32 results about "Gastrectomy" patented technology

A tool assembly for leak resistant dissection of tissue includes an anvil and a cartridge housing a plurality of staples. The anvil and cartridge have a linear longitudinal portion and a transverse portion positioned distally of the longitudinal portion. The linear longitudinal portion of the cartridge and anvil assemblies is substantially longer than the curved distal portion. In use, when a surgical procedure is performed that requires a plurality of cutting operations, e.g., a gastrectomy procedure, the first cutting operation is performed to form a substantially linear cut line having a curved distal portion that curves towards a specimen side of the organ, e.g., the stomach. In each subsequent cutting operation, the proximal portion of the tool assembly is positioned with the existing cut line such that a termination point of the existing cut line is positioned on the specimen side of the tissue or organ being partially removed.

Methods and devices are provided for performing gastrectomies and gastroplasties. In one embodiment, a method includes gaining access to a stomach of a patient through an opening formed in the patient's abdominal wall and an opening formed in the patient's vaginal wall. Tissue attached to the stomach can be tensioned using a surgical instrument inserted through one of the abdominal and vaginal openings and can be separated from the stomach to free the stomach fundus using a dissecting surgical instrument inserted through another opening, e.g., through one of the abdominal and vaginal openings. The fundus can be at least partially transected using a surgical stapler inserted through one of the abdominal and vaginal openings, thereby forming a stomach “sleeve.” In another embodiment, the method is modified to form another opening in the patient's abdominal wall instead of forming an opening in the vaginal wall.

Devices and methods are provided for ablational treatment of regions of the digestive tract in post-bariatric surgery patients who fail to achieve or maintain the desired weight loss. Bariatric procedures include Roux-en-Y gastric bypass, biliopancreatic diversion, and sleeve gastrectomy. These procedures reconstruct gastrointestinal tract features, creating pouches, stoma, and tubes that restrict and / or divert the digestive flow. Post-surgical dilation of altered structures is common and diminishes their bariatric effectiveness. Ablation of compromised structures can reduce their size and compliance, restoring bariatric effectiveness. Ablation, as provided the invention, starts at the mucosa and penetrates deeper into the gastrointestinal wall in a controlled manner. Control may also be provided by a fractional ablation that ablates some tissue within a target region and leaves a portion substantially unaffected. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.

The invention relates to an orogastric catheter for a longitudinal gastrectomy. The object of the invention is to make available an orogastric catheter that represents an advantageous alternative to the poorly suited catheters used today and that facilitates the work of the surgeon. This novel orogastric catheter is characterized in that this distal part carries a balloon (25) which, in the inflated state, has a shape substantially matching that of the pyloric antrum (4), in such a way as to be able to be lodged in this pyloric antrum (4), the end of the inflated balloon (25) then being in abutment against the pylorus (5), and the distal end of the body of the catheter (20) for its part being in abutment against the pyloric antrum (4), while the part of the body (21) of the catheter (20) arranged above the inflated balloon (25) is wedged against the wall of the lesser curvature (6) of the stomach (1), thus making it possible to determine the position of the start of the closure resection line in the area of the pyloric antrum (4), to define the closure resection line, and to calibrate the pyloric antrum (4) and the gastric sleeve to be preserved.

A compression clip system where compression is used to close a tissue opening, reduce the volume of an organ, ligate dilated blood vessels or compress tissue adjacent to various other types of lesions to induce healing. Compression prevents bleeding and the leakage of body fluids into a body cavity. The opening may be surgery induced as in gastrectomies or formed naturally such as peptic ulcers and hemorrhoids. The system may include a compression clip, a suitable clip applier, a grasper assembly and an endoscope all brought to the compression site via a multi-lumen sleeve.

