94results about How to "Shorten survival time" patented technology

The present invention is directed to the identification of predictive markers that can be used to determine whether patients with cancer are expected to demonstrate long term or short term survival times. In particular, the present invention is directed to the use of certain individual and / or combinations of predictive markers, wherein the expression of the predictive markers correlates with expected short term or long term survival. Thus, by examining the expression levels of individual predictive markers and / or predictive markers comprising a marker set, it is possible to determine predicted patient survival.

Compositions which include platelet-rich plasma and fibroblast cells are disclosed for the treatment of skin. In particular, administration of platelet-rich plasma in a dermatologically acceptable carrier repeatedly to skin is disclosed to reduce the appearance of wrinkles.

The invention discloses a routing method of a self-adapting self-organized network in a cognitive network, mainly solving the problem that the traditional cognitive network routing methods lack of network QoS (quality of service) guarantees. The routing method comprises the following steps of: sending RREQ information by a source node by adopting a broadcast flooding method; when a relay node transmits the RREQ information, extracting the state of a network node, estimating the waiting time delay of the node in the network and adding the waiting time delay during transmitting the RREQ information; after a target node receives the RREQ information, sending the RREQ information according to a principle of firstly returning early arrived information and establishing a route; after establishing the route, repeatedly sending the same RREQ information to the resource node by the target node to update network state information; and detecting the quality of the route and determining whether to increase or reduce the life time of the route or not. The method has the advantages of short data transmission time delay, small packet loss, high route efficiency and large network load capacity and can be applied to cognitive radio networks.

The present invention relates to a route choice method of a mobile ad-hoc network based on bandwidth constraint and minimum load, which includes three steps. Firstly, when a node needs to transmit services to another node, the node broadcasts routing request packets; secondly, when receiving a routing request message, an intermediate node compares the addresses of the intermediate node and the destination node; thirdly, when receiving the routing request from the source node, the destination node checks whether the current time is less than the time spent in receiving the routing request within the specified time. In a mobile ad-hoc network, the bandwidth resource is hard to determine due to the dynamic change of topological structures, the energy of the heavily loaded nodes in a network is rapidly depleted due to the unbalanced load distribution, and as a result the connectivity of the network is rapidly weakened, which finally shortens the total survival time of the network; the present invention resolves the problem. The present invention is compared with the existing AODV protocol by using the NS2 simulation tool, and the simulation results show that the BLLM excels the AODV in terms of packet delivery rate, packet loss rate, throughput, etc.

The invention relates to a method used for saving node energy in a delay tolerant network and an intermittent connection network, belonging to the field of network communication technique. The method comprises the steps as follows: a source node queries a node neighbor list; if no destination node information exists, the message is temporarily memorized in a node buffer; the non-empty nodes in the buffer periodically send exploration information which is used to exchange a message list and a message delivery acknowledgement list; when the node sending the exploration information receives a return information, the buffer is actively maintained according to the message delivery acknowledgement list carried in the return information and a message is sent by the node; after an intermediate node successfully transmits the message to the destination node, the node adds corresponding records into the message delivery acknowledgement list memorized locally and deletes the message from the buffer. The method can effectively reduce the quantity of the redundant nodes, improves the performance of the whole network and prolongs the life period.

The invention concerns the use of certain compounds related to fatty acids to control nematodes that infest plants or the situs of plants. Nematodes that parasitize animals can also be controlled using the methods and composition of this invention. Certain of the useful compounds are fatty acid esters that are predicted inhibitors of nematode delta-12 fatty acid desaturases and can be, for example, from C16 to C20 in length.

