497results about How to "Avoid fuses" patented technology

Height-adjustable devices suitable for insertion between posterior spinal processes that allow the surgeon to post-operatively adjust the height of the implant.

Height-adjustable devices suitable for insertion between posterior spinal processes that allow the surgeon to post-operatively adjust the height of the implant.

Intraocular devices for use in and attached to the natural lens capsule of an eye are provided. The lens capsule may be maintained in a configuration to avoid post-operative changes that are deleterious to vision. Single or dual optic systems are provided, which may be accommodating. Combinations of devices to obtain dual optic systems are disclosed.

A cyclone gasifying combustion burner and its operation is described. An exemplary burner has an inner cylindrical wall with a contour chamber feeding combustion air into the inner cylindrical wall, with an open end and a solid fuel support end where a combustible material forms a fuel bed. The inner cylindrical wall has a series of inclined air jet holes of substantially predetermined diameter and disposed at substantially predetermined locations therein to create a unidirectional cyclone within a combustion zone defined within the inner cylindrical wall. The air jet holes are disposed at a tangential and vertical angle whereby the combustion air is drawn into the inner cylindrical wall and creates a cyclone flow to mix with the combustion gases released from the flaming pyrolysis fuel bed and causes the combustion gases to flow in a cyclone path within a reaction zone to increase the residency, mixing and turbulence time of the combustion gases and simultaneously precipitate suspended particles against an inner surface of the inner cylindrical wall whereby the particles are caused to gravitate to the fuel bed where they are removed in a controlled manner during the operation of the burner.

The present invention provides methods and compositions for treating various diseases through selective killipg of targeted cells using a combinatorial targeting approach. The invention features protoxin fusion proteins containing a cell targeting moiety and, a modifiable activation moiety which is activated by an activation moiety not naturally operably found in, on, or in the vicinity of a target cell. These methods also include the combinatorial use of two or more therapeutic agents, at minimum comprising a protoxin and a protoxin activator, to target and destroy a specific cell population.

The present invention provides a wire structure where reduction in the amount of current that can be made to flow through the wire can be suppressed (a current comprising a large current density can be made to flow), even in the case where the wire is downsized. A wire structure according to the present invention is provided in an insulating film formed on a base. Here, a trench is formed in the surface of the insulating film. In addition, a plurality of carbon nanotubes are included in this trench. That is, the wire structure according to the present invention includes at least a plurality of carbon nanotubes.

The invention relates to a method and a system for abnormal target detection and relay tracking under a large-range monitoring scene. The system comprises a target detection module, a target identification and tracking control module and an active tracking module, wherein the target detection module is used for carrying out Gaussian background modeling by utilizing a sub-sampled image to obtain aforeground image, computing the coordinate of a target in a digital map and then sending coordinate information to the target identification and tracking control module; the target identification andtracking control module is used for finishing the target tracking, the track recording and the abnormal behavior detection of the target, and if abnormal behavior occurs, a proper pan-tilt video camera is selected according to the coordinate information of the target, and an alarm signal is sent to the active tracking module; and the active tracking module is used for receiving the alarm information of the target identification and tracking control module, controlling the pan-tilt video camera to carry out preset position steering according to the content of the alarm information and then carrying out the detection and the tracking of the moving target. The invention solves the integration problem of multiple paths of image target information under the large-range monitoring scene and realizes the accurate and robust relay tracking of the same target.

Described are the crystal structure of the alpha-helical domain of the gp41 component of HIV-1 envelope glycoprotein which represents the core of fusion-active gp41, methods of identifying and designing drugs which inhibit gp41 function and drugs which do so.

A multi-chamber stimulation device and associated method reliably and automatically distinguish fusion from loss of capture during ventricular stimulation. The stimulation device provides immediate and accurate fusion detection when a loss of capture is suspected in the ventricles without delivering back-up stimulation pulses. To achieve this objective, the far-field signal present in the atrial channel is examined for evidence of a far-field R-wave whenever the ventricular channel detects a loss of capture. If a far-field R-wave is present, fusion is confirmed, and a far-field R-wave is absent, loss of capture is confirmed. Additionally, the stimulation device inhibits unnecessary back-up stimulation and threshold tests when fusion occurs, and provides appropriate adjustment of stimulation parameters based on confirmed fusion detection such that fusion re-occurrence is minimized.

