399 results about "Breath out" patented technology

The present invention includes systems and methods for monitoring endogenous compound concentration in blood by detecting markers, such as odors, upon exhalation by a patient, wherein such markers are the endogenous compound itself or result from the endogenous compound. In the case of olfactory markers, the invention preferably utilizes electronic sensor technology, such as the commercial devices referred to as “artificial” or “electronic” noses or tongues, to non-invasively monitor endogenous compound levels in blood. The invention further includes a reporting system capable of tracking endogenous compound concentrations in blood (remote or proximate locations) and providing the necessary alerts with regard to emergent or harmful conditions in a patient.

There is provided a system for the delivery of inhalable medicament comprising a monitor (40) for monitoring the breath cycle of a patient, a medicament container (2) having a release mechanism (4, 5) for releasing inhalable medicament therefrom, and an actuator (50) for actuating said release mechanism, the actuator (50) being actuable in response to a signal from the monitor (40). The monitor (40) provides the signal at a trigger point which is coupled to the end of the exhalation part of the breath cycle.

A small oxygen enriching apparatus which can supply oxygen-enriched gas at high flow rate without imparting unnatural sensation to a user, as well as a controller and recording medium therefore. In step 100, a judgment is made as to whether a flow rate set by use of a flow-rate setting unit 47 is equal to or less than a continuous base flow rate (2 liters / min). When the set flow rate is a low flow rate of not greater than 2 liters / min, breath-synchronized operation is not performed (continuous supply is to be performed), and therefore, in step 110, oxygen-enriched gas is supplied continuously at the set flow rate. When the set flow rate is a high flow rate of greater than 2 liters / min, breath-synchronized operation is to be performed (supply during the inhalation period only of each breathing cycle), and therefore, in step 120, oxygen-enriched gas is continuously supplied at the continuous base flow rate. In step 140, in order to perform breath-synchronized operation, control for opening and closing an electromagnetic valve 45 is performed. That is, oxygen-enriched gas is supplied during the inhalation period only of each breathing cycle, and supply of oxygen-enriched gas is stopped during the exhalation period.

An apparatus for measuring a quantity of an analyte, such as an aldehyde, contained in a breath sample includes a breath collection device and a measurement device. The breath collection device includes a breath inlet area, a breath outlet area, and a reaction chamber. The reaction chamber can include a reagent that is colorimetrically reactive with one or more aldehydes. The measurement device includes a light emitting device and a light measuring device and is configured to provide a quantitative value indicative of the amount of aldehydes present in the breath sample.

Provided herein is a novel breath test for assessing bacterial overgrowth. The test involves administration of a labeled sorbitol or sorbitol derivative to a subject and measurement of the label in breath and / or blood.

An apparatus and method to characterize NO gas exchange dynamics in human lungs comprising the steps of: (1) performing a series of breath hold maneuvers of progressively increasingly breath hold times, each breath hold maneuver comprising a) inhaling a gas, b) holding a breath for a selected time duration, and c) exhaling at a flow rate which is uncontrolled but which is effective to ensure evacuation of the airway space and (2) measuring airway NO parameters during consecutive breath hold maneuvers. As a result disease states of the lungs are diagnosed using the measured airway NO parameters.

An apparatus and method to characterize NO gas exchange dynamics in human lungs comprising the steps of: (1) performing a series of breath hold maneuvers of progressively increasingly breath hold times, each breath hold maneuver comprising a) inhaling a gas, b) holding a breath for a selected time duration, and c) exhaling at a flow rate which is uncontrolled but which is effective to ensure evacuation of the airway space and (2) measuring airway NO parameters during consecutive breath hold maneuvers. As a result disease states of the lungs are diagnosed using the measured airway NO parameters.

An apparatus and method of using an end-tidal gas value taken from an non-intubated patient that includes measuring a plurality of gas concentration values, determining an end-tidal gas value from the gas concentration values, and reporting the end-tidal gas value for a breath as the greater of either: (a) a maximum gas concentration values observed during such a breath, or (b) the end-tidal gas value reported for a previous breath decreased by a maximum allowable breath-to-breath percent change.

In order to provide an alcohol test device which can keep evidence that an identical person has been surely tested in an alcohol test, the alcohol test device includes an alcohol test unit which measures alcohol concentration from breath exhaled by a subject; a drinking determination unit which determines whether or not the subject is in a drunken state on the basis of a measurement result of the alcohol test unit; a camera unit which photographs a face image of the subject when the breath is exhaled into the alcohol test unit; a face authentication identical person determination unit which compares a face image photographed by the camera unit with a face image of the subject himself (herself) preliminarily photographed, and performs identical person authentication which determines whether or not the subject is the identical person; a result control unit which edits combining a result of identical person authentication by the face authentication identical person determination unit and a result of drinking determination by the drinking determination unit; and a result display unit which displays a result edited by the result control unit.