The invention relates to a method for the host selection and address configuration manner switchover of an IPv6 (Internet Protocol version 6) network. According to the method, a Control flag and a Single flag which are used for normalizing and flagging the host selection and the address configuration manner switchover are additionally arranged in an RA (Router Advertisements) message of a ND (Neighbor Discovery) protocol, and then, the following operations are executed: a router sets the Control and Single flags and other fields; the router regularly sends the RA message to a host on an IPv6 link or sends the RA message to the IPv6 link after an RS (Request) is received; after the RA message is received, the host parses the Control and Single flags and records the Control and Single flags in status bits; the host decides to configure an IPv6 address by using an SLAAC (Stateless Address Auto-Configuration) mechanism or a DHCPv6 (Dynamic Host Configuration Protocol for IPv6) according to the selection criteria for a host address configuration manner set by the Control and Single flags; and if the host already configures the IPv6 address by using certain manner, the address configuration manner set by the flags is switched to according to the criteria. The method has the advantages that the demands that the host configures the IPv6 address by using the two address configuration manners in a coordinating manner can be met, and the requirements on network address management and network renumbering can also be met.

The invention discloses a spine-free zanthoxylum bungeanum cultivation method, which comprises land selecting and preparation, seedling raising, ear cutting and grafting, field planting, cultivation management, and seedling raising of spine-free zanthoxylum bungeanum, wherein a seed stirring agent is used during the seedling raising process, and during the ear cutting and grafting, the scion male parent is soaked with an essence liquid so as to improve the healing and scion survival rate of the joint part. According to the present invention, with the grafting of more than three generations, the spine-free or micro-spine characteristic can be stabilized, and the new grafted seedling has characteristics of high survival rate, strong branches, convenient transplanting and good quality.

The invention concerns the use of certain compounds related to fatty acids to control nematodes that infest plants or the situs of plants. Nematodes parasitizing animals can also be controlled using the methods and composition of this invention. The useful compounds are inhibitors of nematode delta-12 fatty acid desaturases and can be, for example, from C16 to C20 in length. A feature of these compounds is that their inhibitory effect on the activity of a nematode delta-12 desaturase, or on the viability or fecundity of a nematode, is smaller in the presence of the product of a delta-12 fatty acid desaturase (e.g., linoleate) than in the presence of the substrate of the enzyme (e.g., oleate).

The invention discloses a directional air transmission device and an air disinfection system for prevention and control of pathogenic microorganisms in a sick area. The device comprises an air-cooledheat pump fresh air unit module, an ultraviolet disinfection module and an air purification pipe connected in sequence outside the sick area, also comprises a slot air supply outlet that is located above the side wall in the sick area, is connected to the air purification pipe and supplies air vertically downward, and also comprises an arc-shaped deflector located below the slot air supply outlet,wherein the arc-shaped deflector is recessed downward, the curved arc also comprises a negative pressure exhaust device located below the opposite wall of the side wall, and clean fresh air is outputthrough the slot air supply outlet to the arc-shaped deflector for deflecting and conveying, and then is filtered and discharged by the negative pressure exhaust device. Through the reasonable setting of the component structure, a directional clean air belt is formed and sent directly to the breathing area of personnel, which solves the unorganized spread and pollution of harmful gases and viruses in the hospital ward, and solves the problems that the HVAC system can accurately meet the standards when the air quality requirements change in the hospital, and that the ventilation effect is poor.

The invention discloses an ISP anomalous traffic detection method and a system, belonging to the field of information safety. The method comprises the following steps: capturing a network data packet; distinguishing a dangerous network data stream to determine a dangerous area; extracting the dangerous mode of the dangerous network data stream sent to the dangerous area; matching the dangerous mode with a memory detector, and meanwhile updating the antibody concentration of the memory detector; and according to the antibody concentration of the memory detector, determining the value at risk of the anomalous traffic of a network. The system of the invention comprises a network data packet acquisition module, a danger identification module, a dangerous area identification module, a network anomalous traffic mode identification module and a danger assessment module. The invention can solve the problems of low misinformation rate, poor self-adaption ability or no self-adaption ability. The invention also adopts the tolerance mechanism of the network anomalous traffic to cause the system to have the ability of detecting the anomalous network traffic caused by a large number of sudden normal network accesses.

