice borer, rice plant hopper, cotton aphid, apple aphid, diamond-back moth, European red mite, orange coccid, pieris rapae, bemisia tabaci and the like.

The invention discloses a fluorescence detection kit based on an aptamer. The fluorescence detection kit comprises exonuclease III, a reaction buffer solution, DNA1, DNA2 and stem-loop structure nucleic acid H1. The aptamer is used for specific recognition of a molecular recognition element, a 3' double-chain nucleic acid structure with a flush end is obtained, and circular signal amplification isperformed after exonuclease III is added, so that a large amount of double-chain DNA become single-chain DNA; after fluorescent dye is added, the content of to-be-detected molecules is detected by distinguishing fluorescence intensity change. The linear range for malathion detection is 10 pM to 100 nM, and the limit of detection is 5 pM; meanwhile, the detection system has good specificity and the detection results cannot be interfered by other common analogues. No separation and purification processes are required in the detection process, the kit can be used for detection after simple mixing, has the advantages of being simple to operate, low in cost, rapid in response and the like and can be used for rapid and high-sensitivity detection of pesticide residues in food, water sources, soil and other samples.

The invention discloses a method for photoelectrochemically detecting an organophosphorus pesticide based on a BiOBr / Bi2S3 semiconductor heterojunction generated by biological induction. The method comprises the following steps: mixing malathion with avidin-modified magnetic beads, biotin-modified auxiliary DNA and a malathion aptamer, incubating, removing part of the malathion aptamer by using malathion to recover the single strand of the auxiliary DNA, triggering by using the auxiliary DNA to form G-rich dsDNA, and embedding the dsDNA into Hemin and MnTMPyP to catalyze a Na2S2O3 and H2O2 mixed solution to generate H2S. H2S reacts with BiOBr modified on an electrode to generate a BiOBr / Bi2S3 compound, so that the photocurrent is greatly increased, the change of the photocurrent and the concentration of a target object are in a linear relationship in a certain range, HCR signal amplification is designed on the basis of specific recognition of malathion and an aptamer thereof, biocatalysis is utilized to induce a BiOBr / Bi2S3 semiconductor heterojunction to amplify a signal, therefore, high-sensitivity and high-selectivity photoelectric method detection of malathion is realized.

The invention relates to a pesticide combination, which is characterized by comprising the active ingredients including pyridalyl (A) and an organophosphorus insecticide (B) which can be chlorpyrifos, phoxim, profenofos, triazophos, diazinon, pyridaphenthione, malathion or acephate. The pesticide combination of the invention has good control effects on the common pests on such field crops as paddy rice, wheat, corns, cotton, hemp, soybean and the like, and especially has better control effect on lepidopterous pests.

The invention relates to a pesticide for plants and belongs to the technical field of pesticide. The common chemical agents have different-degree damages to vegetables and fruits, for example, omethoate cannot be used in 30 days before harvesting and malathion can produce damage to melons and peaches. The invention provides a nontoxic and nuisanceless pesticide for plants. The pesticide for plants is characterized by comprising 4-6 parts by mass of purslane extract, 4-6 parts by mass of pasque flower extract, 3-8 parts by mass of celandine extract and 2-5 parts by mass of chitin.

The invention discloses detoxication engineering bacteria, and a preparation method and application thereof. The invention provides a recombinant plasmid which is obtained by introducing coded genes of detoxication esterase and coded genes of hydrolase into an enzyme cutting site in plasmid pETDuet-1. The engineering bacteria of the invention can be obtained by introducing the recombinant plasmidinto host bacteria. The engineering bacteria comprise the coded genes of the detoxication esterase and the hydrolase and can realize inducible expression of the detoxication esterase and the hydrolase. Crude enzyme solution obtained by fermentation of the engineering bacteria can also be protected. The engineering bacteria and the crude enzyme solution thereof can simultaneously degrade organic acid esters such as malathion, parathion, high-efficiency cypermethrin, acetofenate and the like and organophosphorus pesticides, and can be used for detoxication of organophosphorus poisoned warm-blooded animals. The invention provides a new way for biological pollution treatment of toxic and harmful compounds such as pesticides remained in water sources, soil and the like by using natural resources of eukaryote and prokaryote.

The invention discloses a manufacturing technique of a balanced-nutrition seedling cultivation fertilizer. The fertilizer comprises the following raw materials in parts by weight: 5-20 parts of urea, 5-25 parts of ammonium sulfate, 1-8 parts of ferrous sulfate, 10-25 parts of calcium superphosphate, 1-8 parts of zinc sulfate, 1-15 parts of sulfur, 0.5-5 parts of Dittany Bark, 0.01-0.2 part of malathion, 0.5-5 parts of radix rehmanniae, 5-20 parts of rape seed cake, 0.5-5 parts of moutan bark, 5-35 parts of plant ash, 0.5-5 parts of skunk bugbane, 0.1-5 parts of ferment, 0.5-5 parts of nutshell, 5-35 parts of vinasse, 0.5-5 parts of herba violae, 10-40 parts of weed and 5-30 parts of rice bran. The technique comprises the following steps: grinding the plant ash into a paste, adding vinasse, and grinding to obtain a mixed thick paste; adding the weed and rice bran into the mixed thick paste to obtain a mixture; and fermenting the rape seed cake and ferment to obtain a fermentation product, adding the fermentation product into the mixture, adding the rest raw materials, drying and pulverizing. The technique can enhance the stocking percent, reduce the disease and pest damage and improve the soil, thereby shortening the seedling recovering time and saving the production cost. The nutrient elements are absorbed in a balanced mode in various growth periods of the seedlings.

