183 results about "Dialysis patients" patented technology

Methods and devices for forming an anastomosis between hollow bodies utilizes magnetic force to couple anastomotic securing components and create a fluid-tight connection between the lumens of the hollow bodies. End-to-side, side-to-side and end-to-end anastomoses can be created without using suture or any other type of mechanical fasteners, although any such attachment means may be used in conjunction with the magnetic attachment. The securing components have magnetic, ferromagnetic or electromagnetic properties and may include one or more materials, for example, magnetic and nonmagnetic materials arranged in a laminated structure. The system of anastomotic securing components may be used in many different applications including the treatment of cardiovascular disease, peripheral vascular disease, forming AV shunts for dialysis patients, etc., and may be sized and configured for forming an anastomosis to a specific hollow body, for example, a coronary artery or the aorta.

A method and device for continuously calculating the circumference of a body segment is based on the continuous measurement of the extracellular resistance of the body segment. Also disclosed is a method and device for determining the dry weight of a dialysis patient wherein the time at which the dry weight of the patient has been achieved is identified as the time at which the patient's normalized resistivity as a function of time (ρN(t)) is greater than or equal to a minimum level of normalized resistivity in healthy subjects (ρN,H).

A peritoneal function testing apparatus tests the peritoneal function of a dialysis patient easily and with high accuracy. Standards of four kinetic parameters (CCr, Kt / V, MTACu, and MTACc) available in a definite dialysis guideline are computed in accordance with a relational expression, and a curve showing the relation between MTACu / c and the drained fluid volume is indicated in a graph together with the PET data of the patient which has been prepared separately. Thus, the peritoneal function can be evaluated based on the relative position of the patient's data and the curve showing the standard values in the graph.

A dialysis procedure catheter for accurately facilitating insertion of a needle into a dialysis patient's body. The dialysis procedure catheter includes a tubular member having a bore being disposed therethrough, and also having an enlarged main portion and a branch portion, and further having a needle; and also includes a plug assembly including a plug member being removably disposed in the bore of the needle; and further includes a handle being attached to the enlarged main portion of the tubular member; and also includes a hose having a first end being attached to the branch portion; and further includes a hose clamp for crimping the hose; and also includes a hose connector being attached to a second end of the hose for connecting to a dialysis machine.

The present invention relates to the use of S-alkylisothiouronium derivatives, including S-ethylisothiouronium diethylphosphate, for stabilizing blood pressure in hemodialysis patients. The compositions of the invention are effective in preventing hypotension in hemodialysis patients.

A method and device for continuously calculating the circumference of a body segment is based on the continuous measurement of the extracellular resistance of the body segment. Also disclosed is a method and device for determining the dry weight of a dialysis patient wherein the time at which the dry weight of the patient has been achieved is identified as the time at which the patient's normalized resistivity as a function of time (ρN(t)) is greater than or equal to a minimum level of normalized resistivity in healthy subjects (ρN,H).

This invention provides hemodialysis solutions comprising certain amino acids in certain pre-determined amounts. This invention also provides methods and kits for performing dialysis in a manner which treats or inhibits the onset of malnutrition in the dialysis patient.

A method of detecting a dislodged needle in a hemodialysis procedure includes measuring venous drip pressure of the dialysis machine of a patient undergoing hemodialysis, analyzing the venous drip pressure and deriving intravascular blood pressure at a location of venous needle insertion into the patient, comparing the derived intravascular blood pressure to a standard, repeating the measuring, analyzing and deriving, and comparing steps and, if the intravascular blood pressure is within a specified range of the standard, determining that a needle has been dislodged in the hemodialysis procedure. A method of alerting the patient and medical personnel of a dislodged needle in a hemodialysis procedure includes detecting a drop in intravascular pressure derived from measured venous drip pressure, determining that a needle is dislodged, and alerting medical personnel of the dislodged needle.

A hemodialytic angioacess device for implantation in dialysis patients, comprising an arteriovenous (AV) shunt, anastomotic valves that connect the AV shunt to blood vessels, a valve control system and an integrated surveillance system that measures flow conditions in the blood vessels at the AV shunt, preferably when the valves are closed and the patient is not undergoing dialysis treatment. The flow condition data, which may include data representing the flow rate, pressure, volume and velocity of blood flowing through the vessels, is stored in a memory and transmitted to a health care provider or technician on demand. The data can be used to calculate and monitor important physiological parameters, such as compliance and resistance, for the blood vessels, and help detect and identify dangerous conditions, such as turbulence and stasis, which can contribute to AV shunt failure, vessel injury and other serious complications for the patient.