The invention relates to a multiple-laser radar raster map merging system based on a pilotless automobile. The multiple-laser radar raster map merging system based on the pilotless automobile comprises a one-line laser radar and a four-line laser radar, the two of which are mounted in front of the pilotless automobile, an eight-line laser radar mounted at the roof of the automobile, and a one-line laser radar mounted at the tail of the automobile; the laser radars are connected with a first industrial personal computer by use of a switch and by virtue of Ethernet; the data of the laser radar are transmitted to the first industrial personal computer by use of the switch and by virtue of the Ethernet, and the first industrial personal computer is used for analyzing and preprocessing the data; data are processed for different laser radars, respectively, and rasterization coding is performed on valid data and the coded values are transmitted to the first industrial personal computer in charge of data fusion by virtue of the Ethernet; next, data fusion is carried out by use of a raster map merging method and the rasterization coding is performed on the data, and finally, the coded values are transmitted to a second industrial personal computer by virtue of the Ethernet. The multiple-laser radar raster map merging system is used for solving the problem that the pilotless automobile and an assistant-driving automobile collide with a barrier, and therefore, the safety of the automobile in the driving process is improved.

There is provided a metal powder for use in a selective laser sintering method for producing a three-dimensional shaped object, wherein the metal powder comprises a powder mixture of a precipitation-hardening metal composition. In particular, the metal powder of the present invention is configured to have a Fe-based component powder and a Ni-based component powder which are individually included in the powder mixture wherein a powder made of an alloy of Fe-based and Ni-based components is not included as a main powder in the powder mixture.

The disclosure relates to a laminated, thermoformable barrier film useful as a peelable surface liner, such as in containers and other shaped articles. The laminated film includes at least two layers, including a distal layer and a medial layer. The medial layer includes an odor-resistant polymer barrier layer that inhibits passage of gases and odors therethrough. The distal layer includes a polymer layer that inhibits permeation of a liquid through to distal layer from a contact face thereof to the barrier layer. Optionally, the distal layer can include a scratch resistant layer. The laminated film can also include a proximal layer that includes a layer of a pliable polymer. The laminated film can be included as a surface liner, or stack of surface liners, on a thermoformed article or on a sheet that can be thermoformed. The laminated sheets have multiple uses, including as liners for food service containers. In such containers, the barrier layer of the laminated sheets can inhibit penetration of the liner by odors or tastes from food items contained therein and can also prevent liquid saturation of the barrier layer of the sheets, which could otherwise limit the odor-resistant properties of the sheets.

This method provides a method for reducing HIV-1 viral load in an HIV-1-infected human subject which comprises administering to the subject at a predefined interval effective HIV-1 viral load-reducing doses of (a) a humanized antibody designated PRO 140, or of (b) an anti-CCR5 receptor monoclonal antibody. This invention also provides a method for inhibiting in a human subject the onset or progression of an HIV-1-associated disorder, the inhibition of which is effected by inhibiting fusion of HIV-1 to CCR5+CD4+ target cells in the subject. This invention also provides a method for treating a subject infected with HIV-1 comprising administering to the subject (a) a monoclonal antibody which (i) binds to a CCR5 receptor on the surface of the subject's CD4+ cells and (ii) inhibits fusion of HIV-1 to the subject's CCR5+CD4+ cells, and (b) a non-antibody CCR5 receptor antagonist, in amounts effective to treat the subject.