The invention discloses a sensor emission energy consumption optimization method of a multi-antenna unmanned aerial vehicle data acquisition system, and is suitable for an Internet-of-Things communication scene. The data acquisition system comprises a single multi-antenna unmanned aerial vehicle and a plurality of sensors. The single multi-antenna unmanned aerial vehicle serves a plurality of ground sensor nodes as an air base station, and the method comprises the following steps: establishing a channel fading model and a corresponding system model according to geographic positions of the sensor nodes and the unmanned aerial vehicle and an air-to-ground wireless channel model; establishing an optimization problem according to the flight time constraint of the unmanned aerial vehicle, the transmitting power constraint of the sensor node and the link transmission rate constraint, wherein the optimization problem minimizes the maximum energy consumption of the sensor node by optimizing the speed of the unmanned aerial vehicle and the signal transmitting power of the sensor node; and solving the optimization problem to obtain an optimal navigation speed of the unmanned aerial vehicle and a sensor node power distribution scheme. According to the invention, the energy consumption can be minimized, and the cruising ability of the sensor node equipment is prolonged.

The invention discloses an efficient composite fire extinguishing agent and a preparation method thereof, and relates to the technical field of firefighting. The fire extinguishing agent comprises, byweight, 28-36 parts of heptafluoropropane, 40-48 parts of 1,1,2,2,3,3,4-heptafluorocyclopentane, 4-8 parts of liquid nitrogen, 6-12 parts of ammonium bicarbonate, 1-5 parts of calcium carbonate, 1-3parts of potassium sulfate, 2-6 parts of talcum powder and 1-5 parts of diatomite. The fire extinguishing agent has the advantages of combination of the fire extinguishing advantages of several physical and chemical fire extinguishing agents, improved fire extinguishing efficiency, low corrosivity, long atmospheric survival time and low greenhouse effect potential value.

The invention provides a high-pollution building space exhaust disinfection and purification system and method. The system comprises a pollution region negative pressure metal ventilation pipe, and any position of the pollution region negative pressure metal ventilation pipe is communicated to the inlet end of a high-resistance ventilation pipeline with a heat insulation and insulation layer. Theoutlet end of the high-resistance ventilation pipeline with the heat insulation and insulation layer is connected to the inlet end of an outdoor negative pressure metal ventilation pipe through an electric backflow prevention valve, and the outlet end of the outdoor negative pressure metal ventilation pipe is connected to an extraction opening of an efficient frequency conversion draught fan. A plurality of virus killing devices are sequentially arranged at the rear end of the efficient variable-frequency draught fan. By means of the system and method, air possibly containing viruses in a high-pollution building space is subjected to high-temperature disinfection and sterilization through an electric heating pipeline, then the air subjected to high-temperature disinfection and sterilization is guided to an outdoor multi-virus disinfection and sterilization device through the negative pressure pipeline to conduct diversified thorough disinfection and sterilization on the introduced air,and the viruses in the air in the high-pollution building space can be thoroughly removed.

The invention belongs to the technical field of detection kits, and particularly relates to a kit for aided-diagnosis and prognostic evaluation on glioblastoma based on a gene CLCF1 and a use method thereof. The kit comprises a PCR (polymerase chain reaction) primer pair for amplifying the gene CLCF1 and a PCR primer pair for amplifying a housekeeping gene GAPDH. The kit has the advantages that the obvious difference of the gene CLCF1 in transcription expression levels of LGG (brain lower grade glioma) and GBM (glioblastoma multiforme) is found for the first time, the prognostic condition of apatient with the glioblastoma is well judged by the expression level of the gene CLCF1, and the gene CLCF1 can be used as the index for independently judging the prognostic condition of the glioblastoma after determining by Cox multi-factor regression analysis; after the expression condition of the transcription level of the gene CLCF1 is detected, the severity of the glioblastoma can be diagnosed, and the prognostic condition of the patient can be predicted.

