85 results about "Gastrointestinal mucous membrane" patented technology

The invention relates to a traditional Chinese medicinal powder. The traditional Chinese medicinal powder comprises the following traditional Chinese medicinal herbs in part by weight: 0.5-1 part of medicinal framework material, a medicinal core material which is 1-5 times of the medicinal framework material, and 0-30 parts of compound medicinal material, wherein the medicinal framework material and the compound medicinal material are medicinal materials which contain fiber as a prescription raw material or have stable physical and chemical properties and stability, low moisture absorption, small irritation; and the medicinal core material is the medicinal material which contains volatile, easily-oxidized and unstable traditional Chinese medicinal active components, or is easy to absorb moisture and irritant to oral mucous membrane or gastrointestinal mucous membrane or is poor in taste and color. The traditional Chinese medicinal powder can change the physical properties of medicinal particles and can reduce the loss of easily-oxidized components and the volatility of volatile components; the moisture absorption of the medicinal powder can be improved; the hydrophilicity (wettability) of the medicinal powder can be increased; the mixing uniformity of multiple materials can be improved; the irritation of the medicine to the oral mucous membrane or the gastrointestinal mucous membrane, and the stench of the medicine can be reduced; and the mouthfeel and the color of the medicine can be improved.

The invention relates to a traditional Chinese medicinal composition for treating gastrointestinal tract, in particular to a medicinal composition for treating gastrointestinal tract diseases such as acute and chronic gastritis, enteritis, gastric ulcer, superficial gastritis, gastric acid, gastrectasia, indigestion and the like. The invention also relates to a preparation of the medicinal composition. The traditional Chinese medicinal composition for treating gastrointestinal tract comprises the medicaments in percentage by weight: 10-25 parts of red ginseng, 10-23 parts of poria, 8-20 parts of bighead atractylodes rhizome, 10-25 parts of rhizoma ligustici wallichii, 10-25 parts of rhizoma atractylodis, 10-25 parts of cyperus rotundus, 10-25 parts of medicated leaven, 10-25 parts of gardenia, 10-23 parts of betelnut, 8-20 parts of radix aucklandiae, 5-15 parts of liquorice, 5-8 parts of malt and 10-25 parts of hawthorn. The medicinal composition for treating the gastrointestinal tract is orally taken and has the efficacies of regulating the flow of qi, comforting the stomach, diminishing inflammation, killing pain, repairing gastrointestinal mucosa and ulceration, enhancing gastrointestinal motility, adjusting gastric acid secretion, promoting digestive absorption and the like.

The invention provides itraconazole nanocrystals and a preparation method and application thereof. Acid phase in which itraconazole is dissolved is dropwise added into alkaline phase to over-saturate the itraconazole; the itraconazole molecules are aggregated into amorphous nanocrystalline particles in the presence of a high molecular stabilizer to form a stable structure with itraconazole nanocrystals as a core and the high molecular stabilizer as a shell; and both the solubility and the dissolution rate of the itraconazole nanocrystals are greatly improved compared with those of normal itraconazole nanoparticle suspension. A hydrophilic fragment of the high molecular stabilizer, which is extended into the water, improves the hydrophobicity of the surfaces of the itraconazole nanoparticles, so that the high molecular stabilizer is more easily moistened and dissolved; and the high molecular stabilizer serving as the shell enhances the adhesion between the medicament particles and gastrointestinal mucous membrane, is favorable for improving the bioavailability and reduces the influence of a diet state on the bioavailability. The method of the invention has the advantages of no use of toxic solvent, simple preparation process, low cost and easy industrialization.

The present invention belongs to the field of medicine technology, and is especially oral loratadine disintegrating tablet for treating allergic diseases and its preparation process. The oral loratadine disintegrating tablet includes loratadine as effective medicine component, and excipient mixture comprising disintegrating agent, stuffing, soluble polyol and penetrant. The oral loratadine disintegrating tablet consists of loratadine 20-50 wt%, disintegrating agent 5-15 wt%, stuffing 10-30 wt%, soluble polyol 30-60 wt%, and penetrant 1-5 wt%. The oral loratadine disintegrating tablet, after being disintegrated fast, can cover gastrointestinal mucous membrane widely, and has fast acting, no first pass effect, high bioavailability, and convenient taking.