A group of compounds that inhibit HIV replication by blocking HIV entry was identified. One representative compound, designated NB-206, and its analogs inhibited HIV replication (p24 production) with IC50 values at nanomolar levels. It was proved that NB-206 and its analogs are HIV entry inhibitors by targeting the HIV gp41 since: 1) they inhibited HIV-mediated cell fusion; 2) they inhibited HIV replication only when they were added to the cells less than one hour after virus addition; 3) they blocked the formation of the gp41 core that is detected by sandwich enzyme linked immunosorbent assay (ELISA) using a conformation-specific MAb NC-1; and 4) they inhibited the formation of the gp41 six-helix bundle revealed by fluorescence native-polyacrylamide gel electrophoresis (FN-PAGE). These results suggested that NB-206 and its analogs may interact with the hydrophobic cavity and block the formation of the fusion-active gp41 coiled coil domain, resulting in inhibition of HIV-1 mediated membrane fusion and virus entry.

The inverter has a plurality of arms for conducting or cutting off a current and each arm has a switching device and a first and a second wiring layer for connecting the switching device. The first and second wiring layers of each arm are respectively formed on insulating substrates, and one face of the switching device is fixed to the first wiring layer, and the second wiring layer and the other face of the switching device are electrically connected by a laminal conductor, and the laminal conductor has a first and a second connection, and the first connection of the laminal conductor is fixed to the other face of the switching device, and the second connection of the laminal conductor is fixed to the second wiring layer.Thereby, a large current of the inverter can be realized and the assembly capacity of the inverter or the vehicle drive unit will be improved.

The invention discloses a double-ultrasonic-high-frequency induction combined precision micro-connection device, which comprises a rack, a driving mechanism, a transmission mechanism, an upper ultrasonic vibration system, a high-frequency induction self-heating device, a lower ultrasonic vibration system, a workbench and a power supply, wherein the driving mechanism and the transmission mechanism are arranged on the rack; the upper ultrasonic vibration system is connected with the transmission mechanism; the high-frequency induction self-heating device is connected with the output end of the upper ultrasonic vibration system; the lower ultrasonic vibration system is arranged below the upper ultrasonic vibration system; the workbench is arranged above the lower ultrasonic vibration system; and the upper ultrasonic vibration system, the high-frequency induction self-heating device and the lower ultrasonic vibration system are connected with the power supply. According to the device, dual-ultrasonic vibration and heat energy are combined, so that the phenomenon that a workpiece to be connected is fused or damaged by over-temperature when only the heat energy is used is avoided, the problems of high unsoldering rate and incomplete insulating layer removal of ordinary ultrasonic hot pressure welding are also solved, the working efficiency is improved, and the production cost is lowered. In addition, the invention also discloses a method for performing double-ultrasonic-high-frequency induction combined precision micro-connection by adopting the device.

A thermal transfer image-receiving sheet is provided which causes none of a dimensional change, curling, misregistration of image and can produce a printed image having satisfactory image quality and density. The thermal transfer image-receiving sheet comprises: a paper substrate; and a dye-receptive layer provided on one side of the substrate, a water vapor barrier layer composed mainly of a resin being provided on at least the side of the thermal transfer image-receiving sheet remote from the dye-receptive layer.

The present invention relates to compounds of formula I:in which n, m, X, Y1, R1, R2, R3, R4 and R5 are defined in the Summary of the Invention; capable of being both potent antagonists and degraders of estrogen receptors. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with aberrant estrogen receptor activity.

Disclosed is a method for producing a glass, wherein a molten glass is obtained by melting and refining a glass starting material and the molten glass is molded, thereby producing a glass molded body composed of an optical glass. The method for producing a glass is characterized by comprising preparation of a glass starting material so as to obtain an oxide glass which contains, in cationic percent, 12-65% of B3+, 0-20% of Si4+, 0-6% of Ge4+, 15-50% of La3+, Gd3+, Y3+, Yb3+, Sc3+ and Lu3+ in total, 4-54% of Ta5+, Zr4+, Ti4+, Nb5+, W6+ and Bi3+ in total, 0-35% of Zn2+, 0-9% of Li+, Na+ and K+ in total and 0-15% of Mg2+, Ca2+, Sr2+ and Ba2+ in total, with the sum of all cationic components being 99-100%. The method is also characterized in that the glass starting material contains a carbonate and a sulfate.

