220 results about "Pachymaran" patented technology

The invention discloses a carboxymethyl pachyman (CMP) with high-degree of substitution and making method and application, which is characterized by the following: adopting water or water alcohol solution as dielectric; proceeding substitution reaction for pachyman, chloroacetic acid and fitful excessive sodium hydroxide to obtain CMP without vibrating technique and equipment; improving CMP D / S and solubility to reach injection need.

The invention provides a comprehensive nutritional and semi-digested formulated food for special medical use, and a preparation method thereof. Every 100 g of the comprehensive nutritional and semi-digested formulated food for special medical use comprises 5-15 g of hydrolyzed whey protein, 3-8 g of egg white protein, 1-4 g of soy isolate protein, 1-4 g of concentrated whey protein, 0.5-2 g of sodium caseinate, 37-60 g of carbohydrate with a low GI value, 1-4 g of fructose oligosaccharide, 0.005-0.05 g of carboxymethyl pachymaran, 15-22 g of vegetable oil powder, 4-10 g of a medium-chain fatty acid, 3-8 g of a mineral premix and 0.2-1.4 g of a vitamin premix. A finished product is prepared by mixing the above components uniformly. With a synergistic effect of the above components, partial digestion functions of a patient after operation can be taken fully used to keep, maintain and promote comprehensive restoration of the digestion functions of the patient; an immune function can be regulated; and body disease-resistant ability can be enhanced, thereby influencing development and conversion of the disease.

The invention discloses healthcare yellow wine with poria cocos and a preparation method of the healthcare yellow wine with the poria cocos. The healthcare yellow wine with the poria cocos is made from raw materials mainly including sticky rice, the poria cocos, Chinese yam, medlar, fructus crataegi and red dates. The preparation method includes: cleaning the sticky rice and soaking the same till rice grains are soft; smashing and evenly blending the poria cocos, the Chinese yam, the medlar, the fructus crataegi and the red dates with the soaked sticky rice prior to cooking, spreading the cooked sticky rice blended with the poria cocos, the Chinese yam, the medlar, the fructus crataegi and the red dates prior to adding in Angel sweet distiller's yeast for saccharification, further adding in proper brewing water and activated yellow wine yeast, and subjecting fermentation liquor to squeezing, filtering, wine decocting and ageing after primary fermentation and secondary low-temperature fermentation. The healthcare yellow wine with the poria cocos is rich in functional components such as pachymaran and the like and does not cause dizziness due to low alcohol content, and has the healthcare functions of being anti-fatigue and anti-aging, calming and soothing the nerves and the like.

The invention discloses a Poria cocos extract. The content of pachymaran and Poria cocos triterpene in the Poria cocos extract is 55-95wt%. A preparation method of Poria cocos extract comprises the following steps: crushing Poria cocos, sieving, and proportionally mixing with ethanol; carrying out microwave extraction in a microwave extraction device; and filtering through a micro-porous filtering film, abandoning filter residues, and mixing the above filtrates to obtain a liquid Poria cocos extract, or concentrating the filtrates and drying to obtain a solid Poria cocos extract. The invention also discloses the preparation method of the Poria cocos extract. The method has the advantages of mild extraction conditions, fast speed, small application amount of a solvent, good selectivity, simple operation and the like. The Poria cocos extract prepared in the invention is from a traditional Chinese medicine, has the advantages of remarkable effects and high safety factor, has bacterium preventing, inflammation eliminating, high moisturizing, oil secretion regulating, immunity enhancing, oxidation resisting, aging resisting and allergy resisting effects, can be used in health foods and beverages, pharmaceuticals and cosmetics, and enlarges the application value of Poria cocos.

The invention provides a pachyman preparation, wherein the dosage forms include oral liquid, capsule, pill, tablet, pelletized granule, dispersible tablet, effervescent tablet, and injection, the main composition is pachyman (C6H1206)n no less than 90% calculated by glucose. The preparing process for the pachyman is also disclosed.

The invention discloses an extraction method of pachymaran, comprising the following steps of: performing ultrafine grinding on a tuckahoe raw material to obtain tuckahoe powder; performing enzymatic extraction to obtain filtrate; concentrating the filtrate until the specific gravity is 1.05-1.10, then filtering, and drying the filtrate to obtain pachymaran. The extraction method of pachymaran disclosed by the invention has easy-to-control process conditions, can improve the yield to 25%, and has the advantages of mild reaction conditions, no toxic and side effect of reaction products and the like.