The invention relates to the technical field of foods and pharmacy, and provides an alimentary canal gel protective agent. The alimentary canal gel protective agent comprises gels and an acid-solublecross-linking agent, wherein the gels are alginate, and the acid-soluble cross-linking agent is a multivalent metal salt or alkali which is insoluble under a neutral condition and soluble under an acidic condition; in addition, the invention further provides a use method and application of the alimentary canal gel protective agent. The alimentary canal gel protective agent and the use method and application thereof have the advantages that a stable gel protective layer is quickly formed on the gastrointestinal mucous membrane surface after the gel protective agent is taken, the absorption of food compositions by the alimentary canal mucous membrane is blocked or delayed through the modes of 'embedding' and 'isolation', particularly the absorption of fat, cholesterol, glucose, heavy metal ions and ethyl alcohol in the food can be reduced, the effects of losing weight, detoxifying emergently, avoiding alcohol, protecting peptic ulcer, reducing blood fat and protecting glucostasis are achieved, no toxic and side effects exist, the gel protective agent can be made into beverages, dissolved medicines and tablets for use, the production is simple and convenient, and the use is convenient.

The invention discloses a lactic acid bacterium composition for protecting the gastrointestinal mucosa. The lactic acid bacterium composition comprises the following components in parts by weight: 5-20 parts of bifidobacterium lactis, 0.5-2 parts of bifidobacterium infantis, 8-25 parts of lactobacillus rhamnosus, 3-20 parts of lactobacillus acidophilus, 3-20 parts of lactobacillus plantarum and 8-25 parts of lactobacillus salivarius. The invention further discloses a processing method for the lactic acid bacterium composition. The processing method comprises the following steps: (1), preparing sclerotia; (2), embedding non-reducing sugar; (3), embedding skimmed milk; and (4), freeze-drying. The lactic acid bacterium composition provided by the invention has the advantages of adjusting gastrointestinal microorganisms to be balanced and protecting the gastrointestinal mucosa.

The invention discloses a montmorillonite suspension for treating acute diarrhea. The montmorillonite suspension is composed of montmorillonite, glucose, a natural polymer suspending agent, sodium benzoate and a proper amount of purified water. The invention also discloses a preparation method of the montmorillonite suspension for treating the acute diarrhea. The method comprises the following steps: putting the montmorillonite, the glucose, the natural polymer suspending agent and the sodium benzoate by proportion into a sealed tank, sufficiently stirring, shaking and uniformly mixing, grinding the mixtures and refining to sieve by a 325-mesh sieve; and adding enough purified water, fully stirring to obtain the suspension, getting a constant volume, homogenizing, sterilizing and packaging. The montmorillonite is processed into the suspension so that the granule is refined, the absorbing force is big, and the protection effect on the gastrointestinal mucous membrane is strong; and the pathogene can be effectively eliminated and the pharmacologic action is rapidly developed.

The invention relates to loratadine lyophilized tablets, and a lyophilization prescription and a technology thereof. The loratadine lyophilized tablets provided by the invention are prepared from a main medicine loratadine and medicinal auxiliary materials. When the tablets are taken, no water is used, and the tablets disintegrate rapidly in mouths. Therefore, the tablets are suitable for patients with swallowing difficulties such as old people and children. Also, the tablets are suitable to be used in trips with water source shortages. The tablets are advantaged in convenient administration, fast absorption, small first-pass effect, and small irritation to gastrointestinal mucous membranes. The market prospect of the tablets is wide. With the lyophilized tablets provided by the invention, side effects of loratadine can be substantially reduced. Also, the invention relates to a preparation method of the loratadine lyophilized tablets.

The present invention discloses iodine replenisher with control released iodine and its preparation process and use. The iodine replenisher is hydrotalcite containing interchangeable iodate radical or iodine ion with iodine content of 0.5-5%. The preparation process includes inserting iodate radical or iodine ion into layers of hydrotalcite; or calcining hydrotalcite at 450-550 deg.c to obtain bimetal oxide and carrying iodate radical or iodine ion to the layered structure of the bimetal oxide. Supporting iodine onto hydrotalcite, which possesses excellent biocompatibility, excellent gastrointestinal mucous membrane affinity, high interlayer interchangeability, high surface activity and great specific surface area, can obtain controlled releasing of iodine and raise utilization of iodine. The control released iodine preparation has low toxicity and high efficiency and may be used as iodine replenisher for human body and animal.