The invention belongs to the technical field of air purification, and particularly discloses a filter screen taking a nanometer material as a filter. The filter screen comprises a felt type non-woven fabric and filter substances adhered to the felt type non-woven fabric, wherein a woody activated carbon powder is adsorbed on one side of the felt type non-woven fabric, while a nano-scale titanium dioxide powder is adsorbed on the other side of the non-woven fabric; and the felt type non-woven fabric is covered on the outer sides of the woody activated carbon powder and the titanium dioxide powder respectively and is in press-fit to form an integral filter screen. The nanometer material filter screen disclosed by the invention adopts the nano-scale titanium dioxide as a strong oxidant and a strong reducing agent, so that the filter screen can effectively isolate and kill hazardous substances and harmful bacteria, can shorten survival time of viruses in air, can be applied as an isolation material for sealing doors and windows in various places such as a hospital, a lab, and a dormitory, furthermore can be used as a biochemical isolation material, and has the advantages of light weight, convenience in installation and use, practicability in the effect and the like.

The invention discloses a water treatment system and method. The system comprises a water quality monitoring device, a water quality evaluating device and a water body purifying device, wherein the water quality monitoring device is installed in a water body to be detected and used for obtaining various physical, biological and chemical indexes of the water body to be detected; the water quality evaluating device is used for comparing the various physical, biological and chemical indexes obtained by the water quality monitoring device with the water quality standard to determine whether the water body needs to be treated or not; the water body purifying device is arranged on the water quality monitoring device to be communicated and used for receiving the water body which is determined by the water quality evaluating device and needs to be treated and purifying the water body through at least one treatment device. According to the film and gas separation technology, by applying the film diffusion principle, poisonous and harmful ammonia nitrogen and carbon dioxide in aquatic products in the water body are removed in a physical mode, chemical and biological removal are avoided, the system is applicable to the fast-pace business traffic, and no other chemical matter in the water body is added.

The invention belongs to the technical field of detection kits, and particularly relates to a kit for aided-diagnosis and prognostic evaluation on non-small cell lung cancer based on a gene GALNT2 anda use method thereof. The kit comprises a PCR (polymerase chain reaction) primer pair for amplifying the gene GALNT2 and a PCR primer pair for amplifying a housekeeping gene GAPDH. The kit has the advantages that the obvious difference of the gene GALNT2 in transcription expression levels of non-small cell lung cancer and normal paracancerous tissue is found for the first time, the prognostic condition of a patient with the non-small cell lung cancer is well judged by the expression level of the gene GALNT2, and the gene GALNT2 can be used as the index for independently judging the prognosticcondition of the non-small cell lung cancer after determining by Cox multi-factor regression analysis; after the expression condition of the transcription level of the gene GALNT2 is detected, the non-small cell lung cancer can be diagnosed, and the prognostic condition of the patient can be predicted.

The invention relates to the technical field of make-up tools, and particularly discloses animal hair-like polyester filament cosmetic brush hair and a production process thereof. The animal hair-like polyester filament cosmetic brush hair is prepared from the following raw materials in parts by weight: 60-70 parts of polyester resin, 3-6 parts of nano pearl powder, 2-6 parts of titanium dioxide, 19-25 parts of an antibacterial agent and 1-2 parts of a lubricating agent; and the antibacterial agent is prepared from the following raw materials in parts by weight: 5-10 parts of polyester resin, 5-8 parts of a graphene oxide / silver compound, 2-3 parts of organic bentonite, 1-3 parts of chitosan oligosaccharide and 2-4 parts of nano bamboo charcoal powder. The preparation method comprises the steps of mixing, melt spinning, shredding, hair peak making and after-finishing. The antibacterial agent is added into the raw materials of the cosmetic brush hair, so that the antibacterial performance of the cosmetic brush hair is improved.

