398 results about "Aminopurine" patented technology

Immunostimulatory compositions described as CpG-like nucleic acids are provided, including nucleic acids having immunostimulatory characteristics of CpG nucleic acid, despite certain substitutions of C, G, or C and G of the CpG dinucleotide. The substitutions can include, among others, exchange of methylated C for C, inosine for G, and ZpY for CpG, where Z is cytosine or dSpacer and Y is inosine, 2-aminopurine, nebularine, or dSpacer. Also provided are methods for inducing an immune response in a subject using the CpG-like nucleic acids. The methods are useful in the treatment of a subject that has or is at risk of developing an infectious disease, allergy, asthma, cancer, anemia, thrombocytopenia, or neutropenia.

The dry-land planting agent refers to a kind of droughtresistance crop's nutrient specific to the growth of the plants. The invention is composed of the following components: AU absorber with super strength, carbamide, potassium dihydrogen phosphate, ammonium dibasic phosphate, calcium nitrate, bitter salt, ammonium molybdate, zinc sulfate, manganese sulfate, boracic acid or borax, ferrous sulphate, fulvic acid potassium, disodium edta, fatty alcohol polyethenoxy ether, 6- benzyl aminopurine, melissyl alcohol, potassium naphthylacetic acid, indolebutyric acid, gibberellin, santobrite, potassium sorbate, ketotriazole, penta azole alcohol., thiram, carbendazim, acid brilliant scarlet, humic acid, bluestone, potassium permanganate, potassium chloride, polyethylene glycol, bentonite or water. The invention is featured by sopping, molding moisture, molding fertilizer, withering resistance, disinsection, sterilization, strengthening the effects of the pesticide, accelerating the burgeon of the plants, increasing roots, innocuity, no pollution and low cost.

Solid forms comprising 4-[9-(tetrahydro-furan-3-yl)-8-(2,4,6-trifluoro-phenylamino)-9H-purin-2-ylamino]-cyclohexan-1-ol, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and / or disorders are disclosed.

Glycosylation of 2,6-diaminopurines or silyl derivatives thereof with a compound of the structureis facilitated by the presence of an optionally silylated 1,3-dicarbonyl compound during glycosylation. Byproducts are minimized, while stereoselectivity may be altered by choice of Lewis acid and other reaction condictions.

The invention discloses a compound composition used for increasing the crop fertilization rate. The compound composition comprises a first component of phethalanilic acid, a second component selected from one or more of brassinolide, 6-benayl aminopurine, compound sodium nitrophenolate, diethyl aminoethyl hexanoate, prohexadione calcium, grain yellowing agents, forchlorfenuron, triacontanol, chlormequat chloride, mepiquat chloride, paclobutrazol, uniconazole, amino-oligosaccharin, humic acid, amino acid, alginic acid and chitosan oligosaccharide, and a third component selected from one or more of boric fertilizer, calcium fertilizer, nitrogen fertilizer, potash fertilizer, phosphatic fertilizer, iron fertilizer, copper fertilizer, magnesium fertilizer, manganese fertilizer, molybdenum fertilizer and silicon fertilizer. The composition can be prepared into an aqueous solution or a soluble solution or wettable powder or water dispersible granules which are allowed to be used for agriculture. The compatibility of all the components is reasonable, the key risks of the phethalanilic acid are lowered while it is ensured that the crop fertilization rate is effectively increased, the nutrition level and stress-resistant capacity of crops are improved, and the increase of production and income of crops is promoted.

