The invention discloses a 
neopentyl glycol condensation hydrogenation production process which comprises the following steps of: 1) condensation, that is, performing a 
condensation reaction of 
isobutyraldehyde with a 
methanol aqueous solution of 
formaldehyde, delivering the mixed condensation products into a condensation circulation 
tower for separation, allowing hydroxypivalaldehyde to enter a hydrogenation reactor from the condensation circulation 
tower, allowing a gas-phase component to flow back to a 
raw material mixing zone for mixing, and to enter a condensation reactor; 2) hydrogenation, that is, performing a 
hydrogenation reaction of the hydroxypivalaldehyde with 
hydrogen, delivering the products into a gas-liquid separation tank, allowing a gas-phase component to flow back to the hydrogenation reactor, allowing the liquid-phase 
neopentyl glycol crude product to enter a 
saponification reactor; 3) refining, that is, performing a 
saponification reaction of the 
neopentyl glycol crude product, allowing the product to enter a low-boiling-point substance fractionating 
tower, allowing a liquid-phase component at the tower bottom to enter a flash tank, allowing a liquid-phase component at the flash tank bottom to enter a pH adjusting tank, adjusting the pH to 6.5-7, allowing the product to enter a 
falling film evaporator, allowing a gas-phase component at the top of the 
falling film evaporator to enter a 
drying tower, then to enter a rectifying tower for refining so as to obtain neopentyl glycol. The process of the invention is high in neopentyl glycol yield, and simple and effective in separation purification process.