The invention relates to a rare-earth-based flexible 
nuclear radiation protection material, and a preparation method and application thereof. The 
nuclear radiation protection material is a medium-heavy 
rare earth powder coated with a 
coupling agent and a 
defoamer, and the medium-heavy 
rare earth powder has a particle size less than 10 microns, the 
coupling agent is 0.5-2.0% the 
mass of the total medium-heavy 
rare earth powder, and the 
defoamer is 0.2-1.0% the weight of the total heavy rare earth powder. During the preparation, a medium-heavy rare earth powder is dried, and the dried medium-heavy rare-earth powder is coated with the 
coupling agent and the 
defoamer. According to the present invention, the rare earth 
composite material with good 
neutron absorption performance, no 
secondary radiation pollution, light weight and cheap price is selected for replacing an existing heavy 
metal composite material, and medium-heavy rare earth is used as a 
neutron absorption body for preparing theradiation protection product. The 
neutron shielding performance is higher than the shielding performance of traditional lead, 
boron carbide and other heavy elements; the protection effect on 
gamma ray is superior to those of lead, 
boron carbide and other heavy elements, and the protection material disclosed by the invention has good 
nuclear radiation shielding performance, mechanical properties and construction performance, and has advantages of 
crack resistance, 
corrosion resistance and 
heat resistance.