A method for treating dialysate solutions used in dialysis wherein dialysate is treated in an early part of a dialysis treatment session by external infusion of bicarbonate solution into the dialysate circuit to eliminate the need for bicarbonate requirements in concentrates used for preparation of precursor dialysate (priming) solutions and / or for a solid bicarbonate layer in a sorbent cartridge. Dialysate is treated in a latter part of a dialysis treatment session by introduction of sterile dilution water to reduce sodium concentration in the dialysate. The method provides a more efficient and reduced use of dialysate fluids, electrolytes, sorbent cartridge materials, equipment scale, or any combinations of these, while maintaining purity standards and applicable physiological ranges for bicarbonate, sodium, and other dialysate solution components over the course of a dialysis treatment session.

The invention relates to a portable blood purifying system, which comprises a high throughput dialyzer with an arterial duct, a venous duct, a washing liquid tube and a transfusion tube; the arterial duct is in turn connected in series with an arterial valve, an arterial pressure sensor and a blood pump; the venous duct is in turn connected in series with a venous valve, a venous temperature sensor, a venous bubble detector and a venous pressure sensor, so that an external circulation unit is formed; the washing liquid tube is connected in series with a pre-charging valve and is communicated with a washing liquid container; the transfusion tube is in turn connected in series with a temperature controller, a transfusion tube bubble collector and a transfusion pump, and is communicated with a waste liquid container, so that a waste liquid processing unit is formed; and the system also comprises a transfusion pump, a temperature control device, a transfusion tube, a gating valve and a first transfusion branch and a second transfusion tube branch, so that a transfusion unit is formed. The system is simplified in structure and convenient to carry; and the system is suitable for patients to do short-time dialysis for several times or night dialysis treatment at home as household treatment equipment, so that toxin tolerance of dialysis patients during dialysis period is relieved while medical cost is reduced.

A garment for covering the upper body of a patient undergoing dialysis to keep the patient warm and comfortable during dialysis comprising a jacket made from a warm and soft material for covering the arms and torso of a patient, the jacket having a torso member for covering the torso of the patient, a right sleeve and a left sleeve covering the arms of the patient, at least one of the sleeves having an elongated opening on the inside thereof extending from the torso member to the distal end of the sleeve for providing access to grafts or fistulas on the arm of the patient that may e connected to a dialysis machine and for providing a site for an injection or infusion by a hypodermic needle.

A server device, and related systems and methods for managing dialysis patient information. The patient information includes information relating to stages of data collection including baseline characteristics, eligibility for treatment modalities, and outcomes. A remote terminal is configured for displaying in the remote terminal a first user interface for receiving the patient information for the subject patient. The server is configured to receive from the remote terminal the patient information for the subject patient and store said patient information in a patient record in the memory, and determine, based on medical logic rules, whether the patient information is consistent with the patient record in order to proceed to a next stage of data collection, and if so permitting displaying in the remote terminal a second user interface for receiving patient information relating to the next stage of data collection.

Phosphate depletion, a physiological condition commonly seen in certain patient populations, including alcoholics, malnourished, acutely ill patients, patients receiving parenteral nutrition, patients being re-fed after prolonged fasting, and dialysis patients, requires intravenous supplementation when oral repletion is not feasible. This invention provides a method and pharmaceutical composition for therapeutic administration of pyrophosphate, instead of phosphate, for phosphate or pyrophosphate repletion. During hemodialysis or peritoneal dialysis significant removal of phosphate and pyrophosphate occurs. Pyrophosphate depletion predisposes patients to vascular calcification. This invention further provides a method and pharmaceutical composition for therapeutic administration of pyrophosphate for phosphate or pyrophosphate repletion by addition of pyrophosphate to hemodialysis or peritoneal dialysis solutions.

The present invention provides a garment that includes a neck opening, a front portion, a back portion, and a first and second opposing sleeve portions, and a first, second, third and fourth closable openings. The first and second closable openings extend substantially from a cuff to a shoulder end of the first sleeve portion or the neck opening. The third and fourth closable opening extend substantially from the neck opening to an underarm portion of a first side of the front portion. The garment may also include a pair of pants having a first pant and a second pant each having a front portion and a back portion, and a first and second closable openings extending substantially from an abdomen area to a knee area or ankle area of the front portion of the first and second pants.

A method of detecting a dislodged needle in a hemodialysis procedure includes measuring venous drip pressure of the dialysis machine of a patient undergoing hemodialysis, analyzing the venous drip pressure and deriving intravascular blood pressure at a location of venous needle insertion into the patient, comparing the derived intravascular blood pressure to a standard, repeating the measuring, analyzing and deriving, and comparing steps and, if the intravascular blood pressure is within a specified range of the standard, determining that a needle has been dislodged in the hemodialysis procedure. A method of alerting the patient and medical personnel of a dislodged needle in a hemodialysis procedure includes detecting a drop in intravascular pressure derived from measured venous drip pressure, determining that a needle is dislodged, and alerting medical personnel of the dislodged needle.