Devices and methods are provided for ablational treatment of regions of the digestive tract in post-bariatric surgery patients who fail to achieve or maintain the desired weight loss. Bariatric procedures include Roux-en-Y gastric bypass, biliopancreatic diversion, and sleeve gastrectomy. These procedures reconstruct gastrointestinal tract features, creating pouches, stoma, and tubes that restrict and / or divert the digestive flow. Post-surgical dilation of altered structures is common and diminishes their bariatric effectiveness. Ablation of compromised structures can reduce their size and compliance, restoring bariatric effectiveness. Ablation, as provided the invention, starts at the mucosa and penetrates deeper into the gastrointestinal wall in a controlled manner. Control may also be provided by a fractional ablation that ablates some tissue within a target region and leaves a portion substantially unaffected. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.

The present invention provides novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors according to formula (I) that are useful in the treatment or prophylaxis of physiological and / or pathophysiological conditions in mammals, preferably humans, that are mediated by GHS receptors. The present invention further provides GHS receptor antagonists and agonists that can be used for modulation of these receptors and are useful for treating above conditions, in particular growth retardation, cachexia, short-, medium- and / or long term regulation of energy balance; short-, medium- and / or long term regulation (stimulation and / or inhibition) of food intake; adipogenesis, adiposity and / or obesity; body weight gain and / or reduction; diabetes, diabetes type I, diabetes type II, tumor cell proliferation; inflammation, inflammatory effects, gastric postoperative ileus, postoperative ileus and / or gastrectomy (ghrelin replacement therapy).

The invention relates to a TCM prescription capable of replenishing qi to invigorate the spleen, belonging to the TCM field. The technology scheme consists of the following materials in certain ratios: astragalus (30), campanumaea pilosula (12), dried ginger (10), atractylodes rhizome (15), poria (12), dried orangepeel, white cardamom seed (12) and liquorice (9). The medicine has the effect of replenishing spleen and releasing pain. Among the materials, the astragalus, campanumaea pilosula and atractylodes rhizome can replenish spleen and support the healthy energy; the dried ginger, white cardamom seed and dried orangepeel can warm the middle energizer to dispel cold and regulate circulation and release pain; the poria can invigorate spleen to remove dampness and the liquorice can replenish spleen and reconcile all drugs. The combined prescription has the ability of replenishing qi to invigorate the spleen, warming channels and releaving pain. The invention can mainly cure the spleen-yang deficiency patients suffering chronic gastritis, peptic ulcer, chronic enteritis, gastroptosia, malnutrition after gastrectomy, gastrointestinal dysfunction and malabsorption syndromes.

The present invention provides novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors according to formula (I) that are useful in the treatment or prophylaxis of physiological and / or pathophysiological conditions in mammals, preferably humans, that are mediated by GHS receptors. The present invention further provides GHS receptor antagonists and agonists that can be used for modulation of these receptors and are useful for treating above conditions, in particular growth retardation, cachexia, short-, medium- and / or long term regulation of energy balance; short-, medium- and / or long term regulation (stimulation and / or inhibition) of food intake; adipogenesis, adiposity and / or obesity; body weight gain and / or reduction; diabetes, diabetes type I, diabetes type II, tumor cell proliferation; inflammation, inflammatory effects, gastric postoperative ileus, postoperative ileus and / or gastrectomy (ghrelin replacement therapy).

The present invention provides novel triazole derivatives with improved receptor activity and bioavailability properties as ghrelin analogue ligands of growth hormone secretagogue receptors according to formula (I) that are useful in the treatment or prophylaxis of physiological and / or pathophysiological conditions in mammals, preferably humans, that are mediated by GHS receptors. The present invention further provides GHS receptor antagonists and agonists that can be used for modulation of these receptors and are useful for treating above conditions, in particular alcohol disorder, drug abuse, growth retardation, cachexia, short-, medium-, and / or long term regulation of energy balance, short-, medium-, and / or long term regulation (stimulation and / or inhibition) of food intake, intake of rewarding food, adipogenesis, adiposity and / or obesity, body weight gain and / or reduction, diabetes, diabetes type I, diabetes type II, tumor cell proliferation, inflammation, inflammatory effects, gastric postoperative ileus, postoperative ileus and / or gastrectomy (ghrelin replacement therapy).