The invention relates to casing smooth muscle collagen preparation method and functional study. In the method, smooth muscles in casing of animals such as sheep and cattle are used as raw materials, and collagen is extracted from the smooth muscles in the casting by processes of washing, acidic and alkaline treatment, heating, stewing, cooling, soaking in alcohol, drying and crushing; and the treated casing smooth muscle collagen is yellowish solid particles. The method has the advantages that: the process flow is simple; the equipment is easy to configure and operate; the energy consumption is low; and the yield is high. The functional study on the casing smooth muscle collagen particles shows that the casing smooth muscle collagen can be developed as a novel assistant medicament for treating gastrointestinal ulcer, diabetes, cancers and other diseases, can serve as a health-care product for promoting digestion and absorption, protecting human gastroenteric mucosa and improving body immune function, can be used as a component of toothpaste for protecting teeth and treating dental ulcer, can be used as a component of cosmetics and has special skin-beautifying, skin-care and anti-wrinkle functions.

The present invention discloses iron replenisher with control released iron and its preparation process and use. The iron replenisher is zeolite containing active iron in 1.5-10 wt%. The preparation process includes the adsorption and ion exchange reaction between bivalent iron salt and zeolite, filtering, drying and crushing to obtain zeolite containing active iron. Supporting iron onto zeolite, which possesses excellent biocompatibility, excellent gastrointestinal mucous membrane affinity, regular pore canal structures and cage spaces, high surface activity and great specific surface area, can obtain controlled releasing of iron and raise utilization of iron. The control released iron preparation may be used as iron replenisher for human body and animal.

The invention discloses an alga-probioticnutritive hair cream applied to cats and a preparation method thereof. Effective components of the nutritive hair cream comprise natural microalgae, active probiotics, schizochytrium algae, lecithin, compound vitamins, mineral substances and the like; the alga-probiotic nutritive hair cream is capable of enhancing immunity of the cats, reducing probabilityof suffering from skin diseases, accelerating hair production, reducing unseasonal hair loss and fundamentally reducing the occurrence of hair ball symptoms; the alga-probiotic nutritive hair cream isalso capable of maintaining health of gastrointestinal mucous membranes of the cats, moistening intestines and stomach, accelerating intestinal tract movement, taking away the hair in the intestinesand stomach, preventing production of hair balls and accelerating excretion of the hair balls; meanwhile, the nutritive hair cream is easily emulsified in vacuum at low temperature, so that the activities of the natural materials in the cream are not damaged; the original flavor is retained; the cream is refreshing and delicious, is high in palatability, is popular with cats, is uniform, fine andsmooth in texture, is not layered, is also capable of improving the appetite of the cats in appearance, and is delicious and highly digestible.

The invention discloses an aspirin slow release tablet which is prepared from the following raw materials in parts by weight: 25-100 parts of aspirin, 15-30 parts of 3% hydroxypropyl methylcellulose alcoholic liquid, 5-10 parts of polyacrylic resin, 2-8 parts of hydroxypropyl methylcellulose and 1-5 parts of talcum powder. The 3% hydroxypropyl methylcellulose alcoholic liquid is prepared from the following raw materials in parts by weight: 2-5 parts of tartaric acid, 8-15 parts of water, 0.8-1.5 parts of polysorbate, 1-3 parts of hydroxypropyl methylcellulose and 25-50 parts of 95% ethanol. Finenesses of aspirin, polyacrylic resin II and hydroxypropyl methylcellulose can pass through an 80-mesh sieve, and viscosity of hydroxypropyl methylcellulose is 55-60Pa.s. The aspirin slow release tablet prepared by the invention is better in uniformity and quality stability, and the release rate of medicine can be more effectively controlled, so that the local medical concentration is reduced, the blood concentration is more stable and sustainable, and toxic and side effects to gastrointestinal mucous membrane are greatly reduced.