The invention relates to a tender stem callus plant regeneration induction culture medium for lonicera caerulea and solves the problems of low plant differentiation rate and high culture medium cost problem of the auxiliary bud or stem tip culture, which is the main tissue culture of lonicera caerulea. The culture medium consists of a large amount of macroelements, microelements and hormone, wherein the hormone consists of 6-benzyl aminopurine at a concentration of 1.0 to 2.0mg / L and indolebutyric acid or naphthylacetic acid at a concentration of 0.05 to 0.2mg. When the LD1 culture medium of the invention is used, the tender stems of lonicera caerulea can be easily induced to form calla, and the induction rates of the calla are all over 90 percent; and the probability of the induction of the calla into plants is high, the plant differentiation rate is up to 50 to 82 percent which is 66.6 to 173.3 percent higher than that of the conventional Murashige-Skoog (MS) culture medium, and the cost is saved by 45.1 percent compared with the reference MS culture medium.

The invention relates to a method for cultivating saussurea involucrate cell, wherein it comprises that using MS basic culture medium wit some NNA (fruitone), 6-BA (6-aminopurine) as the culture medium of callus; inducing the seed of saussurea involucrate into plant; using said plant as expalnt to be differented at special condition, to induce callus; subculturing the callus periodically, to increase the callus; using part of callus to function the seed and collecting the left to be dried as the saussurea involucrate culture; collecting said culture to be dried as the cell culture. The invention can improve the content of effective components.

The invention discloses a quick propagation method for lycoris chinensis. The method comprises the following steps of: taking embryos of the lycoris chinensis, and inoculating the embryos to an induction medium to induce callus; transferring the callus to an MS (Murashige and Skoog) culture medium containing sucrose, naphthyl acetic acid (NAA) and 6-benzyl aminopurine (6-BA) to induce adventitious buds; transferring the adventitious buds to the MS culture medium containing the sucrose, the NAA and the 6-BA to induce bulblets; transferring the expanded bulblets to an MS culture medium containing agar and NAA, and performing induced rooting under illumination; and transferring the rooted bulbs to a transplanting medium of perlite and humus. According to the method disclosed by the invention, the embryos of the lycoris chinensis are used as explants, the explants are induced to generate the callus, then the adventitious buds and the bulblets are induced, and plant regeneration is finally completed, so that a new path is increased for quick propagation of tissue culture of the lycoris chinensis. The method has high propagation coefficient, millions of bulblets can be produced in one year, and an effective path can be provided for quickly propagating seed bulbs; and the test tube plantlets have high differentiation synchronizing degree and good consistency, and the method has high large-scale production development value and good economic prospect.

The invention discloses a modified medium for improving propagation of stems of Dendrobium officinale and a propagation method. The medium comprises MS (Murashige and Skoog) basal medium, cane sugar 20g / l, agar 6g / L, 6-BA (benayl aminopurine) 2mg / l, NAA (alpha-naphthaleneacetic acid) 0.2-0.5mg / l, banana mash 15-20g / l, potato mash 15-20g / l, and common tap water replacing distilled water. The modified MS medium is used to propagate the stems with axillary buds of Dendrobium officinale, alkaloid and polysaccharide content of Dendrobium officinale is evidently increased, and Dendrobium officinale grow normally. By the method, consumption of cane sugar is reduced, the tap water is used to replace the distilled water, and accordingly tissue culture technology for Dendrobium officinale is more convenient, more efficient and resource-saving.

The present invention relates to therapeutic combinations of [2-(6-amino-purin-9 yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester (tenofovir disoproxil fumarate, Viread®) and (2R,5S,cis)-4-amino-5-fluoro-1-(2 hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one (emtricitabine, Emtriva™, (−)-cis FTC) and their physiologically functional derivatives. The combinations may be useful in the treatment of HIV infections, including infections with HIV mutants bearing resistance to nucleoside and / or non-nucleoside inhibitors. The present invention is also concerned with pharmaceutical compositions and formulations of said combinations of tenofovir disoproxil fumarate and emtricitabine, and their physiologically functional derivatives, as well as therapeutic methods of use of those compositions and formulations.

