The invention relates to obstinate arthralgia 
wine used for treating rheumatic and 
rheumatoid arthritis arthralgia and a preparation method thereof and belongs to the field of 
medicine. The obstinate arthralgia 
wine is prepared with, by weight, nidus vespae, bee 
larva, eel blood, garter snake, long-noded 
pit viper, little multibanded krait, 
earthworm, 
centipede, Chinese 
azalea flower, red 
fennel root, four-leaf clover, prepared 
aconite root, prepared kusnezoff 
monkshood root, siegesbeckia 
herb, obscured 
homalomena rhizome, pepper stem, Chinese starjasmine stem, himalayan coralbean 
bark, scarlet 
kadsura root, 
clematis root, pawpaw, Wu Chia Pee, teasel root, cibotii 
rhizome, mulberry 
twig, pine node, wooly datchmanspipe 
herb, 
cassia twig, notopterygium root, pubescent 
angelica root, white peony root, 
geranium herb, silkworm excrement, beautiful sweetgum fruit, Chinese 
taxillus twig, 
drynaria rhizome, red-rooted 
salvia root, common peony root, logwood, ground beeltle, peach kernel, safflower, 
myrrh, zedoary, bidentate 
achyranthes root, 
frankincense, suberect spathololus stem, 
hirudo, Szechuan lovage rhizome, Chinese 
angelica root, hairy asiabell root, 
astragalus, glossy 
privet fruit, prepared 
rehmannia rhizome, sealwort, Chinese wolfberry, licorice and encommia 
bark. The obstinate arthralgia 
wine is rich in 
nutrition and excellent in taste, has 
efficacy of reinforcing qi and blood, tonifying 
liver and kidney, strengthening tendons and bones, dispelling wind and cold and removing dampness, meets 
drinking habits of people and can treat rheumatic arthralgia.