The invention belongs to the field of high polymer materials and medical equipment, and particularly relates to a formula and a preparation technology of a submucosal injection sodium hyaluronate solution for an endoscope. According to the formula of the sodium hyaluronate solution, the sodium hyaluronate solution is prepared from sodium hyaluronate, sodium chloride, sodium hydrogen phosphate, sodium dihydrogen phosphate, methylene blue and water for injection. The preparation technology of the sodium hyaluronate solution includes the steps that firstly, sodium chloride is stirred and dissolved in a burdening tank, then sodium hyaluronate is added, temperature is raised to 40 DEG C, and stirring is performed; sodium hydrogen phosphate and sodium dihydrogen phosphate are sequentially added in, and stirring continues; secondly, the pH value of material liquid is measured; the pH value of the material liquid is adjusted to reach 7.0-8.0; thirdly, methylene blue is added and stirred, water is supplemented, and volume is metered; fourthly, filtering is performed through a microfiltration membrane ; fifthly, the mixture is encapsulated in an ampoule or a glass bottle and sterilized with steam at the temperature of 121 DEG C for 15 min, and the submucosal injection sodium hyaluronate solution is obtained. The sodium hyaluronate solution is used for endoscopic submucosal dissection (ESD) and is injected below a gastrointestinal mucous membrane, lesions can be fully swelled, a submucosal liquid cushion is formed, a submucosa and a muscular layer can be effectively separated, and bleeding, perforation and other complications can be reduced while electroexcision is facilitated.

The invention discloses a multifunctional controlled-release anti-inflammatory analgesic paste and preparation method and application thereof. The multifunctional controlled-release anti-inflammatory analgesic paste comprises an adhesive layer and a medicine layer; by use of the electrospinning technology, the macromolecule polymer or the natural high-molecular fiber protein is uniformly mixed with the gold-loaded and magnet-loaded nanometer TiO2 particles, the dispersing agent, the penetration enhancer and the anti-inflammatory analgesic medicine to obtain a mixture, the mixture is placed under the high-voltage electrostatic field to perform spinning so as to obtain the dual-layer nanometer composite film, and then the adhesive is sprayed on the dual-layer nanometer composite film to obtain the multifunctional controlled-release anti-inflammatory analgesic paste. The analgesic paste is used for external application, and capable of effectively avoiding liver first pass effect and the damage on the gastrointestinal mucous membrane by non-steroidal anti-inflammatory drugs (NSAIDs) and other bad effects, and the aims of controlling the release of the medicine by use of an external magnetic field and the near infrared, improving the curative effect of the medicine, and the aim of accelerating the removing of pains in cooperation with the treatment of the infrared therapy lamp can be finally achieved; the multifunctional controlled-release anti-inflammatory analgesic paste has relatively good curative effect on the muscle pains, various arthritis and non-rheumatic inflammation.

The invention discloses a digestive tract mucosa stain, which is an aqueous solution of indigotindisulfonate sodium. The gastrointestinal tract mucosa stain can deposit in the surface of gastrointestinal tract and opening of a glandular tube, so that a distinct contrast is formed between the stained mucosa surface and the unstained part; the unstained bumps among the opening of the glandular tube are easy to wash, and can be repeatedly stained until satisfaction. The mucosa stain is not absorbed by gastrointestinal tract mucosa, and has no side effect.

The invention belongs to the field of feed probiotics preparation, and particularly relates to a compound lactic acid bacterium micro-ecology liquid preparation for healthy dairy cow breeding. The micro-biology liquid preparation is prepared from Lactobacillus plantarum SCI-01 and Lactobacillus plantarum SCI-02 through symbiotic coupling fermentation and covalent cross-linking embedding technology. The compound lactic acid bacterium micro-ecology liquid preparation can be well colonized on a gastrointestinal mucous membrane after being fed to dairy cows, pathogenic bacterium breeding is restrained, the intestinal effective microbial community is improved, the organism immunity is enhanced, the number of somatic cells can be effectively decreased, the recessive mastitis morbidity is decreased, and the milk yield is increased.