The invention discloses a soilless cultivation and seedling raising method for panicled fameflower. The soilless cultivation and seedling raising method for the panicled fameflower includes the following steps of 1 cutting processing, 2 nutritional pot preparation, 3 cutting management and 4 transplanting cultivation. The soilless cultivation and seedling raising method for the panicled fameflower simply and efficiently performs cutting propagation without transplanting cultivation, the survival time is shortened to be 3-4 days, a seedling raising period is short, the survival rate is 95-97%, the panicled fameflower is strong in resistance, vigorously grow and have thick and strong stems, lodging resistance and expanded roots, and edible parts are increased. Rooting liquid contains rich small molecules, is safe, non-toxic and high in utilization and absorption rate and promotes rooting. A cultivation matrix makes the panicled fameflower grow in a fixed mode, can absorb harmful substances in the process of adsorption and growth, is antibacterial and disinfectant, water-retaining, air-permeable, balanced in nutrition and high in absorption efficiency and controls sustained release of a fertilizer, and the planting cost is saved. Pesticides are not needed in the whole process, the soilless cultivation and seedling raising method is safe and environmentally friendly, does not cause pesticide residues and improves the panicled fameflower.

Indicators that can guide clinical decisions in cancer, particularly posttranslational modification of proteins which result in altered prognosis and differential sensitivity to targeted cancer therapy, are provided. In particular, monitoring of phosphorylation of PTEN may be utilized to predict or assess drug response, drug sensitivity, and clinical outcome. Modulation of PTEN phosphorylation may be utilized to alter sensitivity and outcome in cancer patients. Posttranslational modification of PTEN, particularly phosphorylation, is correlated with resistance to targeted cancer therapy, including EGFR inhibitors, and with reduced survival prognosis. Methods and assays for determining phosphorylation of PTEN, particularly Y240 phosphorylation, are provided. Methods for sensitizing tumors to inhibition and targeted therapy by modulating PTEN phosphorylation are provided.

The invention provides a method for detecting the safety of exogenous genes in transgenic crops on soil nematodes. The method comprises the following steps: obtaining identical short fragments of the exogenous genes in the transgenic crops and genomes in caenorhabditis elegans through bioinformatic analysis, feeding the caenorhabditis elegans by cloning and converting the short fragments, and detecting the safety of the exogenous genes on the nematodes according to the phenotypic difference of the caenorhabditis elegans. In the past, the safety evaluation on the transgenic crops focuses on the influence of feeding foreign protein on non-target organisms. The method is used for detecting the safety of the exogenous genes on the nematodes which are important framers of soil eco-systems, and filling the blank of the safety evaluation field of the transgenic crops. The method has the advantages that RNAi (Ribonucleic Acid interference) is carried out by adopting a feeding method, special reagents and instruments are not needed, nematode feeding is easy, and the method is simple and practicable.

Compositions and processes for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include oxazoles, oxadiazoles and thiadiazoles.

The invention discloses a double-gene-deficient Salmonella enteritidis strain and an establishment method thereof, and a vaccine containing the double-gene-deficient Salmonella enteritidis strain. The double-gene-deficient Salmonella enteritidis strain is a Salmonella enteritidis strain of which rfaH gene and sopB gene are knocked out. According to the establishment method, a homologous recombination process and a sucrose-sensitive gene negative screening process are adopted to knock out the rfaH gene and sopB gene in the Salmonella enteritidis strain. The vaccine comprises the double-gene-deficient Salmonella enteritidis strain prepared by the method. The cellular immunity and mucosa immunity of the double-gene-deficient Salmonella enteritidis strain are enhanced; and the double-gene-deficient Salmonella enteritidis strain has favorable protective effects and favorable immune effects, has favorable removing effects in the host, can be colonized and removed in the body within 3-4 weeks, and thus, has excellent safety performance.