The invention discloses a gastric tube guiding catheter special for laparoscopic sleeve gastrectomy. The gastric tube guiding catheter is characterized by comprising a pulling piece arranged in a gastric tube guiding catheter body. The thin side wall of the portion near the tail end of the gastric tube guiding catheter body is bent towards the thick side wall of the catheter body when being pulledby the pulling piece. The arrangement of the pulling piece realizes the adjustment of the bending degree of the guiding tail end of the gastric tube guiding catheter body relative to the gastric tubeguiding catheter body. The diameter of the tail end of the guiding catheter body is reduced, and therefore the guiding catheter can pass through the duodenum from the pylorus conveniently, and balloons are arranged at the tail end of the guiding catheter body; the balloons are expanded after being inflated and then can be used for fixing the gastric tube for facilitating surgery operation. An indicator lamp is arranged at the tail end so that the position of the gastric tube can be conveniently determined during surgery. The catheter body is arranged at a gastric terminal part, the balloons are arranged in sections, and different balloons are inflated to guide different parts which are 2 cm, 4 cm and 6 cm away from the pylorus, so that a precise starting point for cutting the stomach is conveniently selected according to different conditions of patients during surgery.

Methods and devices are provided for performing gastrectomies and gastroplasties. In one embodiment, a method includes gaining access to a stomach of a patient through an opening formed in the patient's abdominal wall and an opening formed in the patient's vaginal wall. Tissue attached to the stomach can be tensioned using a surgical instrument inserted through one of the abdominal and vaginal openings and can be separated from the stomach to free the stomach fundus using a dissecting surgical instrument inserted through another opening, e.g., through one of the abdominal and vaginal openings. The fundus can be at least partially transected using a surgical stapler inserted through one of the abdominal and vaginal openings, thereby forming a stomach ''sleeve''. In another embodiment, the method is modified to form another opening in the patient's abdominal wall instead of forming an opening in the vaginal wall.

The present invention discloses a device suitable for a surgical stapler and used for gastric cannula or total gastrectomy.

A gastric band for laparoscopic gastric banding includes a band having a latch portion and a latch element which is fixed to the latch portion when the band is encircled. A filler bag is disposed on the inner circumferential surface of the band. A protecting saddle extends axially from the lateral end of the band and is located corresponding to the filler bag. For gastric band plicaton, the stomach is plicated to form a large gastric pouch and a plicated portion. For laparoscopic sleeve gastrectomy, a part of the stomach is removed to form the stomach to be a small sleeve shape, and the incision location is sewed. The filler bag is covered below the connecting position of the patient's stomach and esophagus by the band, and the protecting saddle is covered onto the plicated portion or incision location to prevent the patient from overeating.

The present invention provides novel triazole derivatives with improved receptor activity and bioavailability properties as ghrelin analogue ligands of growth hormone secretagogue receptors according to formula (I) that are useful in the treatment or prophylaxis of physiological and / or pathophysiological conditions in mammals, preferably humans, that are mediated by GHS receptors. The present invention further provides GHS receptor antagonists and agonists that can be used for modulation of these receptors and are useful for treating above conditions, in particular alcohol disorder, drug abuse, growth retardation, cachexia, short-, medium-, and / or long term regulation of energy balance, short-, medium-, and / or long term regulation (stimulation and / or inhibition) of food intake, intake of rewarding food, adipogenesis, adiposity and / or obesity, body weight gain and / or reduction, diabetes, diabetes type I, diabetes type II, tumor cell proliferation, inflammation, inflammatory effects, gastric postoperative ileus, postoperative ileus and / or gastrectomy (ghrelin replacement therapy).

A safe sleeve gastrectomy reduces gastric volume of a patient's stomach as a weight loss treatment. The safe sleeve gastrectomy utilizes a safety pocket created by a surgeon to increase safety and guide division of the stomach. An instrument tunnel is created to facilitate division of the stomach into a pouch and a sectioned portion. In this manner, over or complete mobilization of the stomach is avoided. The sectioned portion may be lifted for increased visibility to facilitate its mobilization and removal from the patient.