The invention discloses a peanut seed coating additive which consists of the following components in parts by weight: 15-20 parts of Tianda 2116, 3-6 parts of brassinolide, 4-7 parts of gibberellin, 2-5 parts of kinetin, 3-6 parts of 6-benayl aminopurine, 4-7 parts of naphthylacetic acid, 4-6 parts of indoleacetic acid, 3-5 parts of salicylic acid, 2-4 parts of triacontanol, 10-14 parts of amino-oligosaccharin and 2-3 parts of methyl cellulose. According to the optimum mixture ratio of plant growth regulators to physiological activators, the seed germination speed, the germination speed and the seedling growth speed are obviously increased, full, neat and strong seedlings are facilitated, a solid foundation is laid for the final yield of peanuts, the germination of mixed peanut seeds is ahead of time by 2.5-3.8 days, the emergence rate is increased by 4.1-5.4 percent, the content of dry matters in the seedling stage is increased by 13.3-25.0 percent, and the yield of peanut pods is increased by 12.7-21.4 percent.

The invention relates to a plant growth adjusting composition containing triacontanol. The composition comprises active components A and B, wherein the active component A is selected from triacontanol and the active component B is selected from any one of the following compounds: benayl aminopurine, brassinolide, diethyl aminoethyl hexanoate and humic acid. The composition is mainly used for increasing the chlorophyll content of plants, maintaining greenness and preventing aging, accelerating development of the root systems, promoting effective absorption of fertilizers, assisting the inferior parts of the plants to grow well, enhancing absorption of water and fertilizers by the plant and adjusting balance of water in the plants, so that the drought resistance and cold resistance of the plants are improved.

The invention relates to a method for accelerating germination of carya illinoensis seeds in late winter and early spring, belonging to the technical field of fruit tree and forest cultivation. The method comprises the steps of: 1) collecting seeds and removing impurities; 2) soaking the seeds in 3% of potassium permanganate solution for 30min for sterilization; 3) soaking the seeds in cold water for 5 days; 4) laminating and storing in sand at low temperature; 5) soaking the seeds by hormone: soaking the seeds in 500mg / L of GA3 (gibberellic acid), 50mg / L of IBA (indolebutyric acid) and 50mg / L of 6-BA (6-benzyl aminopurine) for 24 hours; 6) treating in a high-voltage electrostatic field (HVEF) with intensity of 30KV / cm for 1 hour; and 7) accelerating germination and sowing, and counting the germination rate after a month, wherein the germination rate is above 96%. By using the method, the sowing of the seeds is brought forward by more than 2 months and significance is brought to the seedling culture of the carya illinoensis.

The invention discloses a method for regenerating and planting medicinal anoectochilus roxburghii with the stem removed but the root left, which has the key point of regeneration with the root left and stem removed. First, strong tissue culture seedling are elected and then transmitted to be planted in a mixed substrate consisting of soil, coarse sand and wood dust after plantlet hardening and watered with a mixed liquid of root agent and carbendazim wettable powder. Field management, fertilization and disease preventing and treating are required to be respected during the growth period of the anoectochilus roxburghii. By applying the method of regeneration with the stem removed and the stem left, the anoectochilus roxburghii stems on the ground are harvested but a stem node at each stem is left before the bolting and blossom of the anoectochilus roxburghii. After harvesting, the remained plant is sprayed with a mixed liquid of 6-benzyl aminopurine and carbendazim wettable powder. The method aims at solving the problem of narrow availability of the anoectochilus roxburghii seedling and easily sprouting of the stem node thereof and adopts the production method of regeneration with the stem removed and the stem left, thereby improving the seedling use ratio, guaranteeing the product supply and realizing continuous production. Meanwhile, the complete retaining of the root system creates the good condition for the quick growth of new sprouts and therefore, the regeneration method of the invention has comparatively high production efficiency and good economic benefit.

The invention relates to a plant growth regulation composition containing plant activator protein. The composition comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is selected from the plant activator protein; the active ingredient B is selected from any one of compounds as follows: benzyl aminopurine, brassinolide, indoleacetic acid, harpin protein and gibberellic acid. The composition is mainly used for increasing the plant chlorophyll content, keeping plants green, preventing plant senescence, promoting root development and effective absorption of crops on fertilizers, assisting in good growth of weak parts of the crops, enhancing the absorption of the plants on water and the fertilizers and regulating the balance of the water in the plants so as to improve the drought resistance and the cold resistance of the plants.