A system and method for determining the amount of fluid to be removed from a dialysis patient is disclosed. The system utilizes sensors and a computer. The computer obtains the input parameters from the sensors, along with information added directly by the user, and performs a forward algorithm to determine a recommended change in patient fluid level. As fluid is removed, the effect of the removal on the parameters is detected by the sensors and re-transmitted back to the computer. The computer then performs a backward algorithm to refine the variables used in the forward algorithm and obtain more accurate results. The system and method provide for changing the amount of fluid removed from the patient based on the results of the algorithm and the data received from the sensors.

A method of performing regional citrate anticoagulant dialysis of a patient's blood includes flowing blood from and back to the patient through an extracorporeal circuit including a dialyzer having semi-permeable dialysis membranes and a dialysate chamber surrounding the membranes. The method further includes flowing a dialysate containing calcium and citrate through the dialysate chamber of the dialyzer and introducing citrate into the patient's blood upstream of the dialyzer, whereby the patient's blood is dialyzed. The method can further include predicting the concentration of systemic ionized calcium in the blood of the patient at any point in the dialysis treatment or post-dialysis, such as by a mathematical model. The method can further include statistically correcting the preliminary predicted post-dialysis concentration of systemic ionized calcium in the patient's blood to provide a final predicted post-dialysis systemic ionized calcium concentration. The method can further include statistically correcting the preliminary predicted systemic ionized calcium concentration for any time point during the dialysis treatment to provide a final predicted systemic ionized calcium concentration for that time point.

The invention is directed to a method of determining a dosage of phosphorus binder for a patient undergoing dialysis treatment to achieve a pre-dialysis serum phosphorus concentration within a desired concentration range while achieving a desired net accumulation of calcium. The method includes determining the dosage of phosphorus binder that will achieve pre-dialysis serum phosphorus concentration of the patient that is within the desired concentration range while accounting for the change in the amount of phosphorus removed by the dialysis treatment when the pre-dialysis serum phosphorus concentration of the patient is within the desired concentration range, determining a dialysate calcium concentration that will result in the desired net accumulation of calcium over a complete dialysis cycle, and dialyzing the patient with a dialysate containing a calcium concentration based upon that determination.

A system and method for monitoring the health of dialysis patients with Raman spectroscopy measurements of one or more target analytes is described. The methods include irradiating one or more fluids of interest with light to produce one or more spectrum and detecting the spectrum with a detector. The fluids of interest are preferably those related to dialysis, including hemodialysis and peritoneal dialysis. In a preferred embodiment, the fluids are irradiated with monochromatic light, and one or more Raman spectra are detected as a result of the irradiation. The fluids may be irradiated within the dialysis tubing itself, or removed from the dialysis tubing and irradiated in a separate chamber. The Raman spectra of one or more target analytes of a dialysis patient may be followed over time or compared to one or more reference spectra, thereby providing information on the health of dialysis patients.

Focal and segmental glomerulosclerosis (FSGS) is a kidney disorder of unknown etiology and up to 20% of patients on dialysis have this diagnosis. A large family with hereditary FSGS carries a missense mutation in the TRPC6 gene on chromosome 11q, encoding the ion channel protein Transient Receptor Potential Cation Channel 6. The missense mutation is a P112Q substitution, which occurs in a highly conserved region of the protein, enhances TRPC6-mediated calcium signals in response to agonists such as angiotensin II, and alters the intracellular distribution of TRPC6 protein. Previous work has emphasized the importance of cytoskeletal and structural proteins in proteinuric kidney diseases. Our findings suggest a novel mechanism for glomerular disease pathogenesis.

Provided is a blood diagnosis method and a dialysis machine, using a diagnostic marker which is versatile and which can contribute to the improvements in dialysis treatment and the evaluation of clinical effects,the method including a step for collecting a blood sample from a dialysis patient before and after dialysis; and a step for making a diagnosis regarding the collected blood sample based on a biomarker, wherein the biomarker is identified in advance based on the correlation between the urea clear space (CS) or the cellular membrane clearance (Kc) and profiles of mRNA or proteins.

This invention relates to a method of treating patients who are receiving dialysis treatments. The method includes administering to a patient in need of treatment an effective amount of a thiol or reducible disulfide compound according to the formula set forth in the specification.