This invention relates to a method that comprises the introduction of a catheter via left subclavian vein, advancing into the right atrium and then positioning it in the inferior vena cava, just at the cava-diaphragm junction, where it is anchored at its extreme; and thereafter an external inflation of a balloon positioned in said catheter takes place through a physiological solution to reach a diameter corresponding to half the diameter of the inferior vena cava, resulting in hemi-occlusion in the expiration phase (breath-out) and total occlusion for a short period during the inspiration phase (breath-in), regulating (normalizing) the venous return and decreasing the cardiac volume overload, as a treatment for heart failure. The invention also comprises hydromechanics devices to normalize the venous return in the circulatory system. Said venous return is increased in 90% of patients with heart failure. In particular, it refers to a combined catheter with an inflatable balloon, producing said balloon a cyclical occlusion of the inferior vena cava (IVC). The said balloon is adaptable to the area of its location in the inferior vena cava, proximal to the right atrium (RA), which comprises of means for its fixation within said vein, as well as the capacity of modifying the volume in response to the requirements of the patient. This device is implanted for an extended period of more than three months. The final objective is to treat and stop the progression of heart failure.

An exhalation collected in a breath bag capable of expanding and contracting is sucked into a gas inlet vessel 21 with a given volume (Va), and then the gas inlet vessel 21 is communicated by means of valve V2 with a cell 11 that is maintained at an atmospheric pressure by being pre-filled with a sample gas or reference gas. After the communication, the gas pressure is measured by a pressure sensor 16 attached to the cell 11. Whether the exhalation collected in the breath bag is below a given amount or not can be accurately judged.

The invention relates to a breath sampling instrument and the method for sampling breath, belonging to technical field of medical installation. The breath sampling instrument comprises a probe tube which is provided with a gas port and an air outlet. A mouth is arranged on the gas port of the probe tube and a first check valve and a second check valve are arranged in the airflow channel between the gas port and the air outlet. A test sample disconnecting and intercepting device is arranged between the first check valve and the second check valve. By using the breath sampling instrument, the airflow blown out can open the first check valve and then enter the airflow channel when the tester keeps the instrument in mouth to blow or cough, and the test sample disconnecting and intercepting device can separate and keep the fluid phase or the solid phase of the airflow blown out. The gas phase separated opens the second check valve before discharging and then the test sample disconnecting and intercepting device is put out for laboratory test. The invention can not harm or upset the tester and also has the advantages of simple structure and convenient usage, so can be used in quick diagnosis of different diseases.

The invention discloses a carbon dioxide concentration-corrected exhaled gas multi-component detection instrument and detection method. The detection instrument comprises a filter flask, a carrier gas pump, a drying pipe, a sampling gas pump, a sample ring, a first two-phase three-way solenoid valve, a second two-phase three-way solenoid valve, a third two-phase three-way solenoid valve, a chromatographic column and a detection gas chamber, and after communication, a sampling passage, a washing passage and a detection passage are respectively formed. The detection gas chamber is of a cuboid structure and is provided with a PCB tank, a MOS tank, a carbon dioxide sensor tank, a temperature measuring hole, a gas reaction chamber and the like. A sensor can quickly give a response and restore a baseline; after the outputted response is subjected to signal processing and calculation, hydrogen and methane concentrations are obtained and can be corrected according to carbon dioxide concentration, so that sample acquisition constraints are reduced, and the error caused by breath collection and other human factors is reduced. The carbon dioxide concentration-corrected exhaled gas multi-component detection instrument is perfect in functions, small in size, simple and convenient to operate, higher in accuracy, stability and repeatability and friendly in user interaction, and facilitates popularization of large-scale clinical application.

A breath acetone meter is provided. The blood glucose meter includes a receiver comprising a first polymer and a second plurality of layers arranged in an alternating arrangement. The receiver is configured to receive a breath sample from a user. The first plurality of layers and second plurality of layers being configured to interact in response to the level of acetone in the breath sample. The breath acetone meter further including a light source arranged to emit a light onto the receiver. A sensor is arranged to receive the light and output a voltage in response to receiving the light, wherein the voltage is proportional to an amount of acetone in the breath sample.