The invention provides a preparation method of carboxymethyl pachyman and a novel application of the carboxymethyl pachyman. According to the method, in the process of carrying out carboxymethylation modification on pachymaran, components and ratios of a reaction medium are changed, the reaction temperature is regulated and a catalyst process is adopted, so that the carboxymethylation efficiency of the pachymaran is remarkably improved, the utilization rate of the raw and auxiliary materials is increased, and the cost is saved. Meanwhile, by virtue of the novel application of the carboxymethyl pachyman prepared by the method to preparation of immunopotentiators of livestock and poultry, the immunity to pathogenic microorganisms of the livestock and the poultry can be remarkably enhanced, and the immune efficacy of vaccines can be improved; by virtue of the novel application of the arboxymethyl pachyman prepared by the method to feed additives, the meat performance of the livestock and the poultry can be effectively improved.

The invention discloses a novel tuckahoe strain (china center for type culture collection (CCTCC) M2011072) and bag-material efficient cultivation technology. The novel tuckahoe stain is applied to cultivation by adopting the bag-material efficient cultivation technology. The novel tuckahoe stain is mainly characterized in that 1) a mycelium is strong, white, obvious in clamp connection; and hypha is spread quickly in a cultivation process; 2) the tuckahoe fruits earlier, the fruit body is even and strong, the color of pulp is white or light yellow, and the skin of tuckahoe is thin and presents purplish red color; 3)the novel tuckahoe strain has the advantages of being stable inheritable characteristics, strong in anti-bacteria infection capacity, high in biological efficiency and yield, good in quality and the like; and 4) the novel tuckahoe strain remarkably improves content of effective components of amino acid, pachymaran and the like in the tuckahoe.

The invention relates to the food processing field and discloses a preparation method of braised meat with delicious taste and rich nutrition. In the invention, the western meat product production technology is combined under a condition that the traditional braised meat production and processing principle is used, the injection seasoning technology, the vacuum massage technology, the vacuum frying technology and the microwave sterilization technology are integrated to form a production process of cooked braised meat foods; pork, long pepper oil, medlar oil, pachymaran, spice and pickled vegetable are adopted as raw materials, and the braised meat has a health-care function to a certain extent. The method in the invention solves the problems that the traditional braised meat can not be stored for a long time at normal temperature, has poor taste stability and can not be produced in a large-scale industrial manner, and the method for producing a microwaveable functionality braised meatwith delicious taste industrially is provided and can effectively maintain the nutrient contents, and the braised meat has the health-care function to a certain extent, the shelf life of the braised meat can be prolonged to be more than one year, the raw materials are quantified to be convenient for product quality control, and the preparation method has an application prospect of large-scale industrial production.

The invention relates to an oral probiotic composition, which contains Streptococcus salivarius K12, and one or more of the Chinese herb extract effective ingredients eugenol, tea polyphenol, glycyrrhizic acid, menthol, radix scrophulariae total glycoside, hericium erinaceus polysaccharide, Pachymaran, a dark plum water extract, and pueraria isoflavone. The composition can adjust oral flora balance, clean the oral cavity and improve oral air, and also has the efficacy of diminishing inflammation and relieving sore swollen throat.

The invention discloses a compound immunopotentiator for sea cucumber and a preparation method thereof, aims to solve the technical problems that antibiotic is used for preventing and controlling diseases of sea cucumber and the utilization rate of the conventional Chinese herbal medicine fished product is low, and provides a compound immunopotentiator for sea cucumber. In order to solve the problems, the technical scheme is that: the compound immunopotentiator for sea cucumber comprises polysaccharide microcapsules at least consisting of a core material and a wall material, wherein the wall material comprises sodium alginate and chitosan; the weight ratio of the core material to the sodium alginate to the chitosan is 1:(2.8-3.5):(1-2); and the core material is at least one of an astragalus polysaccharide extract and a pachymaran extract. Experiments prove that the immunopotentiator effectively improves the immunoprotection capacity of the sea cucumber, and is safe and high-efficiency.