The present invention relates to a nutrition preparation for dialysis patients and the preparation comprises the following ingredients: sea cucumber polypeptides, soy protein peptides, whey protein peptides, maltodextrin, fructose, sargassum fusiforme polysaccharides, linseed oil, fish oil, medium chain triglycerides, fructooligosaccharides, oligosaccharides, sodium, potassium, chlorine, calcium, phosphorus, magnesium, iron, zinc, manganese, copper, iodine, selenium, chromium, molybdenum, fluorine, vitamin A, vitamin D3, vitamin E, vitamin K, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, niacin, folic acid, pantothenic acid, biotin and choline. The nutrition preparation method aims at the nutritional and metabolic needs of dialysis patients, uses a reasonable compounding of the sea cucumber polypeptides with a unique pharmacological bioactivity and the sargassum fusiforme polysaccharides, develops a personalized enteral nutrition preparation for dialysis patients, provides balanced nutrition for dialysis patients, and effectively prevents the occurrence of complications.

The invention relates to an on-line relative blood volume detection device and a detection method. The on-line relative blood volume detection device comprises a processor, a timer, an ultrasonic transmitting circuit, an ultrasonic receiving circuit, a zero crossing detection circuit, an ultrasonic transmission probe and an ultrasonic receiving probe, wherein the ultrasonic transmission probe and the ultrasonic receiving probe are arranged on two sides of an artery pot; the processor is a singlechip MSP 430; and the timer specifically is a TDC-GP2 timer. According to the on-line relative blood volume detection device and the detection method, the relative blood volume is worked out accurately and promptly by measuring the travel time of ultrasonic waves in the blood, and the ultrasonic transmission probe and the ultrasonic receiving probe are arranged on two sides of the artery pot for measuring, so that the characteristic of non-invasion can be achieved; moreover, the invention has the characteristics of real-timeness, portability, repeatability and accurate measuring result and can help medical staff to detect the relative blood volume of a dialysis patient in a real-time manner so as to effectively judge the body weight of the dialysis patient.

The invention provides intradialytic parenteral nutrition (IDPN) solutions with low carbohydrate for the treatment of malnutrition in dialysis patients. The IDPN solutions of the invention are particularly advantageous for the treatment of malnutrition in patients who are diabetic or suffer from other glucose management related pathologies or patients who require strict fluid management.

The invention discloses a multi-temperature-regulation massaging device for hemodialysis. The multi-temperature-regulation massaging device for hemodialysis has powerful functions and can be used for effectively heating and keeping heat of a punctured blood vessel of a hemodialysis patient and promoting hemangiectasis, and the puncturing success rate is improved; the punctured blood vessel of the patient can be massaged through simple operation, edema liquid of a punctured part is eliminated and the blood vessel is exposed, so that the puncturing success rate is improved and pains of the patient are alleviated. The hematoma of the punctured part of the patient can also be subjected to cooling treatment and blood capillaries are retracted through cold application, so that partial hyperemia and bleeding are alleviated and the limitation of edema is facilitated. The device is used for carrying out hot application and massaging on the punctured parts including internal fistula and the like of the patient in combination with corresponding medicines, and partial blood circulation can be facilitated; the permeability of tissue cells is improved and the medicines can be easily absorbed; the elimination of the hematoma is accelerated and the absorption of the hematoma is promoted; damaged tissues are stimulated to regenerate and scars are softened; an vascular access of the patient is effectively protected and the living quality of the patient is improved.

The invention discloses a dialysis tube fixing device for a nephrology department. The dialysis tube fixing device for the nephrology department comprises an L-shaped base seat, wherein a gear rail is arranged at the upper end of the L-shaped base seat, a hand type rolling block is arranged on the gear rail, a connection rod with a slide chute is connected with the right side of the rolling block through a rotation disk, a slide block which can slide left and right along the slide chute sleeves the slide chute, and a flexible dialysis tube fixing device is hinged with the side edge of the slide block. According to the dialysis tube fixing device for the nephrology department, the flexible dialysis tube fixing device can be correspondingly adjusted and fixed according to the structure, the length and the diameter of a dialysis tube, a horizontal and vertical regulation moving device can perform arbitrary regulation according to the position of a dialysis patient and the height of a hospital bed, and therefore a user can conveniently use the dialysis tube fixing device for the nephrology department.

In an embodiment, the invention relates to methods, apparatus, computer programs and computer program products for estimating a dry weight of a dialysis patient comprising the steps of determining a first fluid status of the patient between treatment sessions in a first stage, determining a second fluid status of the patient during treatment sessions in a second stage and estimating the dry weight based on the second fluid status.