The invention discloses a hangover-relieving beverage produced using Camellia chrysantha and Caulis dendrobii as raw materials and a production method thereof. Active ingredients of the hangover-relieving beverage are composed of, by weight, 15-25 parts of Camellia chrysantha leaf or Camellia, 20-40 parts of Pueraria leaf or flower, 15-20 parts of Calendula officinalis, 10-20 parts of Dendrobium nano powder, 10-20 parts of Rhizoma imperatae and 15-30 parts of Flos chrysanthemi. The hangover-relieving beverage contains ingredients like Camellia saponin, Camellia flavone, Dendrobium polysaccharide, dendrobine, various amino acids, trace element selenium, plant protein and vitamins, thereby having efficacy of relieving hangover, clearing heat for detoxification, calming, clearing lung and brain and protecting liver, gallbladder and stomach. The active ingredients of the hangover-relieving beverage can be quickly decomposed in vivo to metabolize alcohol, have functions of promoting liver for detoxification and kidney for excretion, can restore gastrointestinal mucous membrane and normal flora and promote health of a digestive system and have biological functions of activating blood to remove stasis, lowering blood sugar, blood pressure and blood lipid, improving immunity and resisting lipid peroxidation, tumor and senility.

The invention provides a method for preparing angelica dahurica decoction pieces. The method comprises the following steps: (1) grinding a medicinal material such as angelica dahurica into coarse powder; and (2) drying the coarse powder prepared by the step (1), grinding at 12 to 16 DEG C for 20 minutes in a Bailey supermicro pulverizer BFM-100B till a particle size of 300 to 500 meshes. The invention also provides angelica dahurica decoction pieces prepared by the method. The angelica dahurica decoction pieces prepared by the method have the advantages that: after the supermicro medicinal material is ground on a cell level, the surface area is greatly increased, and active ingredients dissolve out quickly; meanwhile, the active ingredients can well contact gastrointestinal mucosa, so theabsorption is easier, the bioactive is retained and medicinal effect is enhanced; and the angelica dahurica super micro powder obtained by the method can ensure good absorption in vivo when the particle size is between 300 and 500 meshes, so the energy consumed in the supermicro grinding process of the angelica dahurica is reduced greatly.

The invention relates to the technical field of health care products, in particular to a composition for preventing and treating hyperuricemia and gout and application thereof. According to the composition for preventing and treating hyperuricemia and gout provided by the invention, the sleep quality can be effectively improved; intestinal endotoxin is synergistically eliminated, and gastrointestinal mucous membrane cell tissues are repaired; uric acid metabolism is promoted through synergistic oxidation resistance; the composition for preventing and treating hyperuricemia and gout is capableof preventing and treating hyperuricemia and ventilation in the aspects of enhancing the immune system, improving the kidney function and the like, has an obvious deacidification effect, and is stablein performance and beneficial to storage.

The invention relates to a multifunctional gastroscope endoscope used for stomach cancer diagnosis. The multifunctional gastroscope endoscope comprises a probe, a connecting tube and a hand grip. Theconnecting tube is arranged at one end of the probe, the hand grip is arranged at one end of the connecting tube, the probe and the hand grip are connected through the connecting tube, water outlet holes are formed around the outer side wall of the probe, a stomach cancer diagnosis device is arranged at the bottom end of the probe, a video probe and an illuminating lamp are arranged between the water outlet holes and the stomach cancer diagnosis device, the illuminating lamp is arranged at the bottom of the video probe, and a microprocessor is arranged in the probe. One cleaning mechanism is designed on the multifunctional gastroscope endoscope so as to solve the problem that when an existing gastroscope endoscope used for stomach cancer diagnosis is used for diagnosing a stomach cancer, foods often gather on the surface of the gastrointestinal mucosa of a patient because of diseases, and as a result great influences are generated when local lesions of the gastrointestinal mucosa are observed and treated under the endoscope.

The present invention discloses the application of natural beta-carotene oil and natural beta-carotene crystal in treating gastrointestinal diseases and protecting gastrointestinal mucous membrane. Animal experiment shows that natural beta-carotene oil, natural beta-carotene crystal, mixture of natural beta-carotene oil and natural beta-carotene crystal, and several monomers of natural beta-carotene have the functions of treating gastric ulcer, duodenal ulcer, gastritis, enteritis, etc. in high curative effect, and the function of protecting gastrointestinal mucous membrane.