The invention relates to a pachymaran extracting method. The method comprises the steps of 1, smashing poria cocos and then adding the smashed poria cocos to 4-6 times water to be expanded, and adding saccharomycetes and lactic acid bacteria based on 1-5% (w / w) according to the ratio of 1:2 for fermentation, wherein fermentation temperature is 28-31 DEG C, PH is 3.1-4.0 and time is 12-16 h; 2, evenly mixing a fermentation broth, and adding a complex enzyme preparation which contains cellulose, hemicellulase, amylase and pectinase based on 1.2-2.5% (w / w), wherein reaction temperature is 36-42 DEG C, PH is 3.5-4.2, and time is 10-12 h; 3, conducting reactant alcohol precipitation with alcohol, adding alcohol to enable the alcohol content of a reactant to reach 80% (w / w), and conducting spray-drying on an alcohol precipitation substance to obtain about 70.2% water-soluble pachymaran. The method has the advantages that extraction technique is simple, extraction time is shortened, extraction conditions are mild, the obtained pachymaran is high in content and biological activity, and the effect is remarkable compared with the existing extraction technique.

The invention relates to a new technology for preparing poria polysaccharide extract through membrane separation and purification technology. The technology comprises the following steps: (1) grinding and sieving poria powder into crude powder with 20 meshes, and then adding five to ten times of deionized water to obtain feed liquor; (2) filtering the feed liquor obtained in the step (1) through a centrifugal machine; (3) filtering the filtrate obtained in the step (2) through a micro-filtering membrane PP cotton; (4) further filtering the filtrate through the polysulfone hollow fiber type ultrafiltration film with nominal molecular weight cutoff of 10000 dalton; (5) drying the filtrate obtained in the step (4) in a vacuum freeze-drying manner; (6) carrying out anti-oxidization and anti-aging research to the poria polysaccharide by taking a drosophila as an animal model; (7) carrying out hypoglycemic action research by adopting an in-vitro alpha-glucosidase inhibition model through the poria polysaccharide prepared in the step (5). The new technology is simple to operate, and capable of greatly increasing the purity and efficiency of polysaccharide.

The invention provides a preparation method and new application of carboxymethylpachyan. In the process of carrying out carboxymethylation modification of polysaccharides, by changing the composition and proportion of the reaction medium, adjusting the reaction temperature, and using catalyst technology, the efficiency of carboxymethylation of polysaccharides is significantly improved, and the ratio of raw and auxiliary materials is improved. Utilization rate saves cost. At the same time, the new application of carboxymethyl pachyrhiza provided by the present invention in the preparation of livestock and poultry immune enhancers can significantly improve the immunity of livestock and poultry when dealing with pathogenic microorganisms, and improve the immune efficacy of vaccines; The new application of the provided carboxymethylpachyran as a feed additive can effectively improve the meat production performance of livestock and poultry.

The invention provides a pachymaran injection and a preparation method thereof. The injection comprises carboxymethyl pachymaran, water for injection, benzyl alcohol and Tween 80. Each milliliter of the injection comprises 2 mg of carboxymethyl pachymaran; and 10 mL of benzyl alcohol and Tween 80 is added in every 2 g of carboxymethyl pachymaran. The method comprises the steps of extracting poria cocos powder by refluxing and removing impurities to obtain pachymaran; then adding an organic solvent for modification and purification to obtain a carboxymethyl pachymaran pure product; and finally adding the water for injection, benzyl alcohol and Tween 80, thus obtaining the pachymaran injection. The injection is suitable for intramuscular injection, is good in drug absorption, has no irritant reaction, and is safe and reliable for use.

The invention relates to a granular temporary plugging agent preparation method, and belongs to the technical field of oilfield exploitation. Corn starch, pachymaran and the like are stirred and mixed, sodium hydroxide solution is added drop by drop at low temperature, reaction is performed, chloroacetic acid solution is added drop by drop, the solution is heated, mixed and filtered, filtrate is dialyzed and then concentrated to obtain concentrated solution, the concentrated solution and absolute ethyl alcohol are mixed and filtered at low temperature, filter residues are dried and then mixed with water and the like to obtain mixed solution A, acrylic acid, ammonia water and the like serving as raw materials are mixed to obtain mixed solution B, the mixed solution B is added into the mixed solution A, surfactants and the like are added to prepare viscous solution, and finally, the viscous solution is cooled, placed, dried and crushed. Temporary plugging agents prepared by the preparation method are good in heat resistance, have good plugging effects under the condition of high temperature and have a wide application prospect, and the strength of plugging layers is greatly improved.