The inverter has a plurality of arms for conducting or cutting off a current and each arm has a switching device and a first and a second wiring layer for connecting the switching device. The first and second wiring layers of each arm are respectively formed on insulating substrates, and one face of the switching device is fixed to the first wiring layer, and the second wiring layer and the other face of the switching device are electrically connected by a laminal conductor, and the laminal conductor has a first and a second connection, and the first connection of the laminal conductor is fixed to the other face of the switching device, and the second connection of the laminal conductor is fixed to the second wiring layer. Thereby, a large current of the inverter can be realized and the assembly capacity of the inverter or the vehicle drive unit will be improved.

The invention discloses a high-flux cell electrical fusion microfluidic chip device based on a microporous microelectrode array, which consists of a microelectrode microporous array chip and a microfluidic cover plate with top electrodes. In the invention, a micro electro mechanical system (MEMS) processing technique is adopted, and a microporous microelectrode array is constructed on a quartz substrate by using both a microelectrode array and a polymer microporous array; the microporous microelectrode array can better control cell pairing, so that a pair of cells fuses in each micro pore; the array structure can improve the flux of cell fusion; and the materials used for making the device disclosed by the invention have high biocompatibility and corrosion resistance and can ensure the reliability of chip and improve the safety of cell fusion. The device can be widely used in fields of genetics, animal and plant distant hybridization breeding, development biology, medicine screening, preparation of monoclonal antibody, mammalian cloning and the like.

The shaft and the bearing are capable of reducing vibration and noise of a motor. The shaft comprises: a shaft proper; and a sliding section provided to the shaft proper, the sliding section including carbon nano fibers or carbon nano tubes. On the other hand, the bearing comprises: a bearing proper; and a sliding section provided to the bearing proper, the sliding section including carbon nano fibers or carbon nano tubes.

The invention discloses a DDAG-based SVM multi-class classification active learning algorithm. The active learning through is adopted in the multi-class SVM learning process, the defects that according to the traditional 'one-to-many' or 'one to one' multi-class classification method, large amount of indivisible points or decision blind areas are provided during sample testing are utilized, the active learning algorithm based on the 'o-v-o' classification decision blind areas is provided, samples with the 'highest uncertainty' of the indivisible points or decision blind areas corresponding to a current learning device are selected actively, according to the limitation caused by the single active learning strategy during active learning, a multi-strategy integration active learning method on the basis of posterior probability and similarity measurement uncertainty is provided in the multi-class SVM learning process, the two active learning methods are combined effectively, the sample labeling load is reduced in the multi-class SVM learning process, the learning sample labeling cost is reduced, and an SVM classification device with the best performance can be obtained through the least labeled sample training.

The invention relates to an integral rigid runner droplet digital PCR system. The system comprises a power device, a droplet generation device, a rigid thermal circulation runner, a thermal circulation temperature control module, a fluorescent detection controller and a PC control module. A rigid thermal circulation pipeline has high heat conducting performance, and a rigid wall surface has low roughness and small relative deformation. The integral rigid runner droplet digital PCR system can be used for online detecting a droplet in real time by adopting the droplet generation device with a high loading capacity and a terminal fluorescent detection system, and has the characteristics of flexible temperature control, safety, no need of a special PCR reaction chip, high fluorescent detection flux, high sensitivity and the like; and the system can avoid the problems of measurement accuracy reduction and the like caused by droplet breakage and mutual fusion among droplets since the traditional droplet digital PCR equipment needs to manually transfer droplets in different reaction modules. The whole system forms a highly-integrated design by droplet generation, PCR reaction thermal circulation and terminal droplet fluorescent real-time online detection.