An endoscopic stent for implantation in a patient following sleeve gastrectomy or biliopancreatic diversion with duodenal transposition comprises a stent portion comprising a proximal portion, the proximal portion Defined by a length of about 50 mm to about 200 mm; an enlarged intermediate portion having an enlarged diameter relative to the proximal and distal portions and defined by a length of about 20 mm to about 80 mm; and a distal portion and a polymeric sheath portion joined to and extending distally from said distal end portion of said stent.

The invention discloses a guiding device in gastrectomy, which comprises a flexible traction tube and a flexible curved tube, the curved tube is connected with the traction tube, and a plurality of acoustic holes are arranged on the curved tube along the length direction, and each of the acoustic holes is provided with a plurality of acoustic holes. There are sound-emitting parts, and the connection line between any two sound holes is not parallel to the length direction of the elbow. By pulling the traction tube, the elbow is placed in the stomach, and the stomach is excised according to the shape of the elbow. When the excision position is offset, the elbow is compressed, so that the gas in the elbow flows through the sound hole and triggers the sound-producing part to produce sound. The component emits a sound to alert the operator; in addition, the arrangement of the sound holes can avoid the situation where the stomach wall covers all the sound holes and cannot produce sound. The invention can accurately locate the excision position of the stomach, so that the shape of the remaining gastric bag is more regular and controllable, and the structure is simple and easy to operate.

The invention discloses a gastric tube for laparoscopic partial gastrectomy, and belongs to the technical field of medical instruments. The gastric tube comprises a gastric tube body (1), an elastic part (3) is arranged on the gastric tube body (1), the elastic part (3) is positioned at the periphery of the gastric tube body (1) and a separate cavity (4) is arranged between the elastic part and the gastric tube body (1), a branch tube (5) is also arranged on the gastric tube body (1), the branch tube (5) is communicated with the separate cavity (4), and a one-way valve (6) is arranged on the branch tube (5). When the inner part of the elastic part is not inflated with gas or liquid does not expand, the shape of the gastric tube is similar to that of common thin gastric tubes, and the gastric tube is convenient and safe to insert before operation, does not damage mucosa, and does not need to be taken out after operation; and the gastric tube also plays a supporting tube and a guiding role in the LSG operation, so that excessive cutting of the stomach wall is avoided, the narrow stomach cavity is avoided, the trauma and the pain of a patient are greatly reduced, and the experience feeling of the LSG is obviously improved.

The invention discloses a guiding device in gastrectomy. The guiding device comprises a flexible traction tube and a flexible bent tube, the bent tube is connected with the traction tube, a plurality of sound holes are formed in the bent tube in the length direction, sound production parts are arranged in the sound holes, and the connecting line between any two sound holes is not parallel to the length direction of the bent tube. The bent tube is placed in the stomach by pulling the traction tube, the stomach is cut according to the shape of the bent tube, the bent tube is compressed when the cut position deviates, so that gas in the bent tube flows through the sound holes and triggers the sound production parts, and the sound production parts make a sound to prompt an operator; and in addition, the arrangement of the sound holes can avoid the situation that the stomach wall covers all the sound holes and sound cannot be produced. The guiding device can accurately position the resection position of the stomach, enables the shape of the remaining stomach bag to be more regular and controllable, and is simple in structure and easy to operate.

The invention relates to a linear cutting stitching instrument with a travel indicating device. The linear cutting stitching instrument comprises a fixed clamping plate, a closed clamping plate, a nail pressing seat assembly, a transmission mechanism, a conducting bar, a travel block, a transmission gear and an indicating wheel; one side of the closed clamping plate is provided with a chute; the transmission mechanism comprises a supporting connecting rod, a push knife connecting rod and a band knife rack; the front end of the supporting connecting rod is rotatably connected with the rear end of the push knife connecting rod through a pin shaft capable of sliding forwards and backwards along the chute; the transmission gear and the indicating wheel are rotatably arranged on the upper surface of the closed clamping plate, and the indicating wheel is engaged with the transmission gear; and row teeth engaged with the transmission gear is arranged on the upper surface of the travel block, the conducting bar is spliced with the travel block and arranged on one side of the closed clamping plate, the front lower end of the travel block is supported by a supporting plate spring arranged on the closed clamping plate, and the rear end of the conducting bar is connected with the supporting connecting rod and the push knife connecting rod through the pin shaft. The stitching instrument can be used for facilitating an operation, is suitable for open operation of enterectomy and gastrectomy, and is simple in structure, clear in indication, light and flexible.