The invention relates to a formula donkey milk formula with an anti-tumor efficacy. The formula donkey milk powder is characterized in that donkey milk powder is taken as the main material, and components, including lactobacillus acidophilus, lactobacillus rhamnosus, lactobacillus plantarum, lentinan, pachymaran, grifolan, fructo-oligosaccharide, galactooligosaccharide, isomaltose hypgather, synanthrin, polysaccharides in reed rhizome, apricot kernel meal, walnut powder, Chinese yam powder, lotus seed powder, lily root flour, wolfberry powder and the like are added. The formula donkey milk powder has the effects of inhibiting the growth of tumor cells and prolonging the living time of tumor-bearing mice.

The invention provides a preparation process of carboxymethyl pachymaran. The preparation process comprises three steps, namely poria cocos lye preparation, a decolouration and substitution reaction and alcohol precipitation; the preparation process is mainly characterized in that an alkalization reaction and an aqueous phase reaction are conducted simultaneously, the decolouration and substitution reaction is conducted continuously, and neutralization and alcohol precipitation are conducted integrally. The preparation process is short in consumed time, little in reagent consumption and low in emission. The prepared carboxymethyl pachymaran has the functions of enhancing immunity and assisting in tumor inhibition when being taken at a low taking dosage.

The invention discloses a multi-cereal crude fiber dietary fine dried noodle and a processing method thereof. Raw materials for the multi-cereal crude fiber dietary fine dried noodle comprise, by weight, 28 to 32 parts of strong noodle flour, 15 to 20 parts of brown rice, 7 to 9 parts of buckwheat, 7 to 9 parts of glutinous rice, 7 to 9 parts of corn, 7 to 9 parts of soya bean, 0.4 to 0.6 part ofginkgo leaves, 0.5 to 1.0 part of a pachymaran preparation, 4 to 6 parts of walnut, 4 to 6 parts of raw rehmannia root, 7 to 9 parts of seeds of Job's tears and 0.6 to 1.0 part of iodized edible salt. According to the invention, a formula for the multi-cereal crude fiber dietary fine dried noodle is reasonable, natural color and flavor of the produced multi-cereal crude fiber dietary fine dried noodle can be maintained on the basis that a pigment and a color protection agent are not used, the health property and organoleptic quality of the fine dried noodle are improved, and the fine dried noodle has the effects on reducing blood sugar, blood lipid and blood pressure and is applicable to mid-aged and elderly people and patients with cardiovascular and cerebrovascular diseases, obesity, constipation and diabetes.

The invention relates to a compound fungal polysaccharide preparation having functions of supporting healthy energy, strengthening spleen and stomach and boosting immunity. The preparation is mainly prepared from the following raw materials in percentage by weight: 10-50% of grifola frondosa, 10-50% of hericium erinaceus polysaccharide, 5-35% of ganoderma lucidum polysaccharide and 5-35% of pachymaran. Traditional Chinese medicine holds that supporting healthy energy is to build up healthful vital energy and consolidate essence, namely boosting the immunity, enhancing the disease resistance of a human body, preventing diseases and keeping away from sub-health. The grifola frondosa and the hericium erinaceus polysaccharide medicinal and edible fungal polysaccharides are capable of boosting immunity, protecting gastric mucosa, and improving such adverse reactions of tumor chemotherapy as lack of appetite, emesis, nausea and leucopenia. Traditional Chinese medicine thinks that lucid ganoderma (ganoderma lucidum polysaccharide) and poria cocos (pachymaran) can invigorate qi and strengthen spleen, and calm heart and nerves; modern researches prove that the preparation can boost immunity, resist tumors, assist in cancer therapy, and treat insomnia and dyspepsia. In conclusion, through rational combination of the four fungal polysaccharides, the preparation has clear functions of supporting healthy energy, strengthening spleen and stomach and boosting immunity, and has an obvious healthcare effect on sub-health; meanwhile, the preparation can be used for improving adverse reactions of tumor chemotherapy.

The invention relates to a preparation method of polysaccharide, which aims at providing a synthetic method replacing pachymaran. In order to realize the purpose, the preparation method adopts the detailed technical steps: firstly, the ethanol aqueous solution of NaOH or NaOH / urea aqueous solution is added in poria powder and is alkalified under the effect of ultrasonic wave for 30 minutes to 90 minutes; secondly, the reaction reagent is added in a reaction system to react for 50 minutes to 90 minuets under the effect of ultrasonic wave and the temperature of 50 DEG C to 70 DEG C, the mol ratio of the NaOH and the reaction reagent is 2 to 6 : 1, and the use amount of the ethanol aqueous solution or the urea aqueous solution is 20 mL / 1g to 30 mL / 1g of poria powder; and thirdly, the target product is obtained through leaching and acid washing the mixture obtained after reaction to neutrality and edulcoration. The preparation method has the advantages that the preparation method can perform one-step synthesis replacing pachymaran, the operation is convenient and time saving, and the cost is reduced; the ultrasonic wave is used to assist, the reaction speed is accelerated, and the substitution degree of the product is enhanced; the solution is secure, nontoxic and tractable.