The invention provides a cooling device for a high-power optical fiber laser or an amplifier. The length of optical fibers arranged in the cooling device is variable, and the cooling device can cool a pump coupler arranged in the high-power optical fiber laser or the amplifier when cooling the optical fibers. The cooling device comprises a cooler pan and a heat conducting cover plate, wherein the cooler pan is a metal block provided with a flat surface; an input concave groove, a coupler concave groove, a helical line-shaped concave groove, a plurality of rewound concave grooves and a plurality of output concave grooves are engraved on the flat surface; the heat conducting cover plate is a metal block provided with a flat surface; and the flat surface of the heat conducting cover plate is not smaller than that of the cooler pan. When the integral cooling device for the high-power optical fiber laser or the amplifier is used, doped optical fibers can be returned to an adjacent former ring through the rewound concave groove when wound in the helical line-shaped groove, and the rewinding can be performed multiple times in the same rewound concave groove.

The invention consists of a wireless access sub network used to implement wireless access and a management control sub network used to manage and control the wireless access sub network. The method includes following steps: the wireless digital broadcast layer located at upper layer broadcasts synchronizing and control messages to the wideband wireless bearer layer located at intermediate layer, the mobile communication layer located at lower layer, and all kinds of terminal covered by those layers and cooperating with one or more layers in working; makes the synchronous measurement and adjustment for the network above; measures the difference between the arrival times in mobile communication layer by using fix time slot; in term of the fix time slot, implements the dynamical allocation and multiplexing for frequency spectrum in order to locate the mobile station.

Process for the effective production of very wear-resistant layers in the thickness range of 0.2 to approx. 3 mm by way of inductively supported surface layer modification. It can be used particularly advantageously for the protection of components of hardenable steels and cast iron with abrasive, corrosive, high-temperature corrosive or mineral sliding wear loading. With the process according to the invention a local two-stage inductive short-time preheating takes place directly before the surface layer coating. Due to the invention it is possible to coat even hardenable steels or other materials difficult to coat without cracking. Furthermore, even harder coating materials susceptible to cracking which provide better wear-resistances can be used. In addition, process speeds and surface coating performances can be achieved that are higher by a factor of 10 compared with conventional laser build-up welding. This abstract is neither intended to define the invention disclosed in this specification nor intended to limit, in any manner, the scope of the invention.

The invention relates to a preparation method of a high-temperature-resisting aerogel material. The method comprises the following steps: (1) preparing sol; (2) carrying out a nano-crystal assemblingprocess to prepare aerogel wet gel which takes an oxide nano-crystal as a framework; (3) preparing an aerogel material; (4) carrying out a heat treatment process to prepare the high-temperature-resisting aerogel material. According to the preparation method provided by the invention, a nano-crystal assembling technology and heat treatment are combined to prepare the high-temperature-resisting aerogel material with a microcosmic core-shell structure; the core-shell structure forms a network framework under high temprature so that the growth of the oxide nano-crystal is inhibited and the shrinkage problem caused by the fact that the structure of oxide aerogel collapses in a high-temperature utilization process is effectively solved. The aerogel material prepared by the preparation method hasa good high-temperature-resisting property; the heat-resisting temperature is 1000 DEG C or more and the high-temperature-resisting aerogel material even can bear the high temperature of 1300 DEG C or more.

A fuse-containing box is formed by placing a battery fuse and a bus bar connected to a terminal of the battery fuse on a supporting plate and by mounting a lower case and an upper case on the supporting plate. The fuse-containing box is mounted on an upper surface of a battery. A battery terminal to be fixedly fitted on a battery post projecting from the upper surface of the battery is fastened to the bus bar to electrically connect the battery fuse and the battery to each other. The lower case and the upper case are formed from a polypropylene-based resin. The supporting plate on which the battery fuse and the bus bar are mounted is formed from a heat-resistant nylon-based resin.

The disclosure relates to containers and other shaped articles that have a relatively thick substrate layer and one or more relatively thin liner sheets peelably adhered thereto. Animal litter can be placed atop the liner sheets, preferably in a concave portion to contain the litter. The liner sheets have perforations extending therethrough that permit the passage of non-soiled litter, but do not permit the passage of at least one of animal feces and soiled animal litter, such as clumps of litter and urine. After an animal has deposited waste on or in the litter, the liner sheet can he peeled from the container and waste unable to pass through the perforations can be collected.