The invention discloses multifunctional compound fertilizer for cultivating a nursery-grown plant. The multifunctional compound fertilizer is prepared from the following raw materials in parts by weight: 10 to 20 parts of power-plant ash, 15 to 25 parts of livestock excrement, 0.8 to 1.2 parts of pyroxasulfone, 1 to 1.6 parts of fenclorim, 10 to 16 parts of dispersant, 20 to 30 parts of slow release additive, 0.1 to 1 part of malathion, 4 to 8 parts of rapeseed cake, 8 to 14 parts of plant ash, 1 to 2 parts of sulfur powder, 1 to 2 parts of lime powder, 20 to 30 parts of food processing waste, 2 to 4 parts of compound fertilizer and 2 to 3 parts of EM (Effective Microorganism) microbial inoculum. The multifunctional compound fertilizer for cultivating the nursery-grown plant, which is provided by the invention, is made through biological fermentation and the compounding of multiple environment-friendly materials; nutrient elements of the multifunctional compound fertilizer are complete; soil can be effectively ameliorated; the hardening of the soil, which is caused as chemical fertilizer is excessively used is prevented; the vigorous growth of the nursery-grown plant is promoted; in addition, the fertilizer also has deinsectization and weeding functions; further, after the fertilizer is applied once, a nutrient can be slowly released; the utilization rate of the fertilizer is improved; the loss of fertilizer efficiency is decreased; meanwhile, a preparation method provided by the invention is lower in material cost and concise in process; the raw materials are easily obtained; the multifunctional compound fertilizer has higher use value and a favorable application prospect.

The invention discloses Karbofos emulsion in water, which comprises the following components in percentage by weight: 20 percent to 70 percent of karbofos active compound, 0 to 15 percent of organic solvent, 2 percent to 15 percent of emulsifying agent, 0.5 percent to 5 percent of antifreeze, 0 to 3 percent of thickening agent and the rest of water; the organic solvent is toluene, dimethylbenzene, benzene or C10 aromatic hydrocarbon, the thickening agent is aluminium-magnesium silicate, organobentonite, xanthan gum or carboxymethyl cellulose, the antifreeze is glycol, propanetriol, isopropanol or butanol, and a stabilizing agent is antioxidant 264, epoxy chloropropane, epoxidized soybean oil or benzoperoxide, the emulsifying agent is calcium dodecyl benzene sulfonate or K-12, alkyl naphthalene sulfonate, nonyl phenol polyoxyethylene ether, alkylaryl polyoxyethylene ether, polyoxyethylene fatty acid, PO-EO block polyether, polycarboxylate, polyoxyethylene hydrogenated castor oil and styryl phosphate. The emulsifying agent is more likely to be one or several of PO-EO block polyether, alkyl naphthalene sulfonate, nonyl phenyl polyoxyethylene ether, alkylaryl polyoxyetheylene ether, polyoxyethylene fatty acid and styryl phosphate mixed in any proportion. The Karbofos emulsion in water is a high-efficient, safe, economical, convenient and environment-friendly farm chemical.

The invention relates to a pesticide, in particular to a pesticide for killing cotton bollworms. The technical proposal is as follows: the pesticide is mixed by phoxim, karbofos, sumicidin and an emulsifying agent and is characterized in that the weight percentage of the components is 20 to 40 percent of the phoxim, 20 to 40 percent of the karbofos, 10 to 30 percent of the sumicidin and 30 to 50 percent of the emulsifying agent, and the components of the phoxim, the karbofos, the sumicidin and the emulsifying agent are put in a glass vessel to be mixed evenly according to the mixture ratio. The pesticide has the advantages of strong killing ability, high drug effect and low cost.

The invention discloses a high-efficiency insecticidal composition containing tetrachlorantraniliprole. The insecticidal composition comprises the following effective constituents: an active component A and an active component B, wherein the active component A is tetrachlorantraniliprole, the active component B is any one selected from the group consisting of chlopyrifos, profenofos, malathion and DDVP, and a weight ratio of the active component A to the active component B is 1: 80 to 60: 1. The bactericidal composition provided by the invention exerts a synergistic effect on a plurality of insects doing harm to agricultural production, reduces the dosage of pesticides, decreases residual quantity of pesticides on crops, mitigates environmental pollution, is safe to human beings and livestock, has good environmental compatibility and enables insects not to easily generate resistance.

The present invention provides a topical gel pharmaceutical formulation of insecticide suitable for treating an ectoparasite in a mammal, comprising: a) about 0.1-10% by weight of an insecticide; b) at least about 75% by weight of an organic solvent selected from the group consisting of a lower alkyl alcohol, a ketone, a glycol and a mixture thereof, wherein the organic solvent contains at least about 40% by weight of the lower alkyl alcohol; and c) at least one polymer selected from the group consisting of a cellulosic polymer, acrylates, methacrylates, and polyvinyl pyrrolidone. The present topical formulations encompass a non-flammable solvent for malathion effective in killing head lice. The present gel pharmaceutical formulation preferably contains malathion and optionally contains isopropyl myristate. The present invention further provides a process of preparing as well as a method of treating ectoparasites in a mammal using the same.

The present invention provides a topical gel pharmaceutical formulation of insecticide suitable for treating an ectoparasite in a mammal, comprising: a) about 0.1-10% by weight of an insecticide; b) at least about 75% by weight of an organic solvent selected from the group consisting of a lower alkyl alcohol, a ketone, a glycol and a mixture thereof, wherein the organic solvent contains at least about 40% by weight of the lower alkyl alcohol; and c) at least one polymer selected from the group consisting of a cellulosic polymer, acrylates, methacrylates, and polyvinyl pyrrolidone. The present gel pharmaceutical formulation preferably contains malathion and optionally contains isopropyl myristate. The present invention further provides a process of preparing as well as a method of treating ectoparasites in a mammal using the same.