The present invention discloses zinc replenisher with control released zinc and its preparation process and use. The zinc replenisher is zeolite containing active zinc in 1.5-10 wt%. The preparation process includes the adsorption and ion exchange reaction between zinc salt and zeolite, filtering, drying and crushing to obtain zeolite containing active zinc. Supporting zinc onto zeolite, which possesses excellent biocompatibility, excellent gastrointestinal mucous membrane affinity, regular pore canal structures and cage spaces, high surface activity and great specific surface area, can obtain controlled releasing of zinc and raise utilization of zinc. The control released zinc preparation may be used as zinc replenisher for human body and animal.

The invention relates to an intestine and stomach resuscitation powder, a composition of traditional Chinese medicine, which solves the problems of single function, long medicine taking period, impossibility of treating the symptoms and root causes of the diseases, unsatisfactory curative effect and low curative rate of the prior traditional Chinese medicines curing intestine and stomach diseases. The powder is prepared according to a formulation as follows by weight proportion: 50-75g of pearl powder, 10-30g of radix ophiopogonis, 5-15g of saffron, 10-30g of bighead atractylodes rhizome, 10-30g of rhizoma corydalis, 50-75g of bletilla tuber, 30-50g of herba patriniae, 5-15g of dried immature fruit of citron orange, 5-20g of fritillary bulb, 50-75g of cuttle bone, 5-15g of cinnabaris and 5-15g of licorice root. The powder can calm the mind and care the stomach, rid the rotten part and discharge the poisonous substances, moisten the internal organs and relieve the stagnation, strengthen body resistance and cure the injured, regulate the immunity and repair the gastrointestinal mucous membrane. The intestine and stomach resuscitation powder also has the advantages of short medicine taking period, possibility of treating both the symptoms and root causes of the diseases, good curative effect and high cure rate which amounts to more than 95%.

The composite mycose nutriment with the health functions of repairing gastrointestinal mucous membrane, resisting tumor, protecting liver and regulating immunity consists of lentinan powder, ash tree flower polysaccharide powder, morel polysaccharide powder, wolfberry fruit polysaccharide, whey protein powder, vinegar, honey, haw portions, barley malt powder, composite vitamins, zinc lactate, calcium carbonate, oligoxylose and water. It has the nutrients and effective components of its ingredients well maintained and has the health functions of resisting chemical mutagensis, resisting virus, regulating blood fat, regulating immunity, resisting platelet aggregation, resisting tumor, etc.

The invention discloses a medicine composition for treating infant spleen deficiency type diarrhea and a preparation method thereof. The medicine composition comprises the following raw medicinal materials: Chinese peashrub root , ventilago leiocarpa, radix pseudostellariae, fructus amomi, radix campanumoeae, polygonum polystachyum, radix glycyrrhizae, jasminum laurifolium, radix salviae miltiorrhizae, fructus forsythia, rhizoma cimicifugae, rhizoma ligustici, vandellia cordifolia, rhizoma atractylodis macrocephalae, potentilla anserina, acanthopanax senticosus, thlaspi arvense, fructus setariae germinatus, dioscorea althaeoides, papaver nudicaule, chinaroot greenbier rhizome, herba lycopi, clove, radix cynanchi paniculati, daimyo oak seeds, coffee senna seeds, rhizoma curcumae, semen euryales, fructus piperis longi, lyonia ovalifolia and copperleaf herb. The medicine composition has the benefits of having the efficacies of strengthening spleen, recuperating stomach, benefiting qi, checking diarrhea and aiding digestion, having the effects of protecting gastrointestinal mucous membrane, enhancing resistance and relieving pain, and having the advantages of taking effect quickly, and being high in efficiency, accurate in curative effect, short in treatment course, free of toxic and side effects, low in price, and the like.