The invention discloses a tissue culture and propagation method and inductive culture mediums for Chongzuo camellia nitidissima. According to the method, the improved MS, 6-benayl aminopurine (6-BA) and 3-indoleacetic acid (IAA) are used as an inductive culture medium for the cluster buds of Chongzuo camellia nitidissima; and the combination of the two growth hormones can be used for activating acting enzymes in the body cells of Chongzuo camellia nitidissima, and promoting the germination and the growth of the explants of Chongzuo camellia nitidissima in a proper concentration and a weakly acidic environment; the thick and strong cluster buds can be formed after the culturing for 55 days, and the propagation rate is increased by 20 times. According to the method disclosed by the invention, 1 / 2 improved MS and indolebutyric acid (IBA) or 1 / 2 improved MS and napthaleneacetic acid (NAA) are further used as an inductive culture medium for rooting, and capable of effectively promoting the single seedlings of Chongzuo camellia nitidissima to root to form new plants. Via the tissue culture and propagation method applying the three inductive culture mediums for Chongzuo camellia nitidissima, Chongzuo camellia nitidissima can be rapidly and effectively propagated, thus solving the problems that wild resources are diminished gradually and the natural propagation rate of Chongzuo camellia nitidissima is low, and effectively protecting the precious plant genetic resource which is rare in the world.

The invention relates to the field of flower propagation methods, in particular to the field of corm flower propagation methods. A thin layer culture method of tulips comprises the following steps of: longitudinally or transversely cutting tulip scales into thin layers of 0.1-5mm, and laying the thin layers on a culture medium; and inducing and proliferating the culture medium into an MS (Murashige and Skoog) culture medium, wherein 1.0-2.0mg of 6-BA (Benzyl Aminopurine), 0.1-1.0mg of NAA (Naphthyl Acetic Acid), 1.0-4.0mg of 2, 4-D (2,4-Dichlorophenoxyacetic acid), 20g of cane sugar and 6g of agaragar are added to the MS culture medium per L, the culture condition is that the temperature is 23+ / - 2 DEG C, the illumination intensity is 1,500-2,000Lx, and the illumination time is for 16h / d. The thin layer culture method of the tulips has the advantages and active effects: the tissue culture bulb inductivity reaches 100%, induced tissue culture seedlings grow vigorously, the source of the tissue culture seedlings is not limited by seasons, and the tissue culture scales are the better source of thin layer culture materials. Cutting modes cause different inductions on bulbs, and the differentiation rate and the bulb induction number of the scales which are transversely cut are higher than those of the scales which are longitudinally cut.

Provided herein are Aminopurine Compounds having the following structure: (I) wherein R<1 >, R<2> and and R<3> are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.

The invention discloses a cherry rootstock tissue culture medium, which is prepared from 2 to 60 ml / L of optimized MS base mother solution, 2545 g / L of sucrose, 6.5 to 7.0 g / L of agar, 0.4 to 0.6 mg / L of 6-Benzylaminopurine, 0.1 to 0.3 mg / L of indolebutyric acid, 0.061 to 0.067 mg / L of VC, 0.05 to1.00 mg / L of indoleacetic acid and 1000 to1200 mg / L of active carbon; the culture medium is specifically applied to the growth and cultivation of the bud of the dwarf cherry rootstock, the cultivation of the strong stock and the cultivation of the induced root; the proliferation and root-growing effect is excellent so that the root-growing rate of the dwarf cherry rootstock can reach 95% to 98%; the root is rough and tidy; the culture bud is healthy; the leaf is green, therefore, the labor and material are effectively saved; the survival rate of the transplant can reach 95%, and the foundation is established for the large-scale production. The tissue culture medium method disclosed by the invention is simple and easy, thereby simplifying the program, improving the efficiency, and reducing the cost. In the invention, the problems of brown stain and vitrification in the culture process of tissue culture medium can be solved; and therefore, the invention can be applied to the fast reproduction of the Gisela sweet dwarf cherry rootstock in the large-scale production.