The invention discloses a biomass landfill management method which comprises a biomass landfill management system, wherein the biomass landfill management system comprises a computer, a plurality of data collection devices, a plurality of displayers, an input device and a printer. The data collection devices, the displayers, the input device and the printer are connected with the computer. Fixed gross of CO2 of photosynthesis of landfill plants of nations or areas is counted through the biomass landfill management system. Nations or areas with multiple landfill biomass can help nations or areas where tasks of greenhouse gas emission can not be finished, business of 'carbon emissions permit trading' can be promoted, and tasks of emission reduction are finished. An atmosphere greenhouse effect is relived step by step, glacier melting on at two poles is restrained, rising of a sea level is controlled, climate on the earth and biological diversity are maintained, and survival time of human beings on the earth is prolonged.

The invention relates to a lipstick with an antiviral effect. The lipstick contains an antiviral drug (remdesivir), and the content of the remdesivir in every 100g of the lipstick does not exceed 10g.After the lipstick is wiped on related parts, the propagation of viruses on exposed parts of the surface of a human body can be inhibited, the survival time of viruses is shortened, and the infectionrisk is reduced.

The invention belongs to the technical field of detection kits, and in particular relates to a glioblastoma auxiliary diagnosis and prognostic evaluation kit based on an FUCA1 gene and use method of the kit. The kit comprises a PCR (Polymerase Chain Reaction) primer pair for amplifying an FUCA1 gene and a PCR primer pair for amplifying a housekeeping gene GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase). According to the kit, the condition that FUCA1 gene has remarkably different transcription expression levels in LGG and GBM for the first time, meanwhile prognosis of a patient suffering from glioblastoma can be easily judged according to expression levels of the FUCA1 gene, and multi-factor regression analysis of Cox confirms that the FUCA1 gene can be used as an index of independent judgment prognosis of the glioblastoma. Namely, by detecting expression of the FUCA1 gene transcription level, the malignancy grade of a glioma patient can be diagnosed, and the prognosis situation of the patient can be predicted.

Compositions and processes for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include oxazoles, oxadiazoles and thiadiazoles.

The invention provides a system and method for exhausted air sterilization and aeration and comprehensive heating disinfection of a highly-contaminated building space. The system comprises a contaminated area negative pressure metal ventilation pipe, any position thereon communicates with an inlet end of a high-resistance thermal-insulation-layer-carried ventilation pipeline, an outlet end of thehigh-resistance thermal-insulation-layer-carried ventilation pipeline is connected to an inlet end of an outdoor negative pressure metal ventilation pipe through an electric anti-backflow valve, and an outlet end of the outdoor negative pressure metal ventilation pipe is connected with an exhaust port of a high-efficiency variable-frequency fan. Various virus killing devices are sequentially disposed at the rear end of the high-efficiency variable-frequency fan. The system disinfects the air that may contain viruses in the highly-contaminated building space at high temperature through an electric heating pipeline and then guides the air that is disinfected at high temperature to the various outdoor virus killing devices through negative pressure pipelines to diversely and thoroughly disinfect the guided air, thereby thoroughly removing viruses in the air in the highly-contaminated building space.

The invention belongs to the technical field of detection kits, and particularly relates to an auxiliary glioblastoma diagnosis and prognostic evaluation kit based on an IFI30 gene and a using method thereof. The kit comprises a PCR primer pair which amplifies the IFI30 gene and a PCR primer pair which amplifies a housekeeping gene GAPDH. The kit firstly discovers that the IFI30 gene has obvious difference on the transcriptional expression level in LGG and GBM, meanwhile the expression level of the IFI30 gene can well judge the prognosis of a glioblastoma patient, and the index, which can be used for independently judging the prognosis of glioblastoma, of the IFI300 gene is determined through a Cox multi-factor regression analysis, that is, the expression condition of the IFI300 gene transcriptional level is detected so that the kit can diagnose the malignant degree of the glioblastoma patient and predict the prognosis condition of the patient.