The invention discloses a body-cavity effusion drainage system. The body-cavity effusion drainage system includes a control module, an electric air exhaust pump, a sealed liquid storage tank, an air-pressure detecting module, an effusion catheter and a valve, the electric air exhaust pump is provided with an air suction port which is communicated with the interior of the sealed liquid storage tank through an air catheter, the air-pressure detecting module is arranged in the sealed liquid storage tank, one end of the effusion catheter is communicated with the interior of the sealed liquid storage tank, the valve is arranged on the effusion catheter, the control module includes a controller and a display module which is connected with the controller, the controller is in signal connection with the air-pressure detecting module, is connected with the electric air exhaust pump and controls the electric air exhaust pump, and a battery provides power for the controller. According to the body-cavity effusion drainage system, through the air-pressure detecting module, the air pressure in the sealed liquid storage tank is detected, and information is sent to the controller; through the controller, the electric air exhaust pump is controlled to work, so that the air pressure in the sealed liquid storage tank reaches a preset value, in this way, the pressure is controlled, and the situation is avoided that the gastrointestinal mucous membrane of the human body is damaged when body-cavity effusion drainage is conducted.

The invention discloses a citrus powder composition capable of neutralizing the effect of alcoholic drinks and protecting the liver, and a preparation method of the citrus powder composition, and belongs to the field of food processing. The citrus powder composition capable of neutralizing the effect of alcoholic drinks and protecting the liver is prepared from the following raw materials of citrus powder, radix puerariae powder, carrot powder and traditional Chinese medicine powder, and is prepared through the following steps of preparing the traditional Chinese medicine powder, performing blending, performing steaming, performing drying, performing crushing, performing packaging and the like. The citrus powder composition capable of neutralizing the effect of alcoholic drinks and protecting the liver disclosed by the invention has the following characteristics that compared with a conventional medicine capable of neutralizing the effect of alcoholic drinks, the citrus powder composition capable of neutralizing the effect of alcoholic drinks and protecting the liver can neutralize the effect of alcoholic drinks and can also complement nutrient substances desired by human bodies at the same time, besides, the citrus powder composition capable of neutralizing the effect of alcoholic drinks and protecting the liver is powdery, so that the citrus powder composition capable of neutralizing the effect of alcoholic drinks and protecting the liver is good in solubility, absorption by the human bodies is facilitated, and the efficacy of neutralizing the effect of alcoholic drinks can be faster to achieve; the added traditional Chinese medicine powder has the efficacies of promoting the circulation of qi, promoting diuresis, regulating the function of the stomach, neutralizing the effect of alcoholic drinks, protecting the liver, relieving vomiting, preventing gastrointestinal mucosas from absorbing alcohol, reducing alcohol concentration in blood, alleviating burning sensation of the stomach and the like, so that the gastrointestinal mucosas are protected; and in addition, the whole preparation process is free from additives, safe and free from side effects.

The invention discloses an application to preparation of a gastrointestinal mucosa repair protective agent by using ANKRD22 as a target. The ANKRD22 is used as the target, namely gene knock-out, geneknock-out and reduction or chemicals can reduce expression of an ANKRD22 gene. The invention provides a new target for repair of gastrointestinal mucosa light and moderate injury, namely ANKRD22 geneexpression is restrained, so that stomach tissue LGR5+ stem cells can be amplified, a stomach tissue inflammatory reaction can be alleviated, and the stomach mucosa secretion can be increased.

The invention relates to a peltate leaf perhexiline oral cavity disintegrating tablet which is prepared by the following raw materials in parts by weight: 100-800 peltate leaf dioscorea rhizome extract, 50-300 filling agent, 20-150 disintegrating agent, 1-15 glidant and 1-8 flavoring agent. A preparation method of the peltate leaf perhexiline oral cavity disintegrating tablet comprises the following steps: respectively pulverizing the peltate leaf dioscorea rhizome extract, the filling agent, the disintegrating agent, the glidant and the flavoring agent and screening by a sieve in 50-100 meshes; then mixing all raw material powders; tabletting and preparing a finished product. The peltate leaf perhexiline oral cavity disintegrating tablet has the advantages of rapid disintegration and absorption, good taste, high bioavailability, quite convenient taking and simple and convenient preparation process and more rapid disintegration and dissolution of main medicine components, is more suitable for the emergency treatment of an acute patient, such as an angina patient and enters the gastrointestinal tract to rapidly disperse and widely cover the gastrointestinal mucosal after being disintegrated.