The invention relates to a pharmaceutical composition suitable for mild disease of senile vascular dementia. The pharmaceutical composition is characterized by comprising 0.3-1.3g of tanshinone II A, 0.2-1.1g of ginsenoside Rg1, 0.075-0.3g of rheum emodin and 3.3-14g of pachymaran; preferably, the pharmaceutical composition also comprises components such as red flower, angelica sinensis, cinnamon, curcuma zedoary, euonymus alatus, caulis spatholobi, selaginella tamariscina, herba lycopi, rhodiola rosea, the fruit of Chinese wolfberry and the like for activating blood and tonifying qi.

The invention relates to carboxymethyl pachymaran with suitable substitution degree and a preparation method thereof, and belongs to the technical field of polymer polysaccharide preparation. The mthod comprises the steps that during the carboxymethylation modification process of pachymaran, an irradiation process is used, the proportion of reaction media is changed, and reaction temperature is regulated, thereby enhancing the efficiency of the carboxymethylation of pachymaran and the utilization rate of a raw material and an auxiliary material significantly, reducing the reaction time, and reducing the cost. The carboxymethyl pachymaran with substitution degree of about 0.7 can be obtained by the preparation method of the invention, and the product has the properties of higher antioxidant biological activity, white color and good solubility. Proved by the animal safety and toxicology evaluation test, the carboxymethyl pachymaran is classified into the safe and non-toxic level so as to be able to apply to the fields of foods, health products, feed additives and cosmetics and the like.

The invention discloses a tuckahoe biscuit and a preparation method thereof. The formula of the tuckahoe biscuit comprises the components of tuckahoe powder or pachymaran powder, glutinous rice flour, cane sugar, wheat flour, salt, bulking agent and edible vegetable oil, wherein the tuckahoe powder or pachymaran powder is superfine powder or nanometer powder. Natural raw materials are used in the formula of the tuckahoe biscuit, and the tuckahoe biscuit is free of other additives and is healthier as health food; the tuckahoe biscuit is excellent in mouthfeel and is crisp and delicious; effective constituents of the tuckahoe biscuit are easier to be absorbed by human body, and the health effect is more obvious.

The invention relates to a health care white spirit taking pine Tuckahoe as raw material and a making method thereof. The invention takes Tuckahoe as one of the raw materials and adopts cultivation, saccharification and biotransformation brewing processes to make a Tuckahoe health care white spirit featuring full play of the medicine efficacy, full nutrition and outstanding mouth feel. The invention is characterized in that the Tuckahoe health care white spirit is prepared by fermenting the raw materials alone without adding alcohol or other liquors. During brewing, lipide or high alcohol with higher concentration, oxy-compound, organic acid and Tuckahoe oligose as well as Pachymaran and the like with relatively low concentration form the rich and fresh, fine and mild flavor with long aftertaste of the Tuckahoe health care white spirit. The product also has the effects of cancer prevention and resistance, in particular the strong effects in adjusting organism metabolism, improving disintoxication immunity, promoting bio-synthesis of nucleic acid and protein, facilitating restoration and upgrade of damaged cells, thus having the functions of delaying the ageing process of cells and preventing diseases such as body decrease, kidney weakness, rheumatism and the like.

The invention discloses a preparation method of carboxymethyl pachymaran, belonging to the field of high-molecular polysaccharide. The method comprises the following steps: (1) dissolving dry powder of Poria cocos in a sodium hydroxide solution, conducting alkalization reaction to obtain an alkaline pachymaran solution, wherein the dry powder of Poria cocos is prepared by drying Poria cocos sclerotium, repeatedly crushing and sieving with No.5-7 sieves until the sieving rate is 90%; (2) detecting whether the weight of the pachymaran in the alkaline pachymaran solution is larger than 70% of the weight of the dry powder of Poria cocos, if yes, conducting the step (3); (3) adding a mixed solution of chloroacetic acid and sodium hydroxide to the alkaline pachymaran solution, conducting carboxymethylation to obtain a carboxymethyl pachymaran mixed liquor; and (4) separating and purifying the carboxymethyl pachymaran mixed liquor to obtain a finished product of carboxymethyl pachymaran. According to the invention, by strictly controlling the particle size of the dry powder of Poria cocos and the content of the pachymaran in the alkaline pachymaran solution in the preparation process of carboxymethyl pachymaran, the yield and product quality of carboxymethyl pachymaran are raised.