The invention discloses a method which can control the blooming and the propagation of the spring dendrobium. Firstly, a plant growth regulator which is favorable for the growth of the side bud of the plant is selected, and is sprayed on the spring dendrobium plants by proper consistence and proper use method to accelerate the axillary bud to grow. When spraying the plant growth regulator, low temperature of 8-13 DEG C is matched; manure water, other circumstance condition, spray consistence and spray time are controlled, and then the axillary bud is induced to grow into a flower bud and then a flower. Or proper temperature and manure water are matched, and the sxillary bud is induced to grow into a high bud for propagation. The selected plant growth regulator is 6 benzyl aminopurine, the spray consistence is 100ppm to 500ppm; the spray method is leaf surface spray or irrigation. The invention can cause the gemma of the axillary bud of the spring dendrobium to sprout tidily, and can ensure the florescence to be unified, as well as can ensure the propagation efficiency to be high.

The invention discloses a method for simultaneously determining multiple plant growth regulators in exported vegetables. The method comprises the following steps: extraction, purification, concentration, ultrahigh-performance liquid chromatography-triple quadrupole / composite linear ion hydrazine mass spectrometer (UHPLC-QTRAP) determination and the like. The method can simultaneously determine the 17 plant growth regulators, including gibberellin, indolyl-3-butyric acid, p-chlorophenoxyacetic acid, abamectin, diethyl aminoethyl hexanoate, atrazine, simazine, 6-benzyl aminopurine, 2,4-dichlorphenoxyacetic acid, forchlorfenuron, mepiquat chloride, chlormequat chloride, paclobutrazol, uniconazole, abscisic acid, thidiazuron and p-fluorophenoxyacetic acid. The method disclosed by the invention has the advantages of simple steps, short time consumption, high accuracy and high precision.

Provided herein are Aminopurine Compounds having the following structure: (I) wherein R<1 >, R<2> and and R<3> are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.

The invention discloses a rapid propagation method of dendrobium officinale. The rapid propagation mehod comprises the following steps: washing and sterilizing an explant; inoculating the explant in an adventitious bud induction medium which comprises an MS basic culture medium, 2.0mg / L-3.0mg / L of 6-BA (6-Benayl Aminopurine) and 0.2mg / L of NAA (N-Acetyl Aspartate); inoculating an adventitious bud stem in a protocorm induction medium which comprises a B5 basic culture medium, 2.0mg / L of the NAA, 0.2mg / L of the 6-BA and 0.5mg / L-2.0mg / L of KT; inoculating a protocorm in a protocorm propagation culture medium which comprises 1 / 2 of the MS basic culture medium in the step 1, 50g / L of coconut juice; transferring the protocorm in a differential medium which comprises 1 / 2 of the MS basic culture medium in the step 1, 0.2mg / L of the NAA, 80g / L-100g / L of a potato extract; inoculating differentiated seedlings in a seedling and root growing culture medium which comprises 1 / 2 of the MS basic culture medium in the step 1 and 100g / L-150g / L of a banana extract. The rapid propagation method disclosed by the invention has the effects of increasing the survival rate of tissue cultured seedlings of the dendrobium officinale and by using the method, plants of the dendrobium officinale grow healthily and strongly.

The invention sets forth parallel-stranded hairpins and parallel-stranded hairpins carrying a single strand target, the parallel-stranded hairpins containing 8-aminopurine residues and are able to bind a target molecule of interest due to specificity in the two-dimensional and three-dimensional structures of the parallel-stranded hairpins and parallel-stranded hairpins carrying a single strand target. The invention also relates to creation of a library of parallel-stranded hairpins and associated triplexes for use as aptamers, as well as methods of synthesis of parallel-stranded hairpins and use of the structures of the invention to detect and eliminate molecules of interest.