The invention relates to a medical appliance, in particular to an integral digestive tract stent. A Y-shaped integral digestive tract stent is mainly characterized by comprising an esophagus tube (1) and Y-shaped intestinal lateral tubes (2) arranged on the esophagus tube (1), wherein an included angle between the two intestinal lateral tubes (2) is 60 degrees to 100 degrees. The Y-shaped integral digestive tract stent solves the problem of digestive tract obstruction caused by stoma focus recurrence of BI-II type anastomosis after the total gastrectomy, and has the advantages that the operation is simple, safe and noninvasive; the eating problem of a patient is solved after one-step implanting; an upper opening of the stent is in a horn opening shape; the stent displacement cannot be easily caused; and two lower openings are in cup opening shapes, and the intestinal mucosa injury cannot be easily caused.

The invention discloses a gastrectomy port position navigation system. The system comprises at least one processor, wherein the at least one processor is used for storing at least one program. When the at least one program is executed by the at least one processor, the at least one processor realizes the following steps: acquiring a historical position of a puncture port, and anatomical structureinformation; acquiring CT data, and generating a body position information model according to the CT data; and determining a position of a candidate puncture port through the body position informationmodel according to the historical position of the puncture port and the anatomical structure information. The system provides a wider view angle and more accurate tactile perception. The operation data are integrated, and the standard and reproducible operation guidance is generated and provided. The empirical operation is replaced, and errors caused by human factors in an operation are reduced.The system is small in data average error, and can also be widely applied to the technical field of medical imaging.

A post gastrectomy anchoring procedure comprises anchoring a sleeve created by a gastrectomy to tissue structure that can better immobilize the sleeve to reduce complications relating to mobility of the sleeve. Namely, the anchoring procedure secures one or more portions of the sleeve to retroperitoneal fat of a patient. One or more bindings attach the sleeve to the retroperitoneal fat.The bindings can be installed to hold the sleeve in a bent or other shape, such as to mimic the natural shape of the patient's stomach and maintain an opening in the angularis of the sleeve.

The present invention provides a probiotic composition for treatment after gastrectomy, the composition of which includes one or more of Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium animal, and Its application as medical preparations, food and health products for post-gastrectomy treatment is provided. The invention also provides a production and preparation method of the probiotic composition. The probiotics selected by the invention have good safety, strong pertinence, no toxic and side effects, low price and can realize industrial production.

A prosthesis that when implanted in the gastrointestinal tract does not impede the normal function of the pyloric sphincter. In some instances, the prosthesis is implanted as part of, or after, a sleeve gastrectomy procedure. The prosthesis includes a stent with an outer surface and a polymeric cover fully covering the outer surface of the stent. The stent includes a proximal stent flange; a proximal stent segment extending distally from the proximal stent flange; and an enlarged stent segment extending distally from the proximal stent segment.

The invention relates to a medical appliance, in particular to an integral digestive tract stent. A Y-shaped integral digestive tract stent is mainly characterized by comprising an esophagus tube (1) and Y-shaped intestinal lateral tubes (2) arranged on the esophagus tube (1), wherein an included angle between the two intestinal lateral tubes (2) is 60 degrees to 100 degrees. The Y-shaped integral digestive tract stent solves the problem of digestive tract obstruction caused by stoma focus recurrence of BI-II type anastomosis after the total gastrectomy, and has the advantages that the operation is simple, safe and noninvasive; the eating problem of a patient is solved after one-step implanting; an upper opening of the stent is in a horn opening shape; the stent displacement cannot be easily caused; and two lower openings are in cup opening shapes, and the intestinal mucosa injury cannot be easily caused.