Methods for detecting a patient disconnecting from a continuous positive airway pressure (CPAP) therapy device are disclosed. A cyclical pressure difference signal is derived based upon measurements from a patient interface pressure sensor and from a source pressure sensor. The pressure difference signal is integrated to generate a resultant integral signal for each respiratory cycle, which is comprised of at least one inspiratory phase and at least one expiratory phase as represented by the corresponding portions of the pressure difference signal. A pressure source of the CPAP therapy device is deactivated in response to a disconnect condition being evaluated from the integral signal. In one embodiment, the disconnect condition is the integral signal exceeding a predefined disconnect threshold. In other, it is a slope value corresponding to a rate of increase of the integral signal exceeding a predefined threshold for a predefined duration.

COVID-19 is a large virus with remarkable resilience, propagation and multiplication features that require complex technologic systems and manners to assure a reasonable protection. A transparent, multiuse face mask with valves and for inhalation of air from a specialized filter placed in a cleaner air space, and an exhalation valve that drives the exhaled air via a tube to a filter bladder placed on wrist and from there to a tube that has the release end near ground, or can be connected to the aspiration tube of the infrastructure, that removes it, preventing recirculation. The general convention that defines the usage method is that the building, buss, and any other enclosure provide clean antiseptic air above and consumer s have to release their exhalations down near floor from where the structure to remove them by a controlled air flow similar to clean rooms.The main condition is that people to place their exhalation exhaust sterilized and placed near ground in order to increase the probability to inhale clean sterile air at the head level. No filter is perfect, and no sterilization unit, therefore the enclosure has to deal with exhaust gas, and remove into the atmosphere safely. The work to keep people inside safe is done by both the enclosure that may provide vacuum lines to collect the exhaled air, and by the people who will use correctly the infrastructure. The system is designed for smart communities for everybody to wear for about 3 weeks when a covid-19 or other virus infection occurs to suppress its multiplication rate, without perturbation in their activity and then returning to normality.

The present invention relates, generally to a method of determining and assessing cytochrome P450 2D6 isoenzyme (CYP2D6)-related metabolic capacity in an individual mammalian subject via a breath assay, by determining the relative amount of 13CO2 exhaled by a the subject upon intravenous or oral administration of a 13C-labeled CYP2D6 substrate compound. The present invention is useful as an in vivo phenotype assay for evaluating CYP2D6-related activity using the metabolite 13CO2 in expired breath and to determine the optimal dosage and timing of administration of CYP2D6 substrate compound.

A breath test and kit for performing the breath test are described for the diagnosis of diabetic indications and monitoring of glycemic control. The breath test utilizes the measurement of expired 13C-labeled CO2 following the ingestion of a 13C-enriched glucose source.

A pressurized flow of breathable gas is delivered to the airway of a subject in accordance with a therapy regimen. The therapy regimen may be designed to maintain oxygenation of the subject. The therapy regimen dictates levels of fraction of inspired oxygen and / or positive end expiratory pressure to maintain a therapeutically beneficial level of oxygenation in a feedback manner. Within the therapy regimen, changes made to fraction of inspired oxygen and / or positive end expiratory pressure automatically and dynamically are constrained by user configured constraints such as the maximum incremental change, amount of time between adjustments, or the maximum rate of change This may provide a level of customization of the automated control of the therapy regime for individual subjects.

The invention provides a fixed mask and belongs to the technical field of masks. The fixed mask comprises a mask shell, a breath assisting system and the like. The breath assisting system is arranged on the mask shell. An air filter is arranged in the breath assisting system. Under the circumstance that normal breath is not influenced, filtered air flows from the outer portion of the mask to the inner portion of the mask in an accelerated mode through the breath assisting system and a user easily breathes the filtered and purified air.

In order to protect the passengers of an airplane against the effects of depressurization of the cabin, breathing masks are fed with oxygen at a rate which is an increasing function of cabin altitude. Oxygen is fed via a constriction and an economizer bag, and an initial fraction only of the gases breathed out is caused to be re-breathed by collecting the initial fraction in a flexible re-breathing bag in communication with the mask. The re-breathing bag has a volume in inflated state which is not less than the total dead volume of the respiratory tract and the mask. A protective apparatus comprises a feed control unit supplying an adjustable flow rate to masks connected to a general pipe via respective economizer bags. A re-breathing bag retards re-breathing and stores only an initial fraction of the gases breathed out on each exhalation.