The invention relates to a plant growth regulating composition containing jasmonic acid and methyl jasmonate. The plant growth regulating composition contains an active component A and an active component B, wherein the active component A is jasmonic acid or methyl jasmonate, and the active component B is any one selected from a group consisting of benzyl aminopurine, forchlorfenuron, ethephon, tetramethyl glutarate, mepiquat chloride and choline chloride. The plant growth regulating composition is mainly used for improving enzyme activity, promoting seed germination, enhancing germination capacity and photosynthetic intensity, increasing the content of chlorophyll, maintaining greenness, preventing ageing, promoting development of roots and effective fertilizer absorption of crops, assisting the inferior part of a crop in good growth, enhancing absorption of water and fertilizer by plants and adjusting the balance of moisture in plants so as to improve drought resistance and cold resistance of plants; and the plant growth regulating composition can improve immunity, disease and insect resistance and crop quality and increase yield and income.

A process for preparing the injection of carnosine features that the chitosan and oligose are used for adsorbing the modified protein and fat to improve the purity of product, and the 6-aminopurine phosphate is used as the protector for increasing the sterilizing temp and time to 121 deg.C and 30 min, so having no bacterial pollution.

A compound or a pharmaceutically acceptable salt or composition thereof for the treatment of a host infected with or exposed to a virus of the Paramyxoviridae or Orthomyxoviridae family, or other disorders, in particular respiratory syncytial virus, more fully described herein.

The invention belongs to the production technical field of vegetables, and in particular relates to a quick production method of strontium-enriched bean sprouts, which comprises the steps that: plump mung beans or soybeans are selected and are soaked in the strontium-enriched water with the temperature of 10 DEG C to 36 DEG C for 6 to 15 hours after being washed; after the soaking water is filtered, the mung beans or the soybeans are cultured for 48h to 96h under the condition that the temperature is 20 DEG C to 36 DEG C, the relative humidity is 90 to 95 percent, the material paving density is 0.05g / cm2 to 0.2g / cm2; and during the sprouting process, strontium-enriched nutrient fluid is sprayed, and the interval spraying time is not more than 4 hours. The strontium-enriched water is takenfrom natural strontium-enriched mineral water or the strontium-enriched water solution which is artificially prepared, the strontium content which is calculated through the strontium element is 0.02pm to 0.40ppm, content of gibberellin in additional ingredients is 10mg / L to 300mg / L, content of 6-benzyl aminopurine is 2mg / L to 20mg / L, content of potassium nitrate is 100mg / L to 1500mg / L, content ofcalcium nitrate is 100mg / L to 1500mg / L and content of bitter salt is 100mg / L to 1500mg / L; and the strontium content in the cultured bean sprouts is 0.5ppm to 2.5ppm.

The invention discloses an initial culture medium special for preventing brown stain of strawberries, which is prepared by taking an MS culture medium containing 0.2-0.5 mg / L of 6-benayl aminopurine (BA) and 0.1-0.2 mg / L of naphthylacetic acid (NAA) as a basic culture medium and adding vitamin C (VC) with the concentration of 5-15 mg / L and brassinolide (BR) with the concentration of 0.001-0.5 mg / L, wherein the brown stain rate in the initial strawberry tissue culture process can be greatly reduced; and the germination rate can be increased. The invention further discloses a method for producing tissue culture strawberry seedlings by culturing strawberry stem tip tissues through the culture medium, which comprises the steps of taking strawberry seedlings, sterilizing, inoculating, initially culturing, sub-culturing, acclimating, carrying out virus identification, breeding in a net yarn greenhouse and the like. According to the invention, the brown stain phenomenon in the initial strawberry culture can be effectively prevented; the anti-oxidant condition in the initially cultured strawberry tissues is effectively improved; and the germination rate is increased to be above 70% from 40-60%.