The invention relates to the technical field of 
medical instruments, in particular to a method for designing a 
femoral stem prosthesis, and solves the problem that the existing 
femoral stem prosthesisis made of a material with high 
elastic modulus, so that the difference between the high elasticity and that of human 
femur is large, resulting in different degrees of 
stress shielding, the problem that the manufacturing process can hardly satisfy the manufacture requirement on customization and complex interior structure, so that high matching prostheses meeting the individual needs cannot be implemented, and other problems. The method comprises establishing an STL model, carrying out 
simulation operation to establish a model, establishing a finite element 
mesh model, establishing 
model material properties, establishing boundary conditions, setting 
topological optimization parameters and extracting an STL format file from the optimized model; and carrying out post-
processing of fairing and the like to remove chessboard patterns in the 
software Inspire to obtain an optimized 
femoral stem model; manufacturing an optimized 
prosthesis with ti6al4v, and finishing the manufacture by meansof an 
electron beam melting technique through an Arcam Q10 plus 
metal printer. The method for designing the prosthetic stem structure adopts integral forming and has no need for 
cutting, splicing andother 
processing, and the structure is good in 
biocompatibility.