The invention belongs to the field of biomedicine, discloses a method for analyzing an anti-glandular cystitis action mechanism of pachymaran based on network pharmacology, and reports detailed targets and specific pharmacological mechanisms of pachymaran for preventing and treating glandular cystitis for the first time. The method comprises the following main points: obtaining a pachymaran pharmacological target and a glandular cystitis pathogen target through online database analysis of TCMSP, DisGeNET and the like; taking an intersection of the pachymaran and the glandular cystitis target to obtain a drug disease intersection target gene target, and constructing a related protein interaction network to screen a core target; further performing gene ontology GO biological process and KEGGpathway enrichment analysis on the core target by utilizing the R language related packet; and finally, constructing a drug target gene ontology functional pathway disease visualization diagram for deep analysis of a treatment mechanism. The method provided by the invention provides a new idea for explaining a research mechanism of pachymaran for exerting glandular cystitis resistance, and also provides an early-stage research basis for clinical application of pachymaran in glandular cystitis.

The invention relates to a method for comprehensively developing and applying poria cocos and a new application of the poria cocos. The method mainly comprises the following steps: smashing poria cocos sclerotium, adding water for soaking, performing reflux extraction and filtering, and concentrating and drying an extracting solution to obtain water-soluble pachymaran; performing extraction and suction filtration on a filter residue sodium hydroxide solution, washing filter residues with water to a neutral state to prepare dietary fiber, adjusting the pH value of filtrate to a weakly acidic state, filtering and drying to obtain a mixture of total triterpene of poria and alkali-soluble pachymaran, drying the mixture, adding the mixture into an ethanol aqueous solution, solving and filtering to obtain an alcoholic solution of the total triterpene of poria and an alkali-soluble pachymaran solid; washing the alkali-soluble pachymaran with water and drying; concentrating and drying the alcoholic solution of the total triterpene of poria to obtain total triterpene of poria. By adopting the method, the utilization rate of a poria cocos serving as a medicinal material is increased, and the comprehensive development and application values of the poria cocos on the aspects of medicine, foods, cosmetics and the like are increased.

The invention relates to the technical field of oligopeptide powder, in particular to multifunctional compound oligopeptide nutrition powder. The multifunctional compound oligopeptide nutrition powderis prepared from the following raw materials in parts by weight: 0.2 to 1 part of algal oligopeptide, 0.5 to 2 parts of soybean oligopeptide, 0.2 to 0.6 part of ginseng oligopeptide, 0.1 to 0.3 partof algal polysaccharides, 0.1 to 0.2 part of pachymaran, 0.3 to 0.5 part of ganoderan and 0.5 to 1 part of other auxiliary materials. The multifunctional compound oligopeptide nutrition powder disclosed by the invention has the functions of relieving the fatigue, resisting cancer, resisting oxidization, dispelling the effects of alcohol to protect the liver, adjusting the blood sugar, the blood pressure and the blood fact and improving the skin.

The invention provides a preparing method of a water-soluble pachymaran metal complex. The preparing method comprises the steps that firstly, pachymaran is dissolved in a NaOH solution, then the pH is regulated to be 3.5-5.5 with an acid solution, a composite plant hydrolase solution is added into the mixture, heat preservation is carried out for 4-6 h with a water bath at 50-70 DEG C, centrifuging, alcohol precipitation, washing and drying are carried out, and brown powder, namely, water-soluble pachymaran, is obtained; secondly, the water-soluble pachymaran is dissolved in deionized water, a metal ion solution is added, the pH is regulated to be 6-8, a reaction is carried out for 2-4 h with the temperature maintained at 50-80 DEG C, a metal complex is generated by the mixture, centrifuging, dialyzing and alcohol precipitation are carried out, light brown to brown precipitate, namely, a crude product, is obtained, washing and drying are carried out, and then the water-soluble pachymaran metal complex is obtained. The water-soluble pachymaran metal complex can be widely applied to development of foods, drugs, health-care products and the like to improve the medical and health-care performance of related products and reduce toxic and side effects, and has very wide application prospects.