The invention describes a process for determining a biological state through the discovery and analysis of hidden or non-obvious, discriminatory 
biological data patterns. The 
biological data can be from 
health data, clinical data, or from a biological sample, (e.g., a biological sample from a human, e.g., serum, blood, 
saliva, 
plasma, nipple aspirants, synovial fluids, cerebrospinal fluids, sweat, 
urine, fecal matter, 
tears, bronchial lavage, swabbings, needle aspirantas, 
semen, vaginal fluids, pre-ejaculate.), etc. which is analyzed to determine the biological state of the donor. The biological state can be a 
pathologic diagnosis, 
toxicity state, 
efficacy of a 
drug, prognosis of a 
disease, etc. Specifically, the invention concerns processes that discover hidden discriminatory 
biological data patterns (e.g., patterns of 
protein expression in a serum sample that classify the biological state of an organ) that describe biological states.