The invention relates to the technical field of 
enzyme preparation, in particular to comprehensive 
enzyme powder with a 
lipolysis function and a preparation method of the comprehensive 
enzyme powder with the 
lipolysis function. The comprehensive enzyme 
powder is prepared from, by weight, 1-5 parts of compound 
decomposition enzyme, 10-30 parts of natto, 50-70 parts of vegetables, 80-100 parts of fruits, 10-30 parts of edible fungi, 10-15 parts of medicinal and edible 
traditional Chinese medicine extracts, 5-10 parts of 
mushroom extracting liquid and 40-80 parts of pineapple powder by addition of enzyme strains. Compared with the prior art, the comprehensive enzyme powder with the 
lipolysis function has the advantages of diversity, balance and easiness in absorption. The preparation method has the advantages that 
fungal polysaccharides are extracted through combination of ultrasonic 
waves and an enzymolysis method, fungal 
cell wall crushing effects are enhanced by ultrasonic 
waves to increase 
polysaccharide dissolution rate, 
cell walls are subjected to further enzymolysis by the enzymolysis method to enable intercellular polysaccharides to be released sufficiently, and accordingly the preparation method is efficient, time saving, labor saving, higher in 
polysaccharide yield and purity and suitable for large-scale production and application.