In the present invention, personal air filtration unit sold as SMARTMOUTH(TM), a trademark for a personal air filtration unit comprised of an outer activated carbon pre-filter and an inner filter for particulate matter available through Tri-Pact Enterprises has been attached to a column of valve connectors which are connected to a tracheostomy tube. The filter has a downwardly dependent exhaust port which allows expired air to flow out of the filtration unit without passing through the filters, thereby helping to prevent mixing of inhaled and exhaled air, and decreasing resistance to exhalation, as well as one-way valves in the form of a flap, on the one hand to prevent exhaled air from entering a dead space between filters, and on the other hand to prevent entering of inhaled air through the exhaust port.

A retractable protective respiratory mask including disposable filters, which protects the respiratory system, covering the nose and mouth during inhalation while breathing in an atmosphere polluted by different agents, such as infectious, virulent, or pathogenic agents, or other toxic substances. The mask also protects non-infected persons from persons infected with a virus, as saliva and sputum expelled when coughing, breathing-out, and / or talking can be deposited inside the mask. The mask can include a collection-container filter, allowing a viral-infected wearer to breathe in a polluted atmosphere, to talk, to cough, to sneeze and / or to deposit saliva and sputum. The mask can be used as any other type of filter mask and / or disposable environmental air mask for industry in general, and also providing protection in rarefied natural atmospheres. The mask can be used as a container or packaging for drugs administered by means of bronchial airways, or as medical or rescue masks.

The invention discloses a portable system (10) for collecting samples in exhaled gas of a subject to detect or determine drug substances in the exhaled gas. The samples are collected for further analysis by mass-spectrography. The portable system comprises a sampling unit (14) and a housing (12) configured to accommodate the sampling unit (14); the sampling unit (14) is suitable for collecting nonvolatile and volatile compounds of at least one drug substance from the exhaled gas of the subject; the housing (12) is provided with at least one inlet (15) and at least one outlet (16), the inlets (15) allow the subject to exhale the gas to the housing (12) and to the sampling unit (14); the outlets (16) allow the exhaled gas to leave.

The monitoring breathalyzer has an alcohol sensor, a non-volatile memory, a processing unit or processor, and a screen. The processing unit determines the accuracy of the breathalyzer using the user's body as a simulator. In monitoring mode, the processing unit receives a BAC% measurement from the alcohol sensor based on the breath sample provided by the user at a sample time and determines a reference point from the BAC% measurement. The sample time is determined based on the user's metabolism rate or based on a time to a predetermined calibration point from a drink start time.

The monitoring breathalyzer has an alcohol sensor, a non-volatile memory, a processing unit or processor, and a screen. The processing unit determines the accuracy of the breathalyzer using the user's body as a simulator. In monitoring mode, the processing unit receives a BAC% measurement from the alcohol sensor based on the breath sample provided by the user at a sample time and determines a reference point from the BAC% measurement. The sample time is determined based on the user's metabolism rate or based on a time to a predetermined calibration point from a drink start time.

A self-calibration exhaled gas analysis device comprises an exhalation control module, a sampling module, a detection module and a control module, wherein the exhalation control module and the sampling module are used for exhausting and sampling exhaled gas of an examinee respectively, and the control module is used for controlling the exhalation control module, the sampling module and the detection module and performing information collection, processing, storage and communication. The sampling module comprises at least two gas chambers for temporarily storing part of the exhaled gas, the gas in the gas chambers is directly measured after the concentration of the gas is quantitatively changed by electrolysis, two gas chambers are connected with the detection module through valves, and the detection module comprises a valve, a sensor, a gas pump and a pipeline and is used for respectively leading the gas in at least two gas chambers into the sensor for measurement.

The invention discloses a novel respirator comprising a mask and a respiration filter device. The mask comprises a base, an outer cover and an inner cover, the edge of the outer cover is clamped on an outer upper platform of the base, the inner cover is clamped on an inner upper platform of the base, and the respiration filter device is clamped between the outer cover and the inner cover. The novel respirator further comprises an inflatable or deflatable hollow air bag which is detachably connected with the base. The shape of the air bag can be adjusted according to facial contours and shapes of nose bridges of different wearers, and adaptation of the respirator and comfort of the wearers are enhanced remarkably; meanwhile, the outer side face of an air bag body is provided with a soft sweat-absorbent pad which can absorb sweat generated by the wearer when using the novel respirator in an environment at high temperature; in addition, the latticed inner cover is directly connected with the base to form a respiratory air cushioning cavity, so that the structure of the respirator is simplified greatly; a one-way air outlet valve component is arranged in the middle of the inner cover, so that exhaled air of human bodies can be discharged out of the respirator to allow the wearers